Description References
ChemicalBook > CAS DataBase List > DL-Phenylalanine

DL-Phenylalanine

Description References
Product Name
DL-Phenylalanine
CAS No.
150-30-1
Chemical Name
DL-Phenylalanine
Synonyms
3-AMINO-3-PHENYLPROPANOIC ACID;DL-3-PHENYLALANINE;H-DL-PHE-OH;DL-PHENYALANINE;3 AMINO-PHENYLPROPIONIC ACID;D,L-PHE;DLPA 375;NSC 9959;FEMA 3726;DL-Phenylalani
CBNumber
CB4140195
Molecular Formula
C9H11NO2
Formula Weight
165.19
MOL File
150-30-1.mol
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DL-Phenylalanine Property

Melting point:
266-267 °C (dec.) (lit.)
Boiling point:
293.03°C (rough estimate)
Density 
1.1603 (rough estimate)
refractive index 
1.5200 (estimate)
FEMA 
3726 | D,L-PHENYLALANINE
storage temp. 
Store at RT.
solubility 
Water (Sparingly, Sonicated)
form 
Powder
pka
pK1 2.58; pK2 9.24(at 25℃)
color 
White
Odor
odorless
Odor Type
odorless
biological source
synthetic
Water Solubility 
14.11 g/L (25 ºC)
Merck 
14,7271
JECFA Number
1432
BRN 
1910407
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
0.24
CAS DataBase Reference
150-30-1(CAS DataBase Reference)
NIST Chemistry Reference
L-Phenylalanine(150-30-1)
EPA Substance Registry System
Phenylalanine (150-30-1)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34
Safety Statements 
37/39-24/25-45-36/37/39-27-26
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29224995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
147966
Product name
DL-Phenylalanine
Purity
ReagentPlus , 99%
Packaging
25g
Price
$37.4
Updated
2024/03/01
Sigma-Aldrich
Product number
147966
Product name
DL-Phenylalanine
Purity
ReagentPlus , 99%
Packaging
100g
Price
$73
Updated
2024/03/01
TCI Chemical
Product number
P0136
Product name
DL-Phenylalanine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
P0136
Product name
DL-Phenylalanine
Purity
>98.0%(HPLC)(T)
Packaging
250g
Price
$128
Updated
2021/12/16
Alfa Aesar
Product number
A10132
Product name
DL-Phenylalanine, 99%
Packaging
25g
Price
$25.1
Updated
2024/03/01
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DL-Phenylalanine Chemical Properties,Usage,Production

Description

As an essential amino acid, phenylalanine is necessary for the production of tyrosine in human body, which cannot be synthesized from more basic substances in humans and other animals, meaning that it is obtained only by ingestion of phenylalanine or phenylalanine- containing proteins, which is particularly rich in eggs, chicken, liver, beef, breast milk of mammals, and soybeans, etc. There are three forms of phenylalanine: L-phenylalanine, the natural form found in protein-rich foods, D-phenylalanine, the synthetic mirror image and DL-Phenylalanine (DLPA), the mixture of both forms made in the laboratory that can maximize benefits. DLPA is manufactured for medical, feed, and nutritional applications, which can be used to produce food and drink products. It is marketed as a nutritional supplement due to its reputed analgesic and antidepressant effects. Besides, it can be applied for depression, attention deficit-hyperactivity disorder (ADHD), Parkinson's disease, chronic pain, osteoarthritis, rheumatoid arthritis, alcohol withdrawal symptoms, and a skin disease called vitiligo.

References

https://en.wikipedia.org/wiki/Phenylalanine
http://www.livestrong.com/article/501701-what-are-the-benefits-of- dl-phenylalanine/
http://www.webmd.com/vitamins-supplements/ingredientmono-653- phenylalanine.aspx? activeingredientid=653&activeingredientname=phenylalanine

Chemical Properties

White crystalline powder

Chemical Properties

DL-Phenylalanine has a sweet taste. It is an essential amino acid that plays a key role in the biosynthesis of other amino acids and some neurotransmitters.

Occurrence

Phenylalanine is the most commonly found aromatic amino acid in proteins and enzymes with a molar ratio of 3.5% compared to the other amino acids, about double the amount of any other aromatic amino acid. Reported found in white bread, macaroni, egg noodles, corn flakes, corn grits, oatmeal, wheat bran, wheat flakes, shredded wheat, barley, brown rice, rye flour, whole grain wheat flour, buttermilk, blue cheese, cheddar cheese, cottage cheese, cream cheese, parmesan cheese, bacon, cured ham, frankfurters, pork sausage, canned red kidney beans, canned sweet corn, canned peas, canned lima beans, canned potatoes, canned asparagus, canned snap beans, canned beets, beef, lamb, fresh ham, veal round, beef liver, chicken, chicken liver, turkey and other natural sources.

Uses

DL-Phenylalanine is used to?relieve cases of minor depression?and other mood issues as well as and physical discomforts and pain. It is also used in acupuncture?anesthesia, alcohol withdrawal.

Uses

DL-Phenylalanine may be used in the synthesis of ternary piroxicam (Pir; 4-hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II).

Uses

Component of the artificial sweetner aspartame, q.v.; nutrient.

Preparation

By microbial bioengineered process.

Definition

ChEBI: An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.

General Description

Phenylalanine is an amino acid. It participates in the preparation of ternary piroxicam complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II). Characterization of these complexes by elemental analyses, molar conductance, IR, UV-Vis, magnetic moment, diffuse reflectance and X-ray powder diffraction methods has been conducted. Crystalline DL-phenylalanine was prepared by its reduction in silica gel by solubility method.

reaction suitability

reaction type: solution phase peptide synthesis

Side effects

When taken by mouth: L-phenylalanine is commonly consumed in foods. L-phenylalanine, D-phenylalanine, and DL-phenylalanine are possibly safe when used as medicine, short-term. Side effects might include anxiety, headache, and constipation. When applied to the skin: Phenylalanine cream is possibly safe when used in the short-term.

Purification Methods

dl-Phenylalanine crystallises from H2O or H2O/EtOH in large plates and is dried under vacuum over P2O5. S-Phenylalanine ethyl ester hydrochloride has m 156-158o and [ ] D -7.8o (c 2, H2O) after crystallisation from EtOH/Et2O [Billimoria & Cook J Chem Soc 2328 1949, Beilstein 14 IV 1556]. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2156-2175 1961, Beilstein 14 III 1229, 14 IV 1553.]

DL-Phenylalanine Preparation Products And Raw materials

Raw materials

L-Phenylalanine N-ACETYL-D-GALACTOSAMINE(GALACTOSE-13C6, 99%)

Preparation Products

DL-PHENYLALANINOL L-Phenylalanine Methyl 3-isoquinolinecarboxylate L-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE, 97 D-Phenylalanine
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View Lastest Price from DL-Phenylalanine manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
DL-Phenylalanine 150-30-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
50000KG/month
Release date
2024-10-22
Hebei Mujin Biotechnology Co.,Ltd
Product
DL-Phenylalanine 150-30-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99.6%
Supply Ability
50000KG/month
Release date
2024-10-22
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
DL-Phenylalanine 150-30-1
Price
US $99.00-66.00/kg
Min. Order
0.001kg
Purity
99%
Supply Ability
5000
Release date
2024-08-09

150-30-1, DL-PhenylalanineRelated Search:

Tris(hydroxymethyl)aminomethane 6-Aminocaproic acid L-Phenylalanine D-Phenylalanine ALTRENOGEST Phenprobamate N-(tert-Butoxycarbonyl)-L-phenylalanine Glycine L-Isoleucine L-Tryptophan L-Proline Melphalan Levodopa 4-BROMO-DL-PHENYLALANINE Liothyronine sodium O-PHOSPHO-L-TYROSINE CHLOROACETYL-L-TYROSINE Sodium levothyroxine

  • PHENYLALANINE, DL-
  • PHENYALANINE, DL-
  • RARECHEM AK HC T302
  • H-DL-PHE-OH
  • FEMA 3726
  • LABOTEST-BB LTBB000477
  • DL-ALPHA-AMINO-BETA-PHENYLPROPIONIC ACID
  • D,L-PHE
  • DL-PHENYALANINE
  • DL-PHENYLALANINE
  • DL-2-AMINO-3-PHENYLPROPANOIC ACID
  • DL-2-AMINO-3-PHENYLPROPIONIC ACID
  • DL-A-AMINOHYDROCINNAMIC ACID
  • DL-3-PHENYLALANINE
  • 3 AMINO-PHENYLPROPIONIC ACID
  • 3-AMINO-3-PHENYLPROPANOIC ACID
  • DLPA 375
  • DL-Phenylalanine,(±)-2-Amino-3-phenylpropionic acid
  • (+/-)-2-AMINO-3-PHENYLPROPIONIC ACID
  • 2-AMINO-3-PHENYLPROPIONIC ACID
  • Alanine, phenyl-, DL-
  • beta-Phenylalanine, dl-
  • DL-beta-Phenyl-alpha-alanine
  • DL-N-Phenylalanine
  • D,L, Phenylalanine, dry
  • DL-PHENYLALANINE 98.5+% FCC
  • DL-PHENYLALANINE CELL CULTURE TESTED
  • Dl-PhenylalanineForBiochemistry
  • AspartaMe IMpurity C
  • DL-Phenylalanine ReagentPlus(R), 99%
  • DL-Phenylalani
  • DL-Phenylalanine Vetec(TM) reagent grade, 98%
  • DL-Phenylalanine≥ 99% (Assay)
  • (±)-2-Amino-3-phenylpropionic acid DL-β-Phenylalanine
  • DL-Phenylalanine, FTIR
  • VLOOKUP(C2,[1]Export!$D:$H,5,0)
  • (2R)-2-ammonio-3-phenylpropanoate
  • DL-Phenylalanine, >98.0%(HPLC)
  • (+/-)-2-Amino-3-phenylpropionicacid=H-DL-Phe-OH
  • DL-α-Amino-β-phenylpropionic acid
  • (n)-2-amino-3-phenylpropionic acid
  • DL-PHENYLALANINE,FCC
  • PHENYLALANINE, DL-(P)
  • PHENYLALANINE, DL(RG)
  • DL-PHENYLALANINE(DL-ALPHA-AMINO-BETA-PHENYLPROPIONICACID)
  • DL-beta-Phenylalanine
  • (+-)-3-Phenyl-2-aminopropanoic acid
  • Alanine, phenyl-, DL- (8CI)
  • DL-a-Amino-b-phenylpropionic acid
  • DL-b-Phenyl-a-alanine
  • DL-b-Phenylalanine
  • NSC 9959
  • Phenylalanine (9CI)
  • DL-Phenylalanin
  • (R,S)-2-Amino-3-phenyl-propionic acid
  • rac-(2R*)-3-Phenyl-2-aminopropionic acid
  • rac-(R*)-2-Amino-3-phenylpropionic acid
  • DL-Phenylalanine,99%