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Pertuzumab

Product Name
Pertuzumab
CAS No.
380610-27-5
Chemical Name
Pertuzumab
Synonyms
2C4;Omnitarg;pertuzumab;Unii-K16aiq8ctm;Pertuzumab-Perjeta;Pertuzumab (anti-HER2);Research Grade Pertuzumab(DHC09602);Immunoglobulin G1, anti-(human V (receptor)) (human-mouse monoclonal 2C4 heavy chain), disulfide with human-mouse monoclonal 2C4 kappa-chain, dimer
CBNumber
CB41856062
Molecular Formula
C17H27NO2
Formula Weight
277.40178
MOL File
380610-27-5.mol
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Pertuzumab Property

form 
Liquid
color 
Colorless to light yellow
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Safety

Hazardous Substances Data
380610-27-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-7826
Product name
Pertuzumab
Packaging
1mg
Price
$348
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP165593
Product name
Pertuzumab
Packaging
1mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-7826
Product name
Pertuzumab
Packaging
5mg
Price
$705
Updated
2021/12/16
ChemScene
Product number
CS-7826
Product name
Pertuzumab
Packaging
25mg
Price
$2650
Updated
2021/12/16
ChemScene
Product number
CS-7826
Product name
Pertuzumab
Packaging
50mg
Price
$4250
Updated
2021/12/16
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Pertuzumab Chemical Properties,Usage,Production

Description

Pertuzumab is an anti-human epidermal growth factor receptor 2 (HER2) antibody that was approved by the US FDA in June 2012 for use in combination with trastuzumab (Herceptin?) and docetaxel chemotherapy for the treatment of people with HER2-positive (HER2+) metastatic breast cancer (mBC) who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease. Pertuzumab inhibits HER2 dimer formation with other HER members, such as HER1 and HER3, thus inhibiting the downstream signaling processes associated with tumor growth and progression. Pertuzumab is the first HER2 dimerization inhibitor to reach the market. The mechanism of actions of trastuzumab and pertuzumab are believed to complement each other and provide a more comprehensive inhibition of tumor growth than either agent alone. Preclinical data showed that the combination of trastuzumab and pertuzumab has a strongly enhanced antitumor effect and induces tumor regression in xenograft models, something that cannot be achieved by either monotherapy alone.

Originator

Genentech, a member of the Roche Group (United States)

Uses

Anti-neoplastic.

brand name

Perjeta

Clinical Use

Monoclonal antibody:
Treatment of HER2 receptor +ve breast cancer

Metabolism

Antibodies are cleared mainly by catabolism.

Pertuzumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Pertuzumab Suppliers

Wuhan Sunrise Technology Development Co., Ltd.
Tel
27-027-83314682 13554138826
Fax
+86 (27) 8331-4682
Email
whsrtech@vip.163.com
Country
China
ProdList
230
Advantage
62
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2866
Advantage
58
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4727
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
LUCKY PHARMA CO., LIMITED
Tel
0571-86403260 86403970
Fax
0571-86403970
Email
lucky@lkbiology.com
Country
China
ProdList
243
Advantage
58
Taizhou KEDE Chemical Co., Ltd
Tel
0576-84613060 13093829633
Fax
0576-84613060
Email
sales@kedechemical.com
Country
China
ProdList
298
Advantage
60
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4575
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
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View Lastest Price from Pertuzumab manufacturers

Hangzhou Huarong Pharm Co., Ltd.
Product
Pertuzumab 380610-27-5
Price
US $0.00-0.00/mg
Min. Order
5mg
Purity
99%
Supply Ability
50KG
Release date
2021-09-15
Career Henan Chemical Co
Product
Pertuzumab 380610-27-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-01-02

380610-27-5, PertuzumabRelated Search:


  • pertuzumab
  • 2C4
  • Immunoglobulin G1, anti-(human V (receptor)) (human-mouse monoclonal 2C4 heavy chain), disulfide with human-mouse monoclonal 2C4 kappa-chain, dimer
  • Omnitarg
  • Unii-K16aiq8ctm
  • Pertuzumab (anti-HER2)
  • Pertuzumab-Perjeta
  • Research Grade Pertuzumab(DHC09602)
  • 380610-27-5