Uses
ChemicalBook > CAS DataBase List > 3-BroMo-5fluoro-4-Methylpyridine

3-BroMo-5fluoro-4-Methylpyridine

Uses
Product Name
3-BroMo-5fluoro-4-Methylpyridine
CAS No.
1211517-76-8
Chemical Name
3-BroMo-5fluoro-4-Methylpyridine
Synonyms
3-BroMo-5fluoro-4-Methylpyridine;Pyridine, 3-bromo-5-fluoro-4-methyl-;3-BroMo-5fluoro-4-Methylpyridine ISO 9001：2015 REACH
CBNumber
CB42549967
Molecular Formula
C6H5BrFN
Formula Weight
190.01
MOL File
1211517-76-8.mol
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3-BroMo-5fluoro-4-Methylpyridine Property

Boiling point:
183.5±35.0 °C(Predicted)
Density 
1.592±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
1.11±0.28(Predicted)
form 
liquid
color 
Clear, colourless
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B692658
Product name
3-Bromo-5-fluoro-4-methylpyridine
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
B692658
Product name
3-Bromo-5-fluoro-4-methylpyridine
Packaging
1g
Price
$260
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0364552
Product name
3-BROMO-5-FLUORO-4-METHYLPYRIDINE
Purity
95.00%
Packaging
5MG
Price
$499.2
Updated
2021/12/16
Apolloscientific
Product number
PC201059
Product name
3-Bromo-5-fluoro-4-methylpyridine
Purity
95%
Packaging
1g
Price
$73
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-B-3S
Product name
3-Bromo-5-fluoro-4-methylpyridine
Purity
95%
Packaging
1g
Price
$117
Updated
2021/12/16
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3-BroMo-5fluoro-4-Methylpyridine Chemical Properties,Usage,Production

Uses

3-Bromo-5-fluoro-4-methylpyridine is a heterocyclic organic compound that can be used as an organic chemical intermediate and can be obtained by methylation of 3-bromo-5-fluoropyridine.

Synthesis

407-20-5

74-88-4

1211517-76-8

Step 1: Dissolve 3-bromo-5-fluoropyridine (5.0 g, 28.4 mmol) in anhydrous THF (23 mL) at -78 °C and slowly dropwise add LDA (2M solution of cyclohexane/ethylphenol THF, 21.3 mL, 42.6 mmol) to the solution of anhydrous THF (23 mL), with the dropwise addition time being controlled to be within 10 minutes. After dropwise addition, stirring was continued at -78 °C for 30 min. Subsequently, a solution of anhydrous THF (23 mL) in iodomethane (2.6 mL, 42.6 mmol) was slowly added dropwise, and after completion of dropwise addition, stirring was continued at -78 °C for 30 min. The reaction mixture was warmed to room temperature and stirred for 2 h. Upon completion of the reaction, the reaction was quenched with saturated NaHCO3 solution. NH4Cl solution was added and after stirring for 30 minutes at room temperature, the reaction mixture was extracted with EtOAc. The organic layers were combined, dried and concentrated under reduced pressure, and the residue was purified by column chromatography (SiO2, EtOAc/cyclohexane) to afford the target product 3-bromo-4-methyl-5-fluoropyridine (3.6 g, 66% yield).

References

[1] Patent: WO2015/22073, 2015, A1. Location in patent: Page/Page column 49
[2] Patent: US2013/109720, 2013, A1. Location in patent: Paragraph 0092; 0093
[3] Patent: WO2012/12478, 2012, A1. Location in patent: Page/Page column 48-49
[4] Patent: WO2012/148808, 2012, A1. Location in patent: Page/Page column 49
[5] Patent: WO2013/43520, 2013, A1. Location in patent: Page/Page column 36

3-BroMo-5fluoro-4-Methylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BroMo-5fluoro-4-Methylpyridine Suppliers

China 66 India 1 United Kingdom 1 United States 8 Global 76
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
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United States
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Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
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Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
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58
United States Biological
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sales@advtechind.com
Country
United States
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Combi-Blocks Inc.
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sales@combi-blocks.com
Country
United States
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SynQuest Laboratories, Inc.
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Email
info@synquestlabs.com
Country
United States
ProdList
6871
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Matrix Scientific
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sales@matrixscientific.com
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United States
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AfferChem, Inc.
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United States
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View Lastest Price from 3-BroMo-5fluoro-4-Methylpyridine manufacturers

Dideu Industries Group Limited
Product
3-BroMo-5fluoro-4-Methylpyridine 1211517-76-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-23
Shaanxi Dideu Medichem Co. Ltd
Product
3-Bromo-5fluoro-4-Methylpyridine 1211517-76-8
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-12
Career Henan Chemical Co
Product
3-BroMo-5fluoro-4-Methylpyridine 1211517-76-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-25

1211517-76-8, 3-BroMo-5fluoro-4-MethylpyridineRelated Search:

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  • 3-BroMo-5fluoro-4-Methylpyridine
  • Pyridine, 3-bromo-5-fluoro-4-methyl-
  • 3-BroMo-5fluoro-4-Methylpyridine ISO 9001：2015 REACH
  • 1211517-76-8
  • 1211517-76-9