ChemicalBook > CAS DataBase List > GLYCOPROTEIN, ALPHA1-ACID HUMAN
GLYCOPROTEIN, ALPHA1-ACID HUMAN
- Product Name
- GLYCOPROTEIN, ALPHA1-ACID HUMAN
- CAS No.
- 66455-27-4
- Chemical Name
- GLYCOPROTEIN, ALPHA1-ACID HUMAN
- Synonyms
- AGP;PSKR;Phytosulfokine-α;PSK1;TAO1;ps-k;SEZ6L2;MAP3K17;OROSOMUCOID;C-AGP, HUMAN
- CBNumber
- CB4197265
- Molecular Formula
- NULL
- Formula Weight
- 0
- MOL File
- Mol file
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GLYCOPROTEIN, ALPHA1-ACID HUMAN Property
- storage temp.
- 2-8°C
- solubility
- H2O: 10 mg/mL, clear, colorless
- form
- Lyophilized
- biological source
- human plasma
- Merck
- 13,8018
- Specific Activity
- 88-120nmol/min·mg
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- T0328
- Product name
- TAOK2 (1-314), active, GST tagged human
- Purity
- PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
- Packaging
- 10μG
- Price
- $537
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- G3643
- Product name
- α1-Acid Glycoprotein from bovine plasma
- Purity
- 99%
- Packaging
- 25mg
- Price
- $325
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 112251
- Product name
- α?-Acid Glycoprotein, Human Plasma
- Packaging
- 1mg
- Price
- $144
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- G9885
- Product name
- α1-Acid Glycoprotein from human plasma
- Purity
- ≥99% (agarose gel electrophoresis)
- Packaging
- 5mg
- Price
- $97.8
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- G9885
- Product name
- α1-Acid Glycoprotein from human plasma
- Purity
- ≥99% (agarose gel electrophoresis)
- Packaging
- 10mg
- Price
- $196
- Updated
- 2025/07/31
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GLYCOPROTEIN, ALPHA1-ACID HUMAN Chemical Properties,Usage,Production
Chemical Properties
This product is brown or brownish powder, slightly peculiar odor, tasteless. Melting point 120℃. Soluble in water, almost insoluble in methanol, chloroform, benzene, cyclohexane and so on. This product is a kind of proteoglycan, protein content 25%-30%. It has anti-tumor activity both in vivo and in vitro. Its anti-tumor effect is related to its excitation of the body's anti-tumor immune function. Yunzhi polysaccharide can enhance the cellular immune function, and promote the delayed allergic reaction and lymphocyte proliferation reaction. It can also increase the production of interferon, interleukins 1 and 2 and prostaglandins. It can also normalize the low IgG and IgM of the tumor-bearing animals. In addition, it could not enhance the phagocytosis of macrophages in tumor-bearing animals. After oral administration, Yunzhi polysaccharide is absorbed from the digestive tract and distributed to organs and tumor tissues throughout the body, and about 70% of it is eliminated from the body within 24 h. It is mainly excreted in the form of carbon dioxide through the respiratory tract.
Uses
α1-Acid glycoprotein from human plasma has been used:
- as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers
- to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA
- to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors
Uses
GLYCOPROTEIN, ALPHA1-ACID HUMAN was used to study nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine.
General Description
α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family.
Biochem/physiol Actions
α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital.
Purification Methods
Purify the glycoprotein 1 acid by passage through a carboxymethyl cellulose column, then through a Sephadex G-25 column. [Aronson et al. J Biol Chem 243 4564 1968.]
GLYCOPROTEIN, ALPHA1-ACID HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
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