ChemicalBook > CAS DataBase List > 1,1,1-Trifluoroacetone

1,1,1-Trifluoroacetone

Product Name
1,1,1-Trifluoroacetone
CAS No.
421-50-1
Chemical Name
1,1,1-Trifluoroacetone
Synonyms
TRIFLUOROACETONE;1,1,1-TRIFLUORO-2-PROPANONE;Methyl trifluoromethyl ketone;2-Propanone, 1,1,1-trifluoro-;CH3COCF3;1,1,1-TrifL;uoroacetone;Trilfuoroacetone;1,1,1-Trifluoroaceto;1,1,1-Trifluroacetone
CBNumber
CB4123453
Molecular Formula
C3H3F3O
Formula Weight
112.05
MOL File
421-50-1.mol
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1,1,1-Trifluoroacetone Property

Melting point:
-78 °C
Boiling point:
22 °C(lit.)
Density 
1.252 g/mL at 25 °C(lit.)
vapor pressure 
13.62 psi ( 20 °C)
refractive index 
n20/D 1.3(lit.)
Flash point:
−23 °F
storage temp. 
2-8°C
solubility 
Chloroform, Methanol
form 
Liquid
color 
Clear colorless
Water Solubility 
Miscible
Sensitive 
Lachrymatory
BRN 
1748614
Stability:
Volatile
InChIKey
FHUDAMLDXFJHJE-UHFFFAOYSA-N
CAS DataBase Reference
421-50-1(CAS DataBase Reference)
NIST Chemistry Reference
2-Propanone, 1,1,1-trifluoro-(421-50-1)
EPA Substance Registry System
2-Propanone, 1,1,1-trifluoro- (421-50-1)
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Safety

Hazard Codes 
F+,Xi,F
Risk Statements 
12-36/37/38
Safety Statements 
16-26-29-33-36-7/9-9-37/39-39
RIDADR 
UN 1993 3/PG 1
WGK Germany 
3
F 
19
Hazard Note 
Flammable/Lachrymatory
TSCA 
T
HazardClass 
3
PackingGroup 
I
HS Code 
29147090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H224Extremely flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T62804
Product name
1,1,1-Trifluoroacetone
Purity
97%
Packaging
5g
Price
$45.6
Updated
2024/03/01
Sigma-Aldrich
Product number
T62804
Product name
1,1,1-Trifluoroacetone
Purity
97%
Packaging
25g
Price
$139
Updated
2024/03/01
TCI Chemical
Product number
T2921
Product name
1,1,1-Trifluoroacetone (in cylinder without valve) [To use this product charged in cylinder, a valve is required which is sold separately (Product Code:V0030)]
Packaging
100G
Price
$385
Updated
2021/12/16
Alfa Aesar
Product number
A13556
Product name
1,1,1-Trifluoroacetone, 95%
Packaging
25g
Price
$122
Updated
2024/03/01
Alfa Aesar
Product number
A13556
Product name
1,1,1-Trifluoroacetone, 95%
Packaging
100g
Price
$351
Updated
2024/03/01
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1,1,1-Trifluoroacetone Chemical Properties,Usage,Production

Chemical Properties

1,1,1-Trifluoroacetone is CLEAR COLOURLESS LIQUID

Uses

1,1,1-Trifluoroacetone is used as intermediate of bioactive substance and antihypertensive drug, and as effective synthetic building block and trifluoromethyl reaction reagent.

Uses

1,1,1-Trifluoroacetone is a general chemical reagent used in the synthesis of glucokinase-glucokinase regulatory protein) GK-GKRP disruptors which may act as potential targets for type II diabetics. Reactant for enantioselective cycloadditions.

Uses

Used in a synthesis of 2-trifluoromethyl-7-azaindoles starting with 2,6-dihalopyridines. The derived chiral imine was used to prepare enantiopure α-trifluoromethyl alanines and diamines via a Strecker reaction followed by either nitrile hydrolysis or reduction.

1,1,1-Trifluoroacetone Preparation Products And Raw materials

Raw materials

Preparation Products

4-Amino-2-(trifluoromethyl)quinoline 2-METHYL-4-TRIFLUOROMETHYL-NICOTINIC ACID 2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID 2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBALDEHYDE HEXAFLUOROACETYLACETONE
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1,1,1-Trifluoroacetone Suppliers

Belgium 1 Canada 1 China 160 Europe 1 France 1 Germany 4 India 4 Japan 3 Russia 1 Slovakia 1 Switzerland 1 The Netherlands 1 Ukraine 2 United Kingdom 6 United States 21 Global 208
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View Lastest Price from 1,1,1-Trifluoroacetone manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Trifluoroacetone 421-50-1
Price
US $3.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg
Release date
2024-08-21
Wuhan Boyuan Import & Export Co., LTD
Product
1, 1, 1-Trifluoroacetone
Price
US $20.00-10.00/kg
Min. Order
1kg
Purity
99.60%
Supply Ability
50tons
Release date
2023-12-11
Wuhan Boyuan Import & Export Co., LTD
Product
1, 1, 1-Trifluoroacetone 421-50-1
Price
US $20.00-15.00/kg
Min. Order
1kg
Purity
99.60%
Supply Ability
50tons
Release date
2023-12-08

421-50-1, 1,1,1-TrifluoroacetoneRelated Search:

Citric acid monohydrate Acetylacetone Calcium pyruvate Thenoyltrifluoroacetone Pyruvic acid Trifluoroacetic acid Triacetonamine 1,1,3-Trichloroacetone Trifluoroacetophenone Ethyl 4,4,4-trifluoroacetoacetate ZIRCONIUM TRIFLUOROACETYLACETONATE 4,4,4-Trifluoro-1-phenyl-1,3-butanedione 3-BROMO-1,1,1-TRIFLUOROACETONE,1-BROMO-3,3,3-TRIFLUOROACETONE 97%,1-BROMO-3,3,3-TRIFLUOROACETONE,3-Bromo-1,1,1-trifluoroacetone, min. 97% Propiophenone Phenylacetone METHYL TRIFLUOROPYRUVATE Ethyl trifluoropyruvate PALLADIUM(II) HEXAFLUOROACETYLACETONATE

  • TRIFLUOROACETONE
  • 1,1,1-trifluoro-2-propanon
  • 3,3,3-Trifluoroacetone
  • CH3COCF3
  • Methyl trifluoromethyl ketone
  • Trifluoromethyl methyl ketone
  • 1,1,1-TRIFLUOROACETONE
  • 1,1,1-TRIFLUORO-2-PROPANONE
  • Trilfuoroacetone
  • TFK,1,1,1-Trifluoroaceto
  • 1,1,1-Trifluoroacetone,95%
  • 1,1,1-Trifluoroacetone, 98+%
  • 1,1,1-Trifluroacetone
  • 2-Propanone, 1,1,1-trifluoro-
  • 1,1,1,-Trifluoroacetone 98%
  • 1,1,1-trifluoro-propan-2-one
  • 1,1,1-TRIFLUOROACETONE, 60% IN WATER
  • 1,1,1-Trifluoroacetone (TFK)
  • 1,1,three 1-fluorideacetone
  • 1,1,1-Trifluoroacetone (in cylinder without valve) [To use this product charged in cylinder, a valve is required which is sold separately (Product Code:V0030)]
  • 1,1,1-Trifluoroacetone ,99%
  • 1,1,1-Trifluoroaceto
  • 1,1,1-TRIFLUOROACETONE FOR SYNTHESIS
  • 1,1,1-TrifL
  • uoroacetone
  • Three fluorine acetone
  • 1,1,1-Trifluoroacetone,97%
  • 421-50-1
  • C3H3OF3
  • C3H3F3O
  • CF3COCH3
  • KETONE
  • Organic Building Blocks
  • Ketones
  • C3 to C6
  • Carbonyl Compounds
  • Building Blocks
  • C3 to C6
  • Carbonyl Compounds
  • Ketones