METHYLDIPHENYLPHOSPHINE

Product Name: METHYLDIPHENYLPHOSPHINE
CAS No.: 1486-28-8
Chemical Name: METHYLDIPHENYLPHOSPHINE
Synonyms: 98% (C6H5)2(CH3)P;Methyldiphenylphsphine;DIPHENYLMETHYLPHOSPHINE;METHYLDIPHENYLPHOSPHINE;Diphenylphosphinomethane;Methyldiphenylphosphine>Phosphine, methyldiphenyl-;Methyldiphenylphosphine 99%;Methyldiphenylphosphine,99%;Methyldiphenylphosphine, 99% 5GR
CBNumber: CB4239518
Molecular Formula: C13H13P
Formula Weight: 200.22
MOL File: 1486-28-8.mol

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METHYLDIPHENYLPHOSPHINE Property

Melting point:: 117-118 °C
Boiling point:: 120-122 °C1.5 mm Hg(lit.)
Density: 1.076 g/mL at 25 °C(lit.)
refractive index: n20/D 1.625(lit.)
Flash point:: >230 °F
storage temp.: Inert atmosphere,Room Temperature
form: Liquid
color: Clear colorless to slightly yellow
Specific Gravity: 1.076
Water Solubility: Insoluble in water.
Sensitive: Air Sensitive
BRN: 743075
InChI: InChI=1S/C13H13P/c1-14(12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11H,1H3
InChIKey: UJNZOIKQAUQOCN-UHFFFAOYSA-N
SMILES: P(C)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference: 1486-28-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 17-23-24/25-36/37/39-26
WGK Germany: 3
F: 1-10
TSCA: No
HS Code: 29420000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 244902
Product name: Methyldiphenylphosphine
Purity: 99%
Packaging: 1g
Price: $43.76
Updated: 2025/07/31

Sigma-Aldrich

Product number: 244902
Product name: Methyldiphenylphosphine
Purity: 99%
Packaging: 10g
Price: $128.7
Updated: 2025/07/31

TCI Chemical

Product number: M1318
Product name: Methyldiphenylphosphine
Purity: >97.0%(GC)
Packaging: 1g
Price: $63
Updated: 2025/07/31

TCI Chemical

Product number: M1318
Product name: Methyldiphenylphosphine
Purity: >97.0%(GC)
Packaging: 5g
Price: $146
Updated: 2025/07/31

Strem Chemicals

Product number: 15-3250
Product name: Methyldiphenylphosphine, 99%
Packaging: 5g
Price: $60
Updated: 2024/03/01

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METHYLDIPHENYLPHOSPHINE Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liqui

Uses

Methyldiphenylphosphine, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Application

Methyldiphenylphosphine is an important organophosphorus ligand widely used in catalytic chemistry and materials science. It often forms complexes with transition metals such as palladium, rhodium, and nickel as a monodentate ligand, catalyzing a variety of organic synthesis reactions, such as carbon-carbon coupling reactions (e.g., the Heck and Suzuki reactions), hydroformylation, and asymmetric hydrogenation, effectively enhancing the activity and selectivity of these reactions. Furthermore, due to its unique electronic and steric properties, it is also used in the synthesis of functional materials such as luminescent materials and liquid crystals, and as a protective agent for stabilizing nanoparticles, demonstrating its significant value in organic electronics and nanotechnology.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

Synthesis

The mainstream preparation method for methyldiphenylphosphine typically involves a nucleophilic substitution reaction between a Grignard reagent or an organolithium reagent and chlorodiphenylphosphine. The most common approach involves first preparing methylmagnesium bromide (CH₃MgBr) via a Grignard reaction, which is then added dropwise to a solution of chlorodiphenylphosphine in an inert solvent such as diethyl ether or tetrahydrofuran. After the reaction is complete, post-processing steps such as hydrolysis and extraction are performed to remove the byproduct magnesium chloride and unreacted starting materials. Finally, purification is performed by vacuum distillation or recrystallization to obtain the target product, methyldiphenylphosphine.

METHYLDIPHENYLPHOSPHINE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYLDIPHENYLPHOSPHINE Suppliers

Americas 1 Belgium 3 China 134 Europe 1 Germany 5 India 3 Japan 5 Russia 1 Switzerland 3 United Kingdom 6 United States 20 Global 182

Aladdin Scientific

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Prime Organics, Inc.

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View Lastest Price from METHYLDIPHENYLPHOSPHINE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: METHYLDIPHENYLPHOSPHINE 1486-28-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-06

Shaanxi Dideu Medichem Co. Ltd

Product: Methyldiphenylphosphine 1486-28-8
Price: US $1.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2020-01-16

Henan Bao Enluo International TradeCo.，LTD

Product: METHYLDIPHENYLPHOSPHINE 1486-28-8
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10000MT
Release date: 2023-08-08

1486-28-8, METHYLDIPHENYLPHOSPHINERelated Search:

1,6-Bis(diphenylphosphino)hexane 1,1'-Bis(diphenylphosphino)ferrocene Bis(diphenylphosphino)methane 1,4-Bis(diphenylphosphino)butane TETRAPHENYLPHOSPHINE IMIDE DIPHENYL(PENTAFLUOROPHENYL)PHOSPHINE METHYLDIPHENYLPHOSPHINE OXIDE BIS(2-DIPHENYLPHOSPHINOETHYL)PHENYLPHOSPHINE TRIPHENYLPHOSPHINE DIBROMIDE BIS(PENTAFLUOROPHENYL)PHENYLPHOSPHINE (FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE 1,5-Bis(diphenylphosphino)pentane 1,2-Bis(diphenylphosphino)ethane Triphenylphosphine oxide 1,3-Bis(diphenylphosphino)propane CIS-1,2-BIS(DIPHENYLPHOSPHINO)ETHYLENE TETRAKIS(METHYLDIPHENYLPHOSPHINE)PALLADIUM(0) (1,5-CYCLOOCTADIENE)BIS(METHYLDIPHENYLPHOSPHINE)IRIDIUM(I) HEXAFLUOROPHOSPHATE

METHYLDIPHENYLPHOSPHINE

DIPHENYLMETHYLPHOSPHINE

Methyldiphenylphsphine

Methyldiphenylphosphine,99%

Diphenylphosphinomethane

Methyldiphenylphosphine, 99% 25GR

Methyldiphenylphosphine, 99% 5GR

98% (C6H5)2(CH3)P

Methyldiphenylphosphine 99%

Methyldiphenylphosphine,98% (C6H5)2(CH3)P

Methyldiphenylphosphine&gt

Phosphine, methyldiphenyl-

1486-28-8

C6H52PCH3

C13H13P

CH3C6H52P

Phosphine Ligands

Catalysis and Inorganic Chemistry

Phosphorus Compounds

Achiral Phosphine

Aryl Phosphine

organophosphorus ligand

Ligand

Phosphine Ligands

Synthetic Organic Chemistry