ChemicalBook > CAS DataBase List > Budralazine

Budralazine

Product Name
Budralazine
CAS No.
36798-79-5
Chemical Name
Budralazine
Synonyms
PTLZ;DJ-1461;Butrazine;Buterazine;BUDRALAZINE;1,2H-PHTHALAZONE;DIHYDROOXOPHTHALAZINE;Budralazine USP/EP/BP;1,2-DIHYDROPHTHALAZIN-1-ONE;1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
CBNumber
CB4282099
Molecular Formula
C14H16N4
Formula Weight
240.3
MOL File
36798-79-5.mol
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Budralazine Property

Melting point:
183-185 °C(lit.)
Boiling point:
373.02°C (rough estimate)
Density 
1.1506 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
9.54±0.70(Predicted)
color 
Light Yellow to Yellow
Stability:
Light Sensitive
CAS DataBase Reference
36798-79-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
TH9185000
Toxicity
LD50 in mice, rats (mg/kg): 1820, 620 orally; 4020, 3570 i.p. (Onodera)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B689515
Product name
Budralazine
Packaging
50mg
Price
$185
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001776
Product name
BUDRALAZINE
Purity
95.00%
Packaging
50MG
Price
$329.7
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18537
Product name
Budralazine
Packaging
25mg
Price
$1500
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001776
Product name
BUDRALAZINE
Purity
95.00%
Packaging
500MG
Price
$1963.5
Updated
2021/12/16
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Budralazine Chemical Properties,Usage,Production

Description

Budralazine is an antihypertensive agent which is somewhat less potent than structurally related hydralazine, and reportedly produces less tachycardia.

Originator

Daiichi (Japan)

Uses

Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.

Definition

ChEBI: Budralazine is a member of phthalazines.

Manufacturing Process

A mixture of 2.0 g of 1-hydrazinophthalazine hydrochloride, 1.1 g of mesityl oxide (isoproplyideneacetone) and 100 ml of ethanol, was refluxed for 3 hours. The reaction mixture was concentrated in vacuo and the residue was dissolved in water. The water solution was neutralized with sodium bicarbonate, salted out and the product was extracted with benzene. The benzene layer was passed through a comparatively short column of alumina and the solvent was removed. The residue was crystallized from ether to give 0.7 g of 1-(1,3-dimethyl-2-butenylidene) hydrazinophthalazine, melting point 131°-132°C.

brand name

BUTERAZINE

Therapeutic Function

Antihypertensive

Budralazine Preparation Products And Raw materials

Raw materials

Preparation Products

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Budralazine Suppliers

Canada 1 China 33 Czech 1 Europe 1 France 1 India 2 Japan 2 Ukraine 1 United Kingdom 6 United States 18 Global 66
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19961
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
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58
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
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60
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
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30
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
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39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
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47
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
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80
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
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38
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
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Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
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Biddle Sawyer Corporation
Tel
--
Fax
--
Email
bsc@biddlesawyer.com
Country
United States
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Pfaltz & Bauer, Inc.
Tel
--
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sales@pfaltzandbauer.com
Country
United States
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Davos Chemical Corporation
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info@davos.com
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United States
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ChemPacific Corporation
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sales@chempacific.com
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United States
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6891
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Riedel-de Haen AG
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United States
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6773
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MP Biomedicals, Inc.
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United States
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6561
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Synchem Inc.
Tel
--
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Email
catalog@synchem.com
Country
United States
ProdList
1154
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View Lastest Price from Budralazine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Budralazine 36798-79-5
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-09

36798-79-5, BudralazineRelated Search:

Maleic acid 2,6-DIMETHYLNAPHTHALENE DBU 1,2-Dimethylhydrazine Dihydrochloride ETHANE Dimethyl phthalate Dimethyl sulfide Dimethyl ether Polybutene CIS-BUTENEDIOIC ANHYDRIDE Fumaric acid Dimethyl fumarate Dimethyl sulfoxide N,N-Dimethylformamide 3-BUTENE-1,2-DIOL Phthalazine Chrysene 1,2H-PHTHALAZONE,PHTHALAZONE

  • PTLZ
  • 1-(2-(1,3-DIMETHYL-2-BUTENYLIDENE)HYDRAZINO)PHTHALAZINE
  • 1,2-DIHYDROPHTHALAZIN-1-ONE
  • 1,2H-PHTHALAZONE
  • 1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
  • DIHYDROOXOPHTHALAZINE
  • BUDRALAZINE
  • 1-[2-(1,3-Dimethyl-2-buten-1-ylidene)hydrazino]phthalazine
  • 4-Methyl-3-penten-2-one (phthalazin-1-yl)hydrazone
  • Buterazine
  • DJ-1461
  • 1(2H)-Phthalazinone (1,3-DiMethyl-2-butenylidene)hydrazone
  • 4-Methyl-3-Penten-2-one 2-(1-phthalazinyl)hydrazone
  • Budralazine USP/EP/BP
  • 3-Penten-2-one, 4-methyl-, 2-(1-phthalazinyl)hydrazone
  • Butrazine
  • 36798-79-5
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