4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

Product Name: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
CAS No.: 162012-67-1
Chemical Name: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
Synonyms: N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline;N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine;N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine;)-7-fL;Afatinib Impurity 76;Afatinib/Dacomitinib;uoro-6-nitroquninazoL;Afatinib intermediate A;4-(3-chloro-4-fiuoro-phen...
CBNumber: CB41512555
Molecular Formula: C14H7ClF2N4O2
Formula Weight: 336.68
MOL File: 162012-67-1.mol

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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Property

Melting point:: 242-244℃
Boiling point:: 489℃
Density: 1.616
Flash point:: 249℃
storage temp.: 2-8°C(protect from light)
solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
form: Solid
pka: 5.07±0.70(Predicted)
color: Yellow to Dark Yellow

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Safety

HS Code: 2933.59.8000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3276
Product name: N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine
Packaging: 5G
Price: $163
Updated: 2024/03/01

TCI Chemical

Product number: C3276
Product name: N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine
Packaging: 25G
Price: $486
Updated: 2024/03/01

TRC

Product number: C376250
Product name: 4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinazoline
Packaging: 100mg
Price: $95
Updated: 2021/12/16

TRC

Product number: C376250
Product name: 4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinazoline
Packaging: 10g
Price: $970
Updated: 2021/12/16

ChemScene

Product number: CS-M0991
Product name: N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
Purity: >99.0%
Packaging: 10g
Price: $32
Updated: 2021/12/16

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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Chemical Properties,Usage,Production

Uses

4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Suppliers

Americas 1 China 324 Europe 1 India 11 Japan 1 United Kingdom 2 United States 8 Global 348

Jinan XuanDe Chemical Co., Ltd.

Tel: 0531-88803958; 18866891188
Fax: 0531-82777287
Email: zhaojiangxia@shiningpharm.com
Country: China
ProdList: 275
Advantage: 58

Anhui Dexinjia Biopharm Co., Ltd

Tel: 0531-82375878 15269101859
Email: 2710825968@qq.com
Country: China
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TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.

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Email: marketing@pharmacn.com
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Energy Chemical

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Email: sales@sinch.com.cn
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Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
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Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
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Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
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ProdList: 42958
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View Lastest Price from 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- manufacturers

Nanjing Fred Technology Co., Ltd

Product: N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine 162012-67-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-20

Hebei Yanxi Chemical Co., Ltd.

Product: N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 162012-67-1
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-09-06

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Afatinib impurity 76
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98%
Supply Ability: 500mg
Release date: 2024-06-04

162012-67-1, 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-Related Search:

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Aprepitant methyl(E)-4-(methylamino)but-2-enoate (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine TRANS-4-AMINOCROTONIC ACID 7-Fluoro-4-quinazolone Afatinib impurity 45 Benzyl dihydrogen phosphate (2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine trans-4-Dimethylaminocrotonic acid hydrochloride (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine Afatinib Afatinib dimaleate (S)-(+)-3-Hydroxytetrahydrofuran Afatinib (BIBW 2992) 7-Fluoro-6-nitro-4-hydroxyquinazoline 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

4-(3-chloro-4-fiuoro-phen...

4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline

N-(3-chloro-4-fluorophenyl)-N-(7-fluoro-6-nitroquinazolin-4-yl)acetaMide

(3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine

N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine

Afatinib intermediate A

3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)

N-(3-chloro-4-fluorophenyl)-7-fiuoro-6-nitro-4-quinazolinaMine

N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine (3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine

Afatinib int-1 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine

N-(3-Cl-4-F-phenyl)-7-F-6-NO2-4-quinazolinamine

4-Quizolimine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

4-[(3-Chloro-4-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline

Afatinib Impurity 76

N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro quinazoline-4-amine

N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquninazoline

uoro-6-nitroquninazoL

N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine

)-7-fL

4- quinazoline amine, N- (3-chloro-4-fluorophenyl) -7-fluoro-6-nitro -

4-(3-Chloro-4-fluoroanilino)-7-fluoro-6-nitroquinazoline

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- ISO 9001：2015 REACH

N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-ni...

Afatinib/Dacomitinib

N - (3-chloro-4-fluorophenyl) -7-fluoro-6-nitro-4-quinazoline amine

162012-67-1

C14H7ClF2N4O2

API intermediates

162012-67-1