ChemicalBook > CAS DataBase List > 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

Product Name
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
CAS No.
162012-67-1
Chemical Name
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
Synonyms
N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline;N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine;N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine;)-7-fL;Afatinib Impurity 76;Afatinib/Dacomitinib;uoro-6-nitroquninazoL;Afatinib intermediate A;4-(3-chloro-4-fiuoro-phen...
CBNumber
CB41512555
Molecular Formula
C14H7ClF2N4O2
Formula Weight
336.68
MOL File
162012-67-1.mol
More
Less

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Property

Melting point:
242-244℃
Boiling point:
489℃
Density 
1.616
Flash point:
249℃
storage temp. 
2-8°C(protect from light)
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
5.07±0.70(Predicted)
color 
Yellow to Dark Yellow
More
Less

Safety

HS Code 
2933.59.8000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
C3276
Product name
N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine
Packaging
5G
Price
$163
Updated
2024/03/01
TCI Chemical
Product number
C3276
Product name
N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine
Packaging
25G
Price
$486
Updated
2024/03/01
TRC
Product number
C376250
Product name
4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinazoline
Packaging
10g
Price
$970
Updated
2021/12/16
TRC
Product number
C376250
Product name
4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinazoline
Packaging
100mg
Price
$95
Updated
2021/12/16
AK Scientific
Product number
B693
Product name
4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline
Packaging
5g
Price
$98
Updated
2021/12/16
More
Less

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Chemical Properties,Usage,Production

Uses

4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Suppliers

Jinan XuanDe Chemical Co., Ltd.
Tel
0531-88803958; 18866891188
Fax
0531-82777287
Email
zhaojiangxia@shiningpharm.com
Country
China
ProdList
275
Advantage
58
Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375878 15269101859
Email
2710825968@qq.com
Country
China
ProdList
297
Advantage
58
Shanghai Famo Bio-chemical Technology Company Ltd.
Tel
021-36680027 15821745250
Email
fengqiang@famobiotech.com
Country
China
ProdList
539
Advantage
56
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60182192,1339732154 18722583064
Fax
86-22-60979672
Email
marketing@pharmacn.com
Country
China
ProdList
112
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9414
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
More
Less

View Lastest Price from 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- manufacturers

Nanjing Fred Technology Co., Ltd
Product
N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine 162012-67-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-20
Hebei Yanxi Chemical Co., Ltd.
Product
N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 162012-67-1
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-06
Hebei Mojin Biotechnology Co.,Ltd
Product
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- 162012-67-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-09-05

162012-67-1, 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-Related Search:


  • 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
  • N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
  • 4-(3-chloro-4-fiuoro-phen...
  • 4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline
  • N-(3-chloro-4-fluorophenyl)-N-(7-fluoro-6-nitroquinazolin-4-yl)acetaMide
  • (3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine
  • N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine
  • Afatinib intermediate A
  • 3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)
  • N-(3-chloro-4-fluorophenyl)-7-fiuoro-6-nitro-4-quinazolinaMine
  • N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine (3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine
  • Afatinib int-1 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine
  • N-(3-Cl-4-F-phenyl)-7-F-6-NO2-4-quinazolinamine
  • 4-Quizolimine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
  • 4-[(3-Chloro-4-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline
  • Afatinib Impurity 76
  • N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro quinazoline-4-amine
  • N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquninazoline
  • uoro-6-nitroquninazoL
  • N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine
  • )-7-fL
  • 4- quinazoline amine, N- (3-chloro-4-fluorophenyl) -7-fluoro-6-nitro -
  • 4-(3-Chloro-4-fluoroanilino)-7-fluoro-6-nitroquinazoline
  • 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- ISO 9001:2015 REACH
  • N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
  • 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-ni...
  • Afatinib/Dacomitinib
  • N - (3-chloro-4-fluorophenyl) -7-fluoro-6-nitro-4-quinazoline amine
  • 162012-67-1
  • C14H7ClF2N4O2
  • API intermediates
  • 162012-67-1