ChemicalBook > CAS DataBase List > 2,6-Dichloronicotinonitrile

2,6-Dichloronicotinonitrile

Product Name
2,6-Dichloronicotinonitrile
CAS No.
40381-90-6
Chemical Name
2,6-Dichloronicotinonitrile
Synonyms
2,6-Dichloronicotino;oropyridine-3-carbonitriL;2,6-DICHLORONICOTINONITRILE;2,6-Dichloro-3-Cyanopyridine;2,6-dichloro-3-cyannopyridine;2,6- twochloro -3-cyanopyridine;2,6-Dichloronicotinonitrile 97%;2,6-Dichloro-3-cyanopyridine >2,6-Dichloro-pyridin-3-carbonitrile;2,6-Dichloropyridine-3-acetonitrile
CBNumber
CB4240189
Molecular Formula
C6H2Cl2N2
Formula Weight
173
MOL File
40381-90-6.mol
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2,6-Dichloronicotinonitrile Property

Melting point:
121-124 °C
Boiling point:
286.0±35.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
-5.33±0.10(Predicted)
color 
White to Light yellow
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C6H2Cl2N2/c7-5-2-1-4(3-9)6(8)10-5/h1-2H
InChIKey
LFCADBSUDWERJT-UHFFFAOYSA-N
SMILES
C1(Cl)=NC(Cl)=CC=C1C#N
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Safety

Hazard Codes 
T
Risk Statements 
25-41-37/38
Safety Statements 
26-39-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
Ⅲ
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
703079
Product name
2,6-Dichloropyridine-3-carbonitrile
Purity
97%
Packaging
1g
Price
$76
Updated
2023/06/20
Sigma-Aldrich
Product number
684872
Product name
2,6-Dichloropyridine-3-carbonitrile
Purity
97%
Packaging
1g
Price
$95.5
Updated
2022/05/15
TCI Chemical
Product number
D4650
Product name
2,6-Dichloro-3-cyanopyridine
Purity
>98.0%(GC)
Packaging
200mg
Price
$22
Updated
2025/07/31
TCI Chemical
Product number
D4650
Product name
2,6-Dichloro-3-cyanopyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$62
Updated
2025/07/31
TRC
Product number
D435658
Product name
2,6-Dichloronicotinonitrile
Packaging
250mg
Price
$55
Updated
2021/12/16
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2,6-Dichloronicotinonitrile Chemical Properties,Usage,Production

Chemical Properties

Brown yellow powder

Uses

2,6-Dichloro-3-cyanopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 2693, 1979 DOI: 10.1021/jo01329a020

Synthesis

76175-82-1

40381-90-6

General procedure for the synthesis of 2,6-dichloronicotinonitrile from N-(2,6-dichloropyridin-3-yl)acetamide: To a solution of dichloromethane (100 mL) containing 2,6-dichloro-3-acetamidopyridine (6.3 g, 55% purity) and pyridine (4.93 mL, 61 mmol) was slowly added trifluoroacetic anhydride (4.23 mL, 30 mmol). The reaction mixture was stirred overnight at room temperature and subsequently concentrated under reduced pressure. The crude product was purified by fast chromatography using 85% hexane and 15% ethyl acetate as eluents to give a light yellow product (1.77 g, 90% yield).HPLC analysis showed a retention time of 10.26 min (90% purity) and mass spectrometry analysis showed the molecular ion peak [M+H]+ = 172.9, and the theoretical molecular weight for the molecular formula C6H2Cl2N2 was 171.9 g/mol.

References

[1] Patent: US2002/156087, 2002, A1

2,6-Dichloronicotinonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,6-Dichloronicotinonitrile manufacturers

Dideu Industries Group Limited
Product
2,6-Dichloronicotinonitrile 40381-90-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-25

40381-90-6, 2,6-DichloronicotinonitrileRelated Search:

2-Chloro-5-chloromethylpyridine 3-Cyanopyridine 3-Hydroxypyridine 2,6-Lutidine Dichloroethane 3-Aminopyridine 2,6-Dichloropyridine DICHLOROISOCYANURIC ACID Clopyralid Quinclorac Diisopropylammonium dichloroacetate 2-Chloro-3-cyanopyridine Thionyl chloride Sodium dichloroisocyanurate Dichlorodimethylsilane 1,3-Dichloropropene 1,2-Dichloroethane N,N-Dimethylacetamide

  • 2,6-Dichloro-3-Cyanopyridine
  • 2,6-DICHLORONICOTINONITRILE
  • 2,6-Dichloropyridine-3-carbonitrile, 3-Cyano-2,6-dichloropyridine
  • 2,6-Dichloronicotino
  • 2, 6-dichloro-3-pyridinecarbonitrile
  • 2,6- twochloro -3-cyanopyridine
  • 2,6-Dichloro-pyridin-3-carbonitrile
  • 2,6-Dichloronicotinonitrile 97%
  • 2,6-Dichloro-3-cyanopyridine &gt
  • oropyridine-3-carbonitriL
  • 3-Pyridinecarbonitrile, 2,6-dichloro-
  • 2,6-Dichloronicotinonitrile ISO 9001：2015 REACH
  • 2,6-Dichloropyridine-3-acetonitrile
  • 2,6-Dichloronicotinonitrile, 96% (Custo
  • 2,6-dichloro-3-cyannopyridine
  • 40381-90-6
  • Heterocycle-Pyridine series
  • Halogenated Heterocycles
  • Heterocyclic Compounds