EC 1.6.4.2
- Product Name
- EC 1.6.4.2
- CAS No.
- 9001-48-3
- Chemical Name
- EC 1.6.4.2
- Synonyms
- GR;GLUTATHIONE REDUCTASE;GR TYPE VI;GR TYPE II;EC 1.8.1.7;EC 1.6.4.2;EC: 1.6.4.2;E.C. 1.8.1.7;GSH reductase;GSSG reductase
- CBNumber
- CB3770126
- Molecular Formula
- NULL
- Formula Weight
- 0
- MOL File
- Mol file
EC 1.6.4.2 Property
- storage temp.
- 2-8°C
- form
- suspension (aqueous)
- color
- yellow
- EPA Substance Registry System
- Reductase, glutathione (9001-48-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P284Wear respiratory protection.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- G3664
- Product name
- Glutathione Reductase from baker's yeast (S. cerevisiae)
- Purity
- ammonium sulfate suspension, 100-300?units/mg protein (biuret)
- Packaging
- 100units
- Price
- $56.1
- Updated
- 2024/03/01
- Product number
- G3664
- Product name
- Glutathione Reductase from baker's yeast (S. cerevisiae)
- Purity
- ammonium sulfate suspension, 100-300?units/mg protein (biuret)
- Packaging
- 500units
- Price
- $133
- Updated
- 2024/03/01
- Product number
- G9297
- Product name
- Glutathione Reductase human
- Purity
- buffered aqueous solution, ≥10?units/mg protein, recombinant, expressed in E. coli
- Packaging
- 500μg
- Price
- $353
- Updated
- 2024/03/01
- Product number
- G3664
- Product name
- Glutathione Reductase from baker's yeast (S. cerevisiae)
- Purity
- ammonium sulfate suspension, 100-300?units/mg protein (biuret)
- Packaging
- 2500Units
- Price
- $439
- Updated
- 2024/03/01
- Product number
- 356087
- Product name
- GR
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
EC 1.6.4.2 Chemical Properties,Usage,Production
Uses
Human glutathione reductase has been used in:
- glutathione reductase activity assay
- oxidative stress analysis
- redox assays
General Description
Glutathione reductase (GLR1) exists in mitochondrial and cytoplasmic isoforms. It shares sequence and structural homology to thioredoxin reductase, and is a flavin-containing oxidoreductase. Its active site is composed of a redox-active disulphide, and it requires NADPH for its catalytic activity. It is a widely present enzyme and is found in plants, bacteria, yeast, mice and humans.
Biochem/physiol Actions
Glutathione reductase IGR) is a crucial flavoenzyme in the antioxidant defense system. Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the process is converted to oxidized glutathione (GSSG). The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP+. The regenerated GSH is then available to detoxify more hydrogen peroxide. The enzyme uses FAD as a cofactor. GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm. Glutathione reductase shares a structural motif with a number of other proteins including aspartyl proteases, citrate synthase, EF hands, hemoglobins, lipocalins, and α/β hydrolases. GR is stimulated by melatonin and is reportedly irreversibly inhibited by a number of oxygen radical generating systems.
EC 1.6.4.2 Preparation Products And Raw materials
Raw materials
Preparation Products
EC 1.6.4.2 Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
- Tel
- --
- Fax
- --
- solutions@vwr.com
- Country
- United Kingdom
- ProdList
- 6548
- Advantage
- 82
View Lastest Price from EC 1.6.4.2 manufacturers
- Product
- EC 1.6.4.2 9001-48-3
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2024-08-30
- Product
- EC 1.6.4.2 9001-48-3
- Price
- US $1.00/KG
- Min. Order
- 100KG
- Purity
- 99.0%
- Supply Ability
- 1000kg
- Release date
- 2020-03-11