2,6-Dichloronicotinonitrile
- Product Name
- 2,6-Dichloronicotinonitrile
- CAS No.
- 40381-90-6
- Chemical Name
- 2,6-Dichloronicotinonitrile
- Synonyms
- 2,6-Dichloronicotino;oropyridine-3-carbonitriL;2,6-DICHLORONICOTINONITRILE;2,6-Dichloro-3-Cyanopyridine;2,6-dichloro-3-cyannopyridine;2,6- twochloro -3-cyanopyridine;2,6-Dichloronicotinonitrile 97%;2,6-Dichloro-3-cyanopyridine >2,6-Dichloro-pyridin-3-carbonitrile;2,6-Dichloropyridine-3-acetonitrile
- CBNumber
- CB4240189
- Molecular Formula
- C6H2Cl2N2
- Formula Weight
- 173
- MOL File
- 40381-90-6.mol
2,6-Dichloronicotinonitrile Property
- Melting point:
- 121-124 °C
- Boiling point:
- 286.0±35.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- -5.33±0.10(Predicted)
- color
- White to Light yellow
- Sensitive
- Moisture Sensitive
- InChI
- InChI=1S/C6H2Cl2N2/c7-5-2-1-4(3-9)6(8)10-5/h1-2H
- InChIKey
- LFCADBSUDWERJT-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC(Cl)=CC=C1C#N
Safety
- Hazard Codes
- T
- Risk Statements
- 25-41-37/38
- Safety Statements
- 26-39-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 703079
- Product name
- 2,6-Dichloropyridine-3-carbonitrile
- Purity
- 97%
- Packaging
- 1g
- Price
- $76
- Updated
- 2023/06/20
- Product number
- 684872
- Product name
- 2,6-Dichloropyridine-3-carbonitrile
- Purity
- 97%
- Packaging
- 1g
- Price
- $95.5
- Updated
- 2022/05/15
- Product number
- D4650
- Product name
- 2,6-Dichloro-3-cyanopyridine
- Purity
- >98.0%(GC)
- Packaging
- 200mg
- Price
- $22
- Updated
- 2025/07/31
- Product number
- D4650
- Product name
- 2,6-Dichloro-3-cyanopyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $62
- Updated
- 2025/07/31
- Product number
- D435658
- Product name
- 2,6-Dichloronicotinonitrile
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
2,6-Dichloronicotinonitrile Chemical Properties,Usage,Production
Chemical Properties
Brown yellow powder
Uses
2,6-Dichloro-3-cyanopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis Reference(s)
The Journal of Organic Chemistry, 44, p. 2693, 1979 DOI: 10.1021/jo01329a020
Synthesis
76175-82-1
40381-90-6
General procedure for the synthesis of 2,6-dichloronicotinonitrile from N-(2,6-dichloropyridin-3-yl)acetamide: To a solution of dichloromethane (100 mL) containing 2,6-dichloro-3-acetamidopyridine (6.3 g, 55% purity) and pyridine (4.93 mL, 61 mmol) was slowly added trifluoroacetic anhydride (4.23 mL, 30 mmol). The reaction mixture was stirred overnight at room temperature and subsequently concentrated under reduced pressure. The crude product was purified by fast chromatography using 85% hexane and 15% ethyl acetate as eluents to give a light yellow product (1.77 g, 90% yield).HPLC analysis showed a retention time of 10.26 min (90% purity) and mass spectrometry analysis showed the molecular ion peak [M+H]+ = 172.9, and the theoretical molecular weight for the molecular formula C6H2Cl2N2 was 171.9 g/mol.
References
[1] Patent: US2002/156087, 2002, A1
2,6-Dichloronicotinonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Dichloronicotinonitrile Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 2,6-Dichloronicotinonitrile manufacturers
- Product
- 2,6-Dichloronicotinonitrile 40381-90-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-25