Pertuzumab

Product Name: Pertuzumab
CAS No.: 380610-27-5
Chemical Name: Pertuzumab
Synonyms: 2C4;Omnitarg;pertuzumab;Unii-K16aiq8ctm;Pertuzumab-Perjeta;Pertuzumab (anti-HER2);Research Grade Pertuzumab(DHC09602);Immunoglobulin G1, anti-(human V (receptor)) (human-mouse monoclonal 2C4 heavy chain), disulfide with human-mouse monoclonal 2C4 kappa-chain, dimer
CBNumber: CB41856062
Molecular Formula: C17H27NO2
Formula Weight: 277.40178
MOL File: 380610-27-5.mol

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Safety

Hazardous Substances Data: 380610-27-5(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7826
Product name: Pertuzumab
Packaging: 1mg
Price: $348
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BP165593
Product name: Pertuzumab
Packaging: 1mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-7826
Product name: Pertuzumab
Packaging: 5mg
Price: $705
Updated: 2021/12/16

ChemScene

Product number: CS-7826
Product name: Pertuzumab
Packaging: 25mg
Price: $2650
Updated: 2021/12/16

ChemScene

Product number: CS-7826
Product name: Pertuzumab
Packaging: 50mg
Price: $4250
Updated: 2021/12/16

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Pertuzumab Chemical Properties,Usage,Production

Description

Pertuzumab is an anti-human epidermal growth factor receptor 2 (HER2) antibody that was approved by the US FDA in June 2012 for use in combination with trastuzumab (Herceptin?) and docetaxel chemotherapy for the treatment of people with HER2-positive (HER2⁺) metastatic breast cancer (mBC) who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease. Pertuzumab inhibits HER2 dimer formation with other HER members, such as HER1 and HER3, thus inhibiting the downstream signaling processes associated with tumor growth and progression. Pertuzumab is the first HER2 dimerization inhibitor to reach the market. The mechanism of actions of trastuzumab and pertuzumab are believed to complement each other and provide a more comprehensive inhibition of tumor growth than either agent alone. Preclinical data showed that the combination of trastuzumab and pertuzumab has a strongly enhanced antitumor effect and induces tumor regression in xenograft models, something that cannot be achieved by either monotherapy alone.

Originator

Genentech, a member of the Roche Group (United States)

Uses

Anti-neoplastic.

brand name

Perjeta

Clinical Use

Monoclonal antibody:
Treatment of HER2 receptor +ve breast cancer

Metabolism

Antibodies are cleared mainly by catabolism.

Pertuzumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Pertuzumab Suppliers

China 68 China Hong Kong 1 India 1 United Kingdom 1 United States 6 Global 77

Wuhan Sunrise Technology Development Co., Ltd.

Tel: 027-027-83314682 13554138826
Fax: +86 (27) 8331-4682
Email: whsrtech@vip.163.com
Country: China
ProdList: 300
Advantage: 62

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2893
Advantage: 58

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3421
Advantage: 58

LUCKY PHARMA CO., LIMITED

Tel: 0571-86403260 86403970
Fax: 0571-86403970
Email: lucky@lkbiology.com
Country: China
ProdList: 243
Advantage: 58

Taizhou KEDE Chemical Co., Ltd

Tel: 0576-84613060 13093829633
Fax: 0576-84613060
Email: sales@kedechemical.com
Country: China
ProdList: 298
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4121
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

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View Lastest Price from Pertuzumab manufacturers

Hangzhou Huarong Pharm Co., Ltd.

Product: Pertuzumab 380610-27-5
Price: US $0.00-0.00/mg
Min. Order: 5mg
Purity: 99%
Supply Ability: 50KG
Release date: 2021-09-15

Career Henan Chemical Co

Product: Pertuzumab 380610-27-5
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-01-02

380610-27-5, PertuzumabRelated Search:

Toltrazuril Rituximab Ethyl isocyanoacetate METHYL ISOCYANOACETATE Aluminum acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Cupric acetylacetonate SALCOMINE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) 2,4-PENTANEDIONE, SILVER DERIVATIVE COBALT(II) ACETYLACETONATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) PHENYLSELENOL Benzyl isocyanide Ferric acetylacetonate Tosylmethyl isocyanide TERT-BUTYL ISOCYANIDE

pertuzumab

2C4

Immunoglobulin G1, anti-(human V (receptor)) (human-mouse monoclonal 2C4 heavy chain), disulfide with human-mouse monoclonal 2C4 kappa-chain, dimer

Omnitarg

Unii-K16aiq8ctm

Pertuzumab (anti-HER2)

Pertuzumab-Perjeta

Research Grade Pertuzumab(DHC09602)

380610-27-5