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Phosphodiesterase I

Product Name
Phosphodiesterase I
CAS No.
9025-82-5
Chemical Name
Phosphodiesterase I
Synonyms
EC 3.1.4.1;Power phos;IUB: 3.1.4.1;5'-EXONUCLEASE;PHOSPHODIESTERAS;EC 3.1.4.1 TYPE V;VENOM EXONUCLEASE;PHOSPHODIESTERASE;EC 3.1.4.1 TYPE VI;EC 3.1.4.1 TYPE IV
CBNumber
CB4133193
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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Phosphodiesterase I Property

storage temp. 
-20°C
form 
crude dried venom
color 
White to off-white
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
36/37/39-45
RIDADR 
2811
WGK Germany 
3
RTECS 
SZ5999500
HazardClass 
6.1(a)
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P284Wear respiratory protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P4506
Product name
Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake)
Purity
Type IV, crude dried venom
Packaging
100MG
Price
$91
Updated
2024/03/01
Sigma-Aldrich
Product number
P4506
Product name
Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake)
Purity
Type IV, crude dried venom
Packaging
500MG
Price
$191.4
Updated
2024/03/01
Sigma-Aldrich
Product number
P3243
Product name
Phosphodiesterase I from Crotalus adamanteus venom
Purity
vial of ≥100?units, Purified
Packaging
1vial
Price
$210
Updated
2024/03/01
Sigma-Aldrich
Product number
P3134
Product name
Phosphodiesterase I from Crotalus adamanteus venom
Purity
Type VI, crude dried venom, ≥0.01 unit/mg solid
Packaging
100mg
Price
$277
Updated
2024/03/01
Alfa Aesar
Product number
J20240
Product name
Phosphodiesterase I, from Crotalus adamanteus venom, Affymetrix/USB
Packaging
100units
Price
$185
Updated
2023/06/20
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Phosphodiesterase I Chemical Properties,Usage,Production

Description

The food enzyme phosphodiesterase I (oligonucleotide 5′‐nucleotidohydrolase; EC 3.1.4.1) is produced with the non‐genetically modified Leptographium procerum strain FDA by DSM Food Specialties B.V. The food enzyme is free from viable cells of the production organism. It is intended to be used to process yeast and yeast products. Phosphodiesterase I exhibits phosphohydrolase activity against NAD, nucleoside diphosphate sugars, and nucleoside tniphosphates. The enzyme was first isolated from rattlesnake venom and has been the subject of several reviews. Razzell partially purified a mammalian PDE I from a porcine kidney, and subsequent cell fractionation studies by other workers demonstrated the enzyme in the plasma membrane of rat liver cells[1-2].

References

[1] D J Morley. “Distribution of phosphodiesterase I in normal human tissues.” Journal of Histochemistry & Cytochemistry 35 1 (1987): 75–82.
[2] on Food Contact Materials, EFSA Panel Enzymes and Processing Aids (CEP). “Safety evaluation of the food enzyme phosphodiesterase I from the non-genetically modified Leptographium procerum strain FDA.” EFSA Journal 22 4 (2024).

Uses

Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. It is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is used in phosphodiesterase activation assays to hydrolyze AMP. Product P3134 is from crude, dried Crotalus adamanteus venom.

Biochem/physiol Actions

Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C.

Phosphodiesterase I Preparation Products And Raw materials

Raw materials

Preparation Products

Deoxynucleotide Disodium 5'-Inosinate 6-Thioguanine Adenosine 5'-monophosphate
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Phosphodiesterase I Suppliers

China 106 Germany 1 Switzerland 1 United States 7 Global 115
SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from Phosphodiesterase I manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
5'-phosphodiesterases 9025-82-5
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-08-25
Longyan Tianhua Biological Technology Co., Ltd
Product
phosphodiesterase i 9025-82-5
Price
US $50.00/KG
Min. Order
10KG
Purity
99.9%
Supply Ability
5000KG
Release date
2020-10-24
Career Henan Chemical Co
Product
phosphodiesterase i 9025-82-5
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

9025-82-5, Phosphodiesterase I Related Search:

Ethyl isocyanoacetate TERT-BUTYL ISOCYANIDE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Ferric acetylacetonate Benzyl isocyanide Tosylmethyl isocyanide PHENYLSELENOL Aluminum acetylacetonate SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) N-BUTYLISOCYANIDE 2,4-PENTANEDIONE, SILVER DERIVATIVE Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Cupric acetylacetonate COBALT(II) ACETYLACETONATE METHYL ISOCYANOACETATE PHOSPHODIESTERASE, TYPE II,PHOSPHODIESTERASE II TYPE I-SA,PHOSPHODIESTERASE, TYPE II, CALF SPLEEN,PHOSPHODIESTERASE II

  • EC 3.1.4.1 TYPE IV
  • EC 3.1.4.1 TYPE V
  • EC 3.1.4.1 TYPE VI
  • EC 3.1.4.1
  • IUB: 3.1.4.1
  • 5'-EXONUCLEASE
  • 5'-EXONUCLEASE TYPE IV
  • 5'-EXONUCLEASE TYPE V
  • 5'-EXONUCLEASE TYPE VI
  • PHOSPHODIESTERASE I
  • PHOSPHODIESTERASE I TYPE IV
  • PHOSPHODIESTERASE I TYPE V
  • PHOSPHODIESTERASE I TYPE VI
  • OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE
  • OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE IV
  • OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE V
  • OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE VI
  • VENOM EXONUCLEASE
  • 5'-phosphodiesterases
  • phosphodiesterase I from bovine*intestinal mucosa
  • phosphodiesterase I type vii*from crotalus atrox
  • PUTRESCINE DIHYDROCHLORIDE PLANT CELL*CU LTURE TESTE
  • PHOSPHODIESTERASE I TYPE V FROM*BOTHROPS ATROX
  • Phosphodiesteraseifromcrotalusadamanteus
  • phosphodiesterase i from crotalus adamanteus venom
  • PHOSPHODIESTERASE (FROM CROTALUS DURISSUS)
  • 5μ-Exonuclease, Oligonucleate 5μ-nucleotidohydrolase
  • Phosphodiesterase I from Bothrops atrox
  • Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake)
  • Phosphodiesterase I from Crotalus adamanteus venom,5′-Exonuclease, Oligonucleate 5′-nucleotidohydrolase
  • Power phos
  • Native Crotalus adamanteus venom Phosphodiesterase I
  • Native Crotalus atrox (Western Diamondback Rattlesnake) Phosphodiesterase I
  • Native Bothrops atrox Phosphodiesterase I
  • phosphodiesterases
  • PHOSPHODIESTERASE I USP/EP/BP
  • Phosphodiesterase I From Crotalus Adamanteus Venom BR,20U/mg
  • PHOSPHODIESTERAS
  • Phosphodiesterase Ⅰ
  • PHOSPHODIESTERASE
  • 9025-82-5
  • Cyclic Nucleotide Metabolism
  • Metabolomics
  • Nucleotide Metabolism
  • Biochemicals and Reagents
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Enzymes
  • General Metabolic Enzymes
  • G Proteins and Cyclic Nucleotides
  • General Metabolic Enzymes I-Z
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Class Index
  • 3.1.x.x Acting on esters
  • 3.x.x.x Hydrolases