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2-Ethylaniline

Product Name
2-Ethylaniline
CAS No.
578-54-1
Chemical Name
2-Ethylaniline
Synonyms
NOE;OLEYLETHANOLAMIDE;Benzenamine, 2-ethyl-;AKOS 91138;O-ETHYLANILINE;o-ethyl-anilin;2-ETHYLANILINE;2-ethyl-anilin;Aniline, o-ethyl-;Aniline, 2-ethyl-
CBNumber
CB3853867
Molecular Formula
C8H11N
Formula Weight
121.18
MOL File
578-54-1.mol
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2-Ethylaniline Property

Melting point:
-44 °C (lit.)
Boiling point:
210 °C (lit.)
Density 
0.983 g/mL at 25 °C (lit.)
vapor density 
4.2 (vs air)
vapor pressure 
0.11 mm Hg ( 20 °C)
refractive index 
n20/D 1.559(lit.)
Flash point:
196 °F
storage temp. 
−20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
pka
pK1:4.42(+1) (25°C)
color 
Clear yellow to red-brownish
Water Solubility 
insoluble
BRN 
1841268
InChIKey
MLPVBIWIRCKMJV-UHFFFAOYSA-N
LogP
1.74
CAS DataBase Reference
578-54-1(CAS DataBase Reference)
NIST Chemistry Reference
2-Ethylaniline(578-54-1)
EPA Substance Registry System
o-Ethylaniline (578-54-1)
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Safety

Hazard Codes 
T
Risk Statements 
36/37/38-33-23/24/25
Safety Statements 
36/37/39-45-36/37-28A
RIDADR 
UN 2273 6.1/PG 3
WGK Germany 
3
RTECS 
BX9800000
8
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214980
Hazardous Substances Data
578-54-1(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E11803
Product name
2-Ethylaniline
Purity
98%
Packaging
100g
Price
$21.84
Updated
2024/03/01
Sigma-Aldrich
Product number
E11803
Product name
2-Ethylaniline
Purity
98%
Packaging
250g
Price
$44.82
Updated
2024/03/01
TCI Chemical
Product number
E0060
Product name
2-Ethylaniline
Purity
>98.0%(GC)(T)
Packaging
25mL
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
E0060
Product name
2-Ethylaniline
Purity
>98.0%(GC)(T)
Packaging
500mL
Price
$146
Updated
2024/03/01
Alfa Aesar
Product number
A14984
Product name
2-Ethylaniline, 97%
Packaging
100g
Price
$17.65
Updated
2024/03/01
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2-Ethylaniline Chemical Properties,Usage,Production

Description

2-Ethylaniline is a yellow liquid that turnsbrown on standing in air. Molecular weight = 121.20;Boiling point = 215℃; 210℃ at 760 mmHg; Freezing/Melting point = 44℃; Vapor pressure = 0.11 mmHg at20℃; Flash point = 85℃ (oc). Hazard Identification (basedon NFPA-704 M Rating System): Health 3, Flammability 2,Reactivity 0. Insoluble in water.

Chemical Properties

clear yellow to red-brownish liquid

Chemical Properties

2-Ethylaniline is a yellow liquid that turns brown on standing in air

Uses

Intermediate for pharmaceuticals, dyestuffs, pesticides, and other products.

Uses

2-?Ethylaniline is a reagent in the synthesis of bromoanthraquinones with different substituents producing novel dyes. Also used in the optimization of phoephoinositide 3-kinase inhibitor which is used in the synthesis.

Synthesis Reference(s)

The Journal of Organic Chemistry, 45, p. 4926, 1980 DOI: 10.1021/jo01312a021

General Description

A brown liquid. Insoluble in water and less dense than water. Hence floats on water. Flash point 185°F. May irritate skin, eyes and mucous membranes. Toxic by ingestion, inhalation or skin absorption.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Ethylaniline neutralizes acids in exothermic reactions to form salts plus water. May react with acids to release toxic fumes of aniline and oxides of nitrogen. Reacts violently with oxidizing materials. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Flammability and Explosibility

Not classified

Safety Profile

: A poison. Moderately toxic by ingestion. Flammable when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of aniline and NOx. See also NETHYLANILINE.

Potential Exposure

This material is used in making drugs, dyes, and pesticides.

First aid

Eye Contact: Immediately remove any contactlenses and flush with large amounts of water for at least15 min, occasionally lifting upper and lower lids. Seek medicalattention if any symptoms are present. Skin Contact: Quicklyremove contaminated clothing. Immediately wash area withlarge amounts of soap; promptly seek medical attention.Breathing: Remove the person from exposure. Begin rescuebreathing (using universal precautions, including resuscitationmask) if breathing has stopped and CPR if heart action hasstopped. Transfer promptly to a medical facility.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. 2-Ethylaniline must be stored to avoid contact withstrong acids (such as hydrochloric, sulfuric, and nitric),strong oxidizers, acid anhydrides (such as maleic anhydride), and chloroformates since violent reactions occur.Store in tightly closed containers in a cool, well-ventilatedarea. Sources of ignition, such as smoking and open flames,are prohibited where 2-ethylaniline is used, handled, orstored in a manner that could create a potential fire orexplosion hazard

Shipping

UN2273 2-Ethylaniline, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Combustible; vapor may form explosive mixture with air above 80℃. Decomposes on contact with light or air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, anhydrides, and chloroformates. Contact with metals may evolve flammable hydrogen gas.

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View Lastest Price from 2-Ethylaniline manufacturers

Hebei Jingbo New Material Technology Co., Ltd
Product
2-Ethylaniline 578-54-1
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20000
Release date
2024-01-03
Hebei Mojin Biotechnology Co., Ltd
Product
2-Ethylaniline 578-54-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-06
Hebei Guanlang Biotechnology Co,.LTD
Product
2-Ethylaniline 578-54-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2023-07-18

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