Sodium 3-nitrobenzenesulphonate
- Product Name
- Sodium 3-nitrobenzenesulphonate
- CAS No.
- 127-68-4
- Chemical Name
- Sodium 3-nitrobenzenesulphonate
- Synonyms
- RESIST SALT;SODIUM 3-NITROBENZENESULFONATE;3-NITROBENZENESULFONIC ACID SODIUM SALT;ludigol;3-Nitrobenzenesulfonate;3-nitrobenzenesulphonate;tiskan;SODIUM M-NITROBENZENESULFONATE;SMNBS;Ludigo
- CBNumber
- CB4193939
- Molecular Formula
- C6H4NNaO5S
- Formula Weight
- 225.15
- MOL File
- 127-68-4.mol
Sodium 3-nitrobenzenesulphonate Property
- Melting point:
- 350 °C
- Boiling point:
- 217.5°C
- Density
- 0.45 g/cm3 (20 °C)
- bulk density
- 450kg/m3
- vapor pressure
- 10.3Pa at 25℃
- Flash point:
- 100 °C
- storage temp.
- Store below +30°C.
- solubility
- water: soluble50mg/mL, clear to slightly hazy, faintly yellow to yellow
- form
- Crystalline Powder
- pka
- 0[at 20 ℃]
- color
- Light yellow
- PH
- 8 (50g/l, H2O, 23℃)
- Water Solubility
- 200 g/L (20 ºC)
- Sensitive
- Hygroscopic
- BRN
- 3639982
- Stability:
- Stable. Hygroscopic. Incompatible with strong oxidizing agents.
- InChIKey
- LJRGBERXYNQPJI-UHFFFAOYSA-M
- LogP
- -2.61 at 25℃
- CAS DataBase Reference
- 127-68-4(CAS DataBase Reference)
- EPA Substance Registry System
- Sodium 3-Nitrobenzenesulfonate (127-68-4)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36-43
- Safety Statements
- 24-26-37
- WGK Germany
- 1
- RTECS
- DB7195000
- Autoignition Temperature
- 355 °C
- TSCA
- Yes
- HS Code
- 29049085
- Hazardous Substances Data
- 127-68-4(Hazardous Substances Data)
- Toxicity
- LD50 orally in Rabbit: > 2000 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.06548
- Product name
- 3-Nitrobenzenesulfonic acid sodium salt
- Purity
- for synthesis
- Packaging
- 100g
- Price
- $29.3
- Updated
- 2025/07/31
- Product number
- 8.06548
- Product name
- 3-Nitrobenzenesulfonic acid sodium salt
- Purity
- for synthesis
- Packaging
- 1kg
- Price
- $80.9
- Updated
- 2025/07/31
- Product number
- 225193
- Product name
- Sodium 3-nitrobenzenesulfonate
- Purity
- 98%
- Packaging
- 100g
- Price
- $48.2
- Updated
- 2025/07/31
- Product number
- 225193
- Product name
- Sodium 3-nitrobenzenesulfonate
- Purity
- 98%
- Packaging
- 500g
- Price
- $74.4
- Updated
- 2025/07/31
- Product number
- N0141
- Product name
- Sodium 3-Nitrobenzenesulfonate
- Purity
- >95.0%(T)
- Packaging
- 25g
- Price
- $19
- Updated
- 2025/07/31
Sodium 3-nitrobenzenesulphonate Chemical Properties,Usage,Production
Chemical Properties
solid
Uses
Sodium 3-nitrobenzenesulfonate is a reagent in the synthesis of azetidinyl ketolides for treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.
Flammability and Explosibility
Non flammable
Synthesis
98-95-3
127-68-4
1) In a 500 mL four-neck flask equipped with a thermometer, mechanical stirrer and exhaust gas absorption device, 246 g (2.0 mol) of nitrobenzene and 139 g (1.2 mol) of chlorosulfonic acid were added. Stirring was initiated and heated to 120 °C, and the sulfonation reaction was maintained at this temperature for 3 hours. The hydrogen chloride gas generated during the reaction was introduced into 200 mL of deionized water through the tail gas absorption device, and finally an aqueous hydrogen chloride solution with a mass concentration of 17.5% was obtained. (2) After the reaction was completed, the reaction mixture was cooled to room temperature, 500 mL of water and 63.6 g (0.6 mol) of sodium carbonate were added and stirred thoroughly. The oil layer was separated after standing. The oil layer was washed three times with 500 mL of water and subsequently dried over 35 g of molecular sieves to give 95 g of recovered nitrobenzene with 99.3% purity. The aqueous layer solution was dried by a spray drying unit (feed rate 15-20 mL/min, inlet temperature 300 °C, outlet temperature 100 °C) to give 266 g of dried sodium nitrobenzenesulfonate product with 99.0% purity and 98.4% yield (in terms of consumed nitrobenzene).
References
[1] Patent: CN108997175, 2018, A. Location in patent: Paragraph 0046-0059; 0062-0066
Sodium 3-nitrobenzenesulphonate Preparation Products And Raw materials
Raw materials
Preparation Products
Sodium 3-nitrobenzenesulphonate Suppliers
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View Lastest Price from Sodium 3-nitrobenzenesulphonate manufacturers
- Product
- Sodium 3-nitrobenzenesulphonate 127-68-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- ≥99%
- Supply Ability
- 1000mt/year
- Release date
- 2022-09-29
- Product
- 3-Nitrobenzenesulfonic Acid Sodium Salt 127-68-4
- Price
- US $70.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-06-06
- Product
- Sodium 3-Nitrobenzenesulphonate 127-68-4
- Price
- US $180.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-06