ChemicalBook > CAS DataBase List > 3,4-Dimethoxyphenethylamine

3,4-Dimethoxyphenethylamine

Product Name
3,4-Dimethoxyphenethylamine
CAS No.
120-20-7
Chemical Name
3,4-Dimethoxyphenethylamine
Synonyms
HOMOVERATRYLAMINE;2-(3,4-Dimethoxyphenyl)ethanamine;DiMethoxyphenethylaMine;dmpea;Dimethoxyphenylethylamine;2-(3,4-DIMETHOXYPHENYL)ETHYLAMINE;Homoveratrile Amine;3,4-DIMETHOXY PHENYLETHYLAMINE;3,4- twoMethoxy phenylethylaMine;2-(3,4-DiMethoxyphenyl)-1-aMinoethane
CBNumber
CB4294076
Molecular Formula
C10H15NO2
Formula Weight
181.23
MOL File
120-20-7.mol
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3,4-Dimethoxyphenethylamine Property

Melting point:
12-15 °C
Boiling point:
188 °C15 mm Hg(lit.)
Density 
1.074 g/mL at 25 °C(lit.)
vapor pressure 
0.348-0.348Pa at 25℃
refractive index 
n20/D 1.546(lit.)
Flash point:
>230 °F
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
9.74±0.10(Predicted)
form 
Viscous Liquid
Specific Gravity
1.10
color 
Clear light yellow to orange or slightly brownish
PH
11.4 (100g/l, H2O, 20℃)
explosive limit
0.1-1.7%(V)
Water Solubility 
SOLUBLE
Sensitive 
Air Sensitive
InChIKey
ANOUKFYBOAKOIR-UHFFFAOYSA-N
LogP
0.77
CAS DataBase Reference
120-20-7(CAS DataBase Reference)
NIST Chemistry Reference
Benzeneethanamine, 3,4-dimethoxy-(120-20-7)
EPA Substance Registry System
Benzeneethanamine, 3,4-dimethoxy- (120-20-7)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-36-37/39
RIDADR 
UN 2735
WGK Germany 
3
RTECS 
SH2300000
10
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29222900
Toxicity
mouse,LD50,intraperitoneal,181mg/kg (181mg/kg),Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D0678
Product name
Homoveratrylamine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
D0678
Product name
Homoveratrylamine
Purity
min. 98.0 %
Packaging
100G
Price
$143
Updated
2024/03/01
TCI Chemical
Product number
D0678
Product name
Homoveratrylamine
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$456
Updated
2024/03/01
TRC
Product number
H669540
Product name
Homoveratrylamine
Packaging
10g
Price
$70
Updated
2021/12/16
Usbiological
Product number
013260
Product name
Homoveratrylamine
Packaging
10g
Price
$312
Updated
2021/12/16
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3,4-Dimethoxyphenethylamine Chemical Properties,Usage,Production

Description

3,4-Dimethoxyphenylethylamine, also known as 3,4-DMPEA or DMPEA is an endogenous metabolite found in urine that belongs to both the phenethylamine and catecholamine families. DMPEA is an analogue of dopamine (3,4-dihydroxyphenethylamine), with a substitution of the hydroxy groups with methoxy groups. It is also structurally similar to mescaline (3,4,5-trimethoxyphenylethylamine) and occurs naturally alongside it in various species of cacti such as the San Pedro and Peruvian Torch. DMPEA received wide attention after it was proposed as a biomarker in schizophrenic patients urine, however later studies revealed that DMPEA is also excreted by non-schizophrenics. DMPEA has little known bioactivity, but it has some action as a monoamine oxidase inhibitor. It has also been shown to have neurotoxic effects, especially in the nigrostriatal system and among dopaminergic neurons. DMPEA appears to be an inhibitor of mitochondrial complex I.

Chemical Properties

3,4-Dimethoxyphenethylamine is clear yellowish oil

Occurrence

3,4-Dimethoxyphenethylamine is a natural product found in Pilosocereus leucocephalus, Vachellia rigidula, and Ototropis elegans with data available.

Uses

3,4-Dimethoxyphenethylamine is a methylated metabolite of Dopamine (D533780); a potent inhibitor of brain mitochondrial respiration used in Parkinson’s disease studies.

Uses

Precursor for the synthesis of isoquinolines.

Definition

ChEBI: An aromatic ether that is the derivative of 2-phenylethylamine with methoxy substituents at the 3- and 4-positions. It is an alkaloid isolated from the Cactaceae family.

Flammability and Explosibility

Not classified

Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify the amine by fractionation through an efficient column in an inert atmosphere as it is a relatively strong base. [Horner & Sturm Justus Liebigs Ann Chem 608 12819 1957, Jung et al. J Am Chem Soc 75 4664 1953.] The hydrochloride has m 152o, 154o, 156o (from EtOH, Me2CO or EtOH/Et2O), the picrate has m 165-167o(dec), and the 4-nitrobenzoyl derivative has m 147o [Buck J Am Chem Soc 55 2593 1933]. [Beilstein 13 H 800, 13 IV 2604.]

3,4-Dimethoxyphenethylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Dimethoxyphenethylamine Suppliers

Nanjing Haoxin Pharmaceutical Technology Co., Ltd
Tel
15151219790
Email
895190506@qq.com
Country
China
ProdList
30
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58
Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-82375886 13001715031
Fax
0531-82375893
Email
3517280075@qq.com
Country
China
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1306
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58
Shanghai Witofly Chemical Co. ,Ltd.
Tel
021-5063062 15300832537
Email
sales@witofly.com
Country
China
ProdList
1603
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55
Suizhou Jiake Biological Engineering Co., Ltd.
Tel
0722-3632989 18008664499
Fax
0722-3255139
Email
2286801987@qq.com
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China
ProdList
103
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Shanghai RC Chemicals Co. Ltd
Tel
17305617782 17305617782
Fax
86-21-50322176
Email
sales1@rcc.net.cn
Country
China
ProdList
344
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55
Henan Wanxiang Chemical Industry Co.,Ltd.
Tel
0371-56669001 13949088811
Fax
0371-56669008
Email
Sales@58chem.cn
Country
China
ProdList
285
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58
Gansu Songsheng Pharmaceutical Co. , Ltd.
Tel
13705130158
Email
sales@unitechemical.com
Country
China
ProdList
149
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58
Lianyungang Shenghe Biotechnology Co., Ltd.
Tel
0518-87108777 13585296001
Email
haizaofu@163.com
Country
China
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42
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58
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5902
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65
Suzhou Nordica Biopharma Co.,LTD
Tel
15150674956
Email
dannilee@nordicabio.com
Country
China
ProdList
88
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View Lastest Price from 3,4-Dimethoxyphenethylamine manufacturers

Speranza Chemical Co., Ltd.
Product
3,4-Dimethoxyphenylethylamine 120-20-7
Price
US $20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
300 Tons/ year
Release date
2019-12-25
Hebei Chuanghai Biotechnology Co,.LTD
Product
3,4-Dimethoxyphenethylamine 120-20-7
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Shanghai Joiny Pharmaceutical Co.,LTD
Product
3,4-Dimethoxyphenethylamine 120-20-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-06-05

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