3'-Methylacetanilide Property

Melting point:

65-67 °C (lit.)

Boiling point:

303 °C (lit.)

Density 

1.1410

vapor pressure 

16 mm Hg ( 163 °C)

refractive index 

1.5279 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

alcohol: freely soluble(lit.)

form 

powder to crystal

pka

15.12±0.70(Predicted)

color 

White to Light gray to Light yellow

Merck 

14,74

Stability:

Stable. Incompatible with strong oxidizing agents.

CAS DataBase Reference

537-92-8(CAS DataBase Reference)

NIST Chemistry Reference

N-(3-Tolyl)acetic acid amide(537-92-8)

EPA Substance Registry System

m-Acetotoluidide (537-92-8)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

AN2875000

HS Code 

29242998

Toxicity

LD50 orl-mus: 1450 mg/kg TXAPA9 19,20,71

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

3'-Methylacetanilide Chemical Properties,Usage,Production

Chemical Properties

white crystalline solid

General Description

White solid.

Air & Water Reactions

Water insoluble.

Reactivity Profile

3'-Methylacetanilide is an amide. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 3'-Methylacetanilide emits toxic fumes of nitrogen oxides.

Fire Hazard

Flash point data for 3'-Methylacetanilide are not available; however, 3'-Methylacetanilide is probably combustible.

Safety Profile

Moderately toxic by ingestion. Seealso p-ACETOTOLUIDIDE. When heated todecomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise the toluidide from H2O, EtOH, aqueous EtOH or Et2O/pet ether (m 66o). UV: max 245nm (EtOH). [Beilstein 12 H 860, 12 I 400, 12 II 468, 12 III 1962, 12 IV 1823.]