ChemicalBook > CAS DataBase List > Dexamethasone palmitate

Dexamethasone palmitate

Product Name
Dexamethasone palmitate
CAS No.
14899-36-6
Chemical Name
Dexamethasone palmitate
Synonyms
D01615;Lipotalon;Limethason;Limethasone;Limethason (tn);DXM-21-palmitate;DEXAMETHASOME PALMITATE;Dexamethasone palmitate;Dexamethasone-21-palmitate;Dexamethasone palmitate (jan)
CBNumber
CB41074390
Molecular Formula
C38H59FO6
Formula Weight
630.87
MOL File
14899-36-6.mol
More
Less

Dexamethasone palmitate Property

Melting point:
60-65 °C
Boiling point:
710.1±60.0 °C(Predicted)
Density 
1.12
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
11.99±0.70(Predicted)
color 
White to Pale Yellow
Stability:
Hygroscopic
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
D298830
Product name
Dexamethasone21-Palmitate
Packaging
250mg
Price
$480
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21400
Product name
Dexamethasone 21-palmitate
Packaging
250mg
Price
$700
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012845
Product name
DEXAMETHASONE PALMITATE
Purity
95.00%
Packaging
100MG
Price
$721.88
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21400
Product name
Dexamethasone 21-palmitate
Packaging
500mg
Price
$1200
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012845
Product name
DEXAMETHASONE PALMITATE
Purity
95.00%
Packaging
1G
Price
$1732.5
Updated
2021/12/16
More
Less

Dexamethasone palmitate Chemical Properties,Usage,Production

Description

Dexamethasone palmitate (DXP) is a prodrug of dexamethasone,which is a steroidal antinflammatory drug that is used to treat certain pain and inflammatory conditions such as asthma and rheumatoid arthritis. This prodrug was prepared to increase the distribution of the parent drug, dexamethasone, in the lungs for local drug delivery and to prevent its entry into the systemic circulation. This prodrug was developed as a powder formulation that needs to be administered via the pulmonary route so that it can easily reach into the lungs and show its effect locally.Normal delivery of dexamethasone enters systemic circulation very easily but this palmitate prodrug cannot easily enter into the systemic circula-tion. Within the lungs, the prodrug is acted upon by esterase enzyme that brings about hydrolysis,leading to the release of parent drug and increases the distribution of parentdrug inside the lungs (N'Guessan et al.,2018).

Chemical Properties

Colourless Thick Oil

Uses

A corticosteroid prodrug for the treatment of eye disorders.

Definition

ChEBI: Dexamethasone palmitate is an organic molecular entity.

Biochem/physiol Actions

Dexamethasone Palmitate is a lipophilic prodrug of a potent corticosteroid dexamethasone that is quickly taking up by macrophages via phagocytosis. Dexamethasone Palmitate inhibits function and migration of leukocytes and tissue macrophages.

Dexamethasone palmitate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Dexamethasone palmitate Suppliers

Jinan Jinchi Pharmaceutical Technology Co., LTD
Tel
15168890063 18888326116
Email
76337143@qq.com
Country
China
ProdList
54
Advantage
58
Hubei Guangao Biotechnology Co., Ltd
Tel
027-027-59223056 18162699093
Fax
027-59223056
Email
1208480011@qq.com
Country
China
ProdList
9924
Advantage
58
Wuhan Jingkangen Biomedical Technology Co., Ltd
Tel
13720134139 13720134139
Email
orders@jknbiochem.com
Country
China
ProdList
5797
Advantage
58
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai Hekang Biotechnology Co., Ltd.
Tel
18939837085
Fax
2880152141(QQ)
Email
youchemicals@gmail.com
Country
China
ProdList
1830
Advantage
55
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
More
Less

View Lastest Price from Dexamethasone palmitate manufacturers

Wuhan Haorong Biotechnology Co.,Ltd
Product
Dexamethasone palmitate 14899-36-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000
Release date
2023-07-27
Hebei Mojin Biotechnology Co., Ltd
Product
Dexamethasone palmitate 14899-36-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-10-11
Hubei Harvest Chemical CO.,Ltd
Product
Dexamethasone palmitate 14899-36-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000000000
Release date
2022-12-23

14899-36-6, Dexamethasone palmitateRelated Search:


  • (11β,16α)-9-Fluoro-11,17-dihydroxy-16-Methyl-21-[(1-oxohexadecyl)oxy]pregna-1,4-diene-3,20-dione
  • DEXAMETHASOME PALMITATE
  • Palmitic acid, 21-ester with 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione (8CI)
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11β,16α)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-palmitate (6CI, 8CI)
  • 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-palmitate
  • Dexamethasone palmitate
  • 21-(Palmitoyloxy)-9α-fluoro-11β,17α-dihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione
  • D01615
  • Dexamethasone palmitate (jan)
  • Limethason (tn)
  • Dexamethasone Impurity 20(Dexamethasone Palmitate)
  • Dexamethasone Impurity 21(Dexamethasone Palmitate)
  • Dexamethasone-21-palmitate
  • DXM-21-palmitate
  • Limethason
  • Limethasone
  • Lipotalon
  • Dexamethasone palmitate (DXP)
  • 21-Dehydrodexamethasone Dihydrate
  • Dexamethasone Palmitate Corticosteroid Raw Powder
  • lipophilic,prodrug,RAW 264.7,VEGF,Dexamethasone palmitate,Dexamethasone,Inhibitor,inflammation,inhibit,cytokine
  • Dexamethasone Impurity 20 CRS(Dexamethasone Palmitate CRS)
  • 2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl Palmitate
  • 14899-36-6
  • C38H59FO6
  • Drug Analogues
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids