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Dexamethasone palmitate

Product Name
Dexamethasone palmitate
CAS No.
14899-36-6
Chemical Name
Dexamethasone palmitate
Synonyms
D01615;Lipotalon;Limethason;Limethasone;Limethason (tn);DXM-21-palmitate;DEXAMETHASOME PALMITATE;Dexamethasone palmitate;Dexamethasone-21-palmitate;Dexamethasone palmitate (jan)
CBNumber
CB41074390
Molecular Formula
C38H59FO6
Formula Weight
630.87
MOL File
14899-36-6.mol
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Dexamethasone palmitate Property

Melting point:
60-65 °C
Boiling point:
710.1±60.0 °C(Predicted)
Density 
1.12
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
11.99±0.70(Predicted)
color 
White to Pale Yellow
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D298830
Product name
Dexamethasone21-Palmitate
Packaging
250mg
Price
$480
Updated
2021/12/16
ChemScene
Product number
CS-0102469
Product name
Dexamethasonepalmitate
Purity
>98.0%
Packaging
5mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-0102469
Product name
Dexamethasonepalmitate
Purity
>98.0%
Packaging
10mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21400
Product name
Dexamethasone 21-palmitate
Packaging
25mg
Price
$160
Updated
2021/12/16
ChemScene
Product number
CS-0102469
Product name
Dexamethasonepalmitate
Purity
>98.0%
Packaging
50mg
Price
$170
Updated
2021/12/16
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Dexamethasone palmitate Chemical Properties,Usage,Production

Description

Dexamethasone palmitate (DXP) is a prodrug of dexamethasone,which is a steroidal antinflammatory drug that is used to treat certain pain and inflammatory conditions such as asthma and rheumatoid arthritis. This prodrug was prepared to increase the distribution of the parent drug, dexamethasone, in the lungs for local drug delivery and to prevent its entry into the systemic circulation. This prodrug was developed as a powder formulation that needs to be administered via the pulmonary route so that it can easily reach into the lungs and show its effect locally.Normal delivery of dexamethasone enters systemic circulation very easily but this palmitate prodrug cannot easily enter into the systemic circula-tion. Within the lungs, the prodrug is acted upon by esterase enzyme that brings about hydrolysis,leading to the release of parent drug and increases the distribution of parentdrug inside the lungs (N'Guessan et al.,2018).

Chemical Properties

Colourless Thick Oil

Uses

A corticosteroid prodrug for the treatment of eye disorders.

Definition

ChEBI: Dexamethasone palmitate is an organic molecular entity.

Biochem/physiol Actions

Dexamethasone Palmitate is a lipophilic prodrug of a potent corticosteroid dexamethasone that is quickly taking up by macrophages via phagocytosis. Dexamethasone Palmitate inhibits function and migration of leukocytes and tissue macrophages.

Dexamethasone palmitate Preparation Products And Raw materials

Raw materials

Preparation Products

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Dexamethasone palmitate Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
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View Lastest Price from Dexamethasone palmitate manufacturers

Wuhan Haorong Biotechnology Co.,Ltd
Product
Dexamethasone palmitate 14899-36-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000
Release date
2023-07-27
Hebei Mojin Biotechnology Co., Ltd
Product
Dexamethasone palmitate 14899-36-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-10-11
Hubei Harvest Chemical CO.,Ltd
Product
Dexamethasone palmitate 14899-36-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000000000
Release date
2022-12-23

14899-36-6, Dexamethasone palmitateRelated Search:


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  • Drug Analogues
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