FILIPIN COMPLEX

Product Name: FILIPIN COMPLEX
CAS No.: 11078-21-0
Chemical Name: FILIPIN COMPLEX
Synonyms: FILIPIN;filmirisin;filimirasin;14-deoxylagosin;FILIPIN COMPLEX;FILIPIN COMPLEX USP/EP/BP;FILIPIN COMPLEX FROM STREPTOMYCES &;filipin complex from streptomyces filipinensis
CBNumber: CB4291136
Molecular Formula: C35H58O11
Formula Weight: 654.82842
MOL File: 11078-21-0.mol

More

Less

FILIPIN COMPLEX Property

Melting point:: 195-205°
alpha: D22 -148.3° (c = 0.89 in methanol)
storage temp.: −20°C
solubility: methanol: 10 mg/mL, clear, very dark yellow
form: powder
color: yellow
Merck: 13,4111

More

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: LK4400000
F: 10
HS Code: 2941900000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F9765
Product name: Filipin complex from Streptomyces filipinensis
Purity: ≥70% (UV)
Packaging: 25mg
Price: $212
Updated: 2024/03/01

Sigma-Aldrich

Product number: F9765
Product name: Filipin complex from Streptomyces filipinensis
Purity: ≥70% (UV)
Packaging: 50mg
Price: $388
Updated: 2024/03/01

Cayman Chemical

Product number: 25073
Product name: Filipin Complex
Purity: ≥95%
Packaging: 5mg
Price: $60
Updated: 2024/03/01

Cayman Chemical

Product number: 25073
Product name: Filipin Complex
Purity: ≥95%
Packaging: 25mg
Price: $148
Updated: 2024/03/01

ChemScene

Product number: CS-0064593
Product name: Filipincomplex
Purity: >97.0%
Packaging: 50mg
Price: $280
Updated: 2021/12/16

More

Less

FILIPIN COMPLEX Chemical Properties,Usage,Production

Uses

Filipin complex comprises a family of pentaene macrocyclic lactones first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Filipin complex consists of four analogues, with filipin III comprising the bulk (>70%) of the complex. Filipin complex is a potent broad spectrum antifungal agent that also exhibits antitumor and antiviral activities. Filipin complex acts by binding cell membrane sterols, disrupting membrane integrity.

Uses

Filipin complex from Streptomyces filipinensis has been used as a profluorescence probe to detect the free cholesterol in cell.

Definition

ChEBI: Filipin III is a macrolide that is the major component of a mixture of four isomeric polyene macrolides isolated from Streptomyces filipinensis. It has a role as a bacterial metabolite and a fluorescent probe. It is a macrolide, a polyol and an olefinic compound.

General Description

Chemical structure: macrolide

Biochem/physiol Actions

Filipin is a polyene macrolide antibiotic and antifungal. The antifungal mechanism of action is unclear but may be due to altering membrane permeability. Filipin binds to model crystalline phase lipid bilayers containing cholesterol, and to liquid phase bilayers with or without cholesterol, in an orientation that forms membrane pores.It both inhibits prion protein (PrP) endocytosis and causes the release of PrP from the plasma membrane.

FILIPIN COMPLEX Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

FILIPIN COMPLEX Suppliers

China 44 Germany 1 India 1 Switzerland 1 United Kingdom 1 United States 7 Global 55

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4554
Advantage: 62

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4674
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

More

Less

View Lastest Price from FILIPIN COMPLEX manufacturers

Career Henan Chemical Co

Product: FILIPINCOMPLEX 11078-21-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: KG/T
Release date: 2019-12-17

11078-21-0, FILIPIN COMPLEXRelated Search:

TERT-BUTYL ISOCYANIDE Ethyl isocyanoacetate Tosylmethyl isocyanide Tris(2,4-pentanedionato)chroMiuM(III) PHENYLSELENOL Cupric acetylacetonate Benzyl isocyanide Ferric acetylacetonate COBALT(II) ACETYLACETONATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 2,4-PENTANEDIONE, SILVER DERIVATIVE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) N-BUTYLISOCYANIDE Aluminum acetylacetonate METHYL ISOCYANOACETATE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)

14-deoxylagosin

filimirasin

filmirisin

FILIPIN

FILIPIN COMPLEX

filipin complex from streptomyces filipinensis

FILIPIN COMPLEX FROM STREPTOMYCES &

FILIPIN COMPLEX USP/EP/BP

11078-21-0

BioChemical

Antibiotics

Antibiotics A to Z

Antibiotics A-F

AntifungalPlasma&Blood Proteins

Filipin complexAntibiotics

MacrolidesApplication Index

Serum ProteinsMore...Close...

Antibiotics

Antibiotics A to

Antibiotics A-FAntibiotics

Chemical Structure Class

Interferes with Cell Membrane Permeability (Ionophores)Antibiotics

Mechanism of Action

Plasma, Blood, and Related Proteins and Reagents

Serum Proteins and Related Enzymes

Spectrum of Activity