ChemicalBook > CAS DataBase List > 3-BROMO-2,6-DIFLUOROBENZALDEHYDE

3-BROMO-2,6-DIFLUOROBENZALDEHYDE

Product Name: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE
CAS No.: 398456-82-1
Chemical Name: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE
Synonyms: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE;3-Bromo-2,6-difluorobenzaldehyde98%;Benzaldehyde, 3-bromo-2,6-difluoro-;3-Bromo-2,6-difluorobenzaldehyde 98%;3-BROMO-2,6-DIFLUOROBENZALDEHYDE ISO 9001：2015 REACH
CBNumber: CB4196011
Molecular Formula: C7H3BrF2O
Formula Weight: 221
MOL File: 398456-82-1.mol

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3-BROMO-2,6-DIFLUOROBENZALDEHYDE Property

Melting point:: 53-57°C
Boiling point:: 223℃
Density: 1.758
Flash point:: 89℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder
color: White
Sensitive: Air Sensitive
InChI: InChI=1S/C7H3BrF2O/c8-5-1-2-6(9)4(3-11)7(5)10/h1-3H
InChIKey: OXBHKEYDKAWFLS-UHFFFAOYSA-N
SMILES: C(=O)C1=C(F)C=CC(Br)=C1F

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2913000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS022691
Product name: 3-Bromo-2,6-difluorobenzaldehyde
Packaging: 100 mg
Price: $36.7
Updated: 2025/07/31

TRC

Product number: B700380
Product name: 3-Bromo-2,6-difluorobenzaldehyde
Packaging: 10mg
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2615-B-01
Product name: 3-Bromo-2,6-difluorobenzaldehyde
Purity: 98%
Packaging: 5G
Price: $47
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB80689
Product name: 3-Bromo-2,6-difluorobenzaldehyde
Packaging: 2g
Price: $50
Updated: 2021/12/16

Matrix Scientific

Product number: 095471
Product name: 3-Bromo-2,6-difluorobenzaldehyde
Purity: 98%
Packaging: 1g
Price: $57
Updated: 2021/12/16

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3-BROMO-2,6-DIFLUOROBENZALDEHYDE Chemical Properties,Usage,Production

Uses

3-Bromo-2,6-difluorobenzaldehyde is used as a pharmaceutical intermediate.

Synthesis

348-57-2

68-12-2

398456-82-1

Lithium diisopropylammonium (2M THF solution, 13 mL, 26 mmol) was slowly added dropwise to a solution of anhydrous THF (80 mL) of 1-bromo-2,4-difluorobenzene (5.0 g, 25.9 mmol) at -78 °C, and the reaction was stirred for 1 h at -78 °C maintaining the temperature. Subsequently, N,N-dimethylformamide (2.0 g, 28 mmol) was added to the reaction system and stirring was continued at -78 °C for 30 min. After completion of the reaction, the reaction was quenched by adding water to the reaction mixture and extracted with ethyl acetate. The organic phases were combined, washed sequentially with 1N hydrochloric acid and water, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=1:9) to give 3.0 g of 3-bromo-2,6-difluorobenzaldehyde in 32% yield. The melting point of the product was 53-54 °C. 1H-NMR (CDCl3) δ: 7.00 (1H, dt, J = 9.3,1.8 Hz), 7.71-7.82 (1H, m), 10.3 (1H, s).

References

[1] Patent: US2010/41891, 2010, A1. Location in patent: Page/Page column 62
[2] Patent: WO2015/89809, 2015, A1. Location in patent: Page/Page column 49; 50
[3] Patent: WO2015/95256, 2015, A1. Location in patent: Page/Page column 50

3-BROMO-2,6-DIFLUOROBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-BROMO-2,6-DIFLUOROBENZALDEHYDE manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 3-Bromo-2,6-difluorobenzaldehyde 398456-82-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-10-22

Career Henan Chemical Co

Product: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE 398456-82-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-02

398456-82-1, 3-BROMO-2,6-DIFLUOROBENZALDEHYDERelated Search:

2,6-Difluorobenzaldehyde 4-BROMO-2,6-DIFLUOROBENZALDEHYDE DIMETHYL ACETAL 6-BROMO-2,3-DIFLUOROBENZALDEHYDE 4-bromo-2,5-difluorobenzaldehyde 4-BROMO-2,3-DIFLUOROBENZALDEHYDE 4-BROMO-2,6-DIFLUOROBENZALDEHYDE 3-bromo-2,6-difluorobenzoic acid 3-BROMO-2,4,5-TRIFLUOROBENZOIC ACID 3-BROMO-2,6-DIFLUOROBENZALDEHYDE 2-BROMO-3-FLUOROBENZALDEHYDE 3-BROMO-2,4,5,6-TETRAFLUOROBENZOYL CHLORIDE 1-BROMO-2,4-DIFLUORO-3-METHYLBENZENE

3-BROMO-2,6-DIFLUOROBENZALDEHYDE

3-Bromo-2,6-difluorobenzaldehyde98%

3-Bromo-2,6-difluorobenzaldehyde 98%

Benzaldehyde, 3-bromo-2,6-difluoro-

3-BROMO-2,6-DIFLUOROBENZALDEHYDE ISO 9001：2015 REACH

398456-82-1