Wnt Agonist

Product Name: Wnt Agonist
CAS No.: 853220-52-7
Chemical Name: Wnt Agonist
Synonyms: BML;-284;AMBMP;BML-284;CS-2376;Wnt Agonist;2-Amino-4-[3;Wnt agonist 1;Wnt Agonist I;BML-284 (BML 284
CBNumber: CB42750501
Molecular Formula: C19H18N4O3
Formula Weight: 350.37
MOL File: 853220-52-7.mol

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Wnt Agonist Property

Boiling point:: 623.4±65.0 °C(Predicted)
Density: 1.353±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble20mg/mL, clear
pka: 6.62±0.10(Predicted)
form: Yellowish sticky solid
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26-39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0698
Product name: CID 11210285 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $119
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0698
Product name: CID 11210285 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $386
Updated: 2024/03/01

Sigma-Aldrich

Product number: 681665
Product name: Wnt Agonist - CAS 853220-52-7 - Calbiochem
Purity: The Wnt Agonist, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
Packaging: 5mg
Price: $265
Updated: 2024/03/01

Cayman Chemical

Product number: 19903
Product name: Wnt Agonist I
Purity: ≥98%
Packaging: 5mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 19903
Product name: Wnt Agonist I
Purity: ≥98%
Packaging: 10mg
Price: $120
Updated: 2024/03/01

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Wnt Agonist Chemical Properties,Usage,Production

Uses

CID 11210285 hydrochloride has been used as a Wnt agonist.

Definition

ChEBI: N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine is a member of pyrimidines.

Biological Activity

wnt agonist 1 is a small-molecule agonist of wnt signaling pathway [1].the wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation [1].wnt agonist 1 is a cell-permeable wnt signaling pathway agonist. wnt agonist 1 induced b-catenin- and tcf-dependent transcriptional activity in a dose-dependent way with ec50 of 0.7 μm. in xenopus embryos, treatment with wnt agonist 1 (10 μm) from developmental stage 10.5 to stage 40 resulted in substantial head defects, such as diminished heads and complete loss of eyes, and reduced eyes and heads. this phenotype is similar to that which results from wnt over-expression in head specification during early embryonic development.

Biochem/physiol Actions

CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β. CID 11210285is a Wnt agonist.

References

liu j, wu x, mitchell b, et al. a small-molecule agonist of the wnt signaling pathway. angew chem int ed engl. 2005 mar 18;44(13):1987-90.

Wnt Agonist Preparation Products And Raw materials

Raw materials

Preparation Products

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Wnt Agonist Suppliers

China 66 India 1 United States 11 Global 78

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

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View Lastest Price from Wnt Agonist manufacturers

Career Henan Chemical Co

Product: Wnt Agonist 853220-52-7
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

853220-52-7, Wnt AgonistRelated Search:

Wnt Signaling Antibody Sampler Kit Wnt/β-Catenin Activated Targets Antibody Sampler Kit Trimethylamine hydrochloride Betaine hydrochloride Methylamine hydrochloride N,N-Dimethyloctylamine 2-Fluoro-N-(3-fluoro-5-pyridin-2-yl-benzoyl)-benzenesulfonhydrazine WY-14643 Wnt-C59 WWL229 WS3

AMBMP

CID 11210285 hydrochloride

N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine hydrochloride

Wnt Agonist

Wnt agonist 1

BML-284

2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine hydrochloride

Wnt agonist 1 (BML-284)

N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine

Wnt Agonist I

BML-284 (BML 284

CS-2376

Wnt Agonist - CAS 853220-52-7 - Calbiochem

Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem

BML-284 (Wnt agonist 1)

Wnt agonist 1 hydrochloride

2-Amino-4-[3

4-(methylenedioxy)benzylamino]-6-(3-methoxyphenyl)pyrimidine

BML-284;2-AMINO-4-[3;4-(METHYLENEDIOXY)BENZYLAMINO]-6-(3-METHOXYPHENYL)PYRIMIDINE

CID 11210285 HCL（BML-284 HCl）

-284

BML

2,4-Pyrimidinediamine, N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-

BML-284 HCl，Wnt Agonist

N-cadherin,E-cadherin,malformed phenotype,BML 284,Wnt,inhibit,AGS,BML284,BML-284,TCF,Inhibitor,cardiac defect,MNK45

853220-52-7