STACHYDRINE HYDROCHLORIDE

Product Name: STACHYDRINE HYDROCHLORIDE
CAS No.: 4136-37-2
Chemical Name: STACHYDRINE HYDROCHLORIDE
Synonyms: StachydrineHCl;Stachydrine chloride;Stachydrine hydrochL;Herba leonurl extract;Cadabine hydrochloride;Stachydrine hydrochlori;Stachydrine chloride-RM;Stachytine hydrochloride;Stachydrine hydrichloride;STACHYDRINE HYDROCHLORIDE
CBNumber: CB4290780
Molecular Formula: C7H14ClNO2
Formula Weight: 179.64
MOL File: 4136-37-2.mol

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STACHYDRINE HYDROCHLORIDE Property

Melting point:: 225°C
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
Water Solubility: Soluble in water
Merck: 14,8771
Stability:: Hygroscopic
CAS DataBase Reference: 4136-37-2(CAS DataBase Reference)

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Safety

Risk Statements: 20-22
Safety Statements: 22-45-36/37/39
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89799
Product name: Stachydrine chloride
Purity: phyproof? Reference Substance
Packaging: 25MG
Price: $286
Updated: 2024/03/01

TCI Chemical

Product number: S0358
Product name: Stachydrine Hydrochloride
Packaging: 10mg
Price: $31
Updated: 2024/03/01

Cayman Chemical

Product number: 20506
Product name: Stachydrine (hydrochloride)
Packaging: 100mg
Price: $63
Updated: 2024/03/01

Cayman Chemical

Product number: 20506
Product name: Stachydrine (hydrochloride)
Packaging: 1g
Price: $365
Updated: 2024/03/01

Cayman Chemical

Product number: 20506
Product name: Stachydrine (hydrochloride)
Packaging: 250mg
Price: $139
Updated: 2024/03/01

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STACHYDRINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Stachydrine Chloride is a constituent of the Chinese herb leonurus heterophyllus sweet. its used in clinics to support blood circulation and dispel blood stasis.

Biological Activity

stachydrine is an anti-metastatic agent.stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of c. leonurus, and many other asian plants and fruits.

in vitro

the aim of a previous study was to investigate the effects of stachydrine (sta) on norepinephrine (ne) induced hypertrophy and the changes of calcium transients in neonatal rat cardiomyocytes. results showed that ne treatment could increase protein synthesis, cell surface area, the expression level of β-mhc and β/α-mhc ratio and these effects were attenuated by sta treatment. in addition, ne-induced hypertrophy was associated with accelerated decay of ca2+-transient, increased phospholamban expression, increased ca2+-transient amplitude, hyper-phosphorylation, increased intracellular camp level, as well as pka overactivation. all of these effects could be inhibited by sta treatment significantly [1].

in vivo

previous study evaluated the effect of stachydrine on the expression of caspase-9 and 12 in rats with unilateral ureteral obstruction. results showed that degree of renal interstitial fibrosis, serum creatinine, blood urea nitrogen, the renal tubular interstitial damage index, and expression of caspase-9 and 12 in the stachydrine-treatment groups were significantly decreased [2].

target

IL Receptor | T-bet | RORγt | GATA-3 | Foxp3

References

[1] zhang, c. ,shan, x.-l.,liao, y.-l., et al. effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients. bmc complement. altern. med. 14, 474 (2014).
[2] zhang c, lu y, zhou yj, tong qq, qu c, kang tj. the effect of stachydrine on the expression of caspase-12 in rats with unilateral ureteral obstruction. j urol. 2014 nov;192(5):1549-54.

STACHYDRINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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STACHYDRINE HYDROCHLORIDE Suppliers

China 253 France 2 Germany 3 India 2 Japan 1 United Kingdom 8 United States 19 USA 1 Global 289

Pure Chemistry Scientific Inc.

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View Lastest Price from STACHYDRINE HYDROCHLORIDE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Stachydrine Hydrochloride 4136-37-2
Price: US $79.00-38.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-11-21

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Stachydrine hydrochloride 4136-37-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: ≥98% HPLC
Supply Ability: 1000KG
Release date: 2022-09-30

Hebei Yanxi Chemical Co., Ltd.

Product: Stachydrine hydrochloride 4136-37-2
Price: US $40.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-09-08

4136-37-2, STACHYDRINE HYDROCHLORIDERelated Search:

Evodiamine lithospermic acid B Schisandrin A Motherwort Herb P.E Motherwort Extract Betaine hydrochloride 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Berberine hydrochloride SANGUINARINE Ligustrazine Hydrochloride JATRORRHIZINE HCL(RG) Coptisine chloride CUCURBITACIN IIA 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole hydrochloride Pirenzepine hydrochloride Rimantadine hydrochloride FLUOXETINE HYDROCHLORIDE Robenidine hydrochloride

STACHYDRINE HYDROCHLORIDE

(S)-2-carboxy-1,1-dimethylpyrrolidinium chloride

StachydrineHCl

Stachydrine hydrichloride

2-Carboxy-1,1-dimethylpyrrolidinium chloride

Stachydrine chloride

Stachydrine hydrochlori

Stachydrine chloride 2-Carboxy-1,1-dimethylpyrrolidinium chloride

Stachydrine hydrochloride, froM Leonurus japonicus

Hydrochloric acid Stachydrine

Stachydrine hydrochloride, 98%, from Leonurus japonicus

Herba leonurl extract

Stachydrine hydrochloride, 98%, from Leonurus artemisia (Lour.) S. Y. Hu

Stachytine hydrochloride

Stachydrine hydrochL

Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride, (S)-

STACHYDRINE HYDROCHLORIDE CAS : 4136-37-2

(S)-2-Carboxy-1,1-dimethylpyrrolidin-1-ium chloride

Cadabine hydrochloride

Stachydrine chloride-RM

4136-37-2

C7H13NO2HCl

Ammonium Chlorides (Quaternary)

Quaternary Ammonium Compounds

Ammonium Chlorides (Quaternary)

Quaternary Ammonium Compounds