ChemicalBook > CAS DataBase List > Trifluoroacetophenone

Trifluoroacetophenone

Product Name
Trifluoroacetophenone
CAS No.
434-45-7
Chemical Name
Trifluoroacetophenone
Synonyms
2,2,2-TRIFLUORO-1-PHENYLETHAN-1-ONE;2,2,2-TRIFLUOROACETOPHENONE;2,2,2-TRIFLUORO-1-PHENYLETHANONE;Trifluoromethyl phenyl ketone;NSC 42752;TRIFLUOROACETOPHENONE;TRIFLUOROACETYLBENZENE;2,2,2-Trifluoracetophenon;2,2,2-trifluroacetophenone;A,A,A-TRIFLUOROACETOPHENONE
CBNumber
CB4322186
Molecular Formula
C8H5F3O
Formula Weight
174.12
MOL File
434-45-7.mol
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Trifluoroacetophenone Property

Melting point:
-40 °C
Boiling point:
165-166 °C (lit.) 46-48 °C/14 mmHg (lit.)
Density 
1.24 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.458(lit.)
Flash point:
107 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate
form 
Liquid
Specific Gravity
1.240
color 
Clear colorless to yellow
Water Solubility 
PRACTICALLY INSOLUBLE
BRN 
1866286
InChIKey
KZJRKRQSDZGHEC-UHFFFAOYSA-N
CAS DataBase Reference
434-45-7(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 2,2,2-trifluoro-1-phenyl-(434-45-7)
EPA Substance Registry System
Ethanone, 2,2,2-trifluoro-1-phenyl- (434-45-7)
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Safety

Hazard Codes 
Xi,F
Risk Statements 
10-36/37/38
Safety Statements 
26-36-37/39-16
RIDADR 
UN 1224 3/PG 3
WGK Germany 
3
Hazard Note 
Corrosive/Lachrymatory
TSCA 
T
HazardClass 
3
PackingGroup 
III
HS Code 
29147090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
107840
Product name
2,2,2-Trifluoroacetophenone
Purity
99%
Packaging
5g
Price
$51.3
Updated
2025/07/31
Sigma-Aldrich
Product number
107840
Product name
2,2,2-Trifluoroacetophenone
Purity
99%
Packaging
25g
Price
$244
Updated
2025/07/31
TCI Chemical
Product number
T0848
Product name
2,2,2-Trifluoroacetophenone
Purity
>98.0%(GC)
Packaging
5g
Price
$47
Updated
2025/07/31
TCI Chemical
Product number
T0848
Product name
2,2,2-Trifluoroacetophenone
Purity
>98.0%(GC)
Packaging
25g
Price
$137
Updated
2025/07/31
Sigma-Aldrich
Product number
107840
Product name
2,2,2-Trifluoroacetophenone
Purity
99%
Packaging
100g
Price
$532
Updated
2025/07/31
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Trifluoroacetophenone Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLORLESS TO YELLOW LIQUID

Uses

2,2,2-Trifluoroacetophenone is a fluorinated acetophenone with inhibitory activity of acetylcholinesterase. 2,2,2-Trifluoroacetophenone was shown to have neuroprotective activity by inhibiting apoptosis in cerebellar granule neurons.

General Description

2,2,2-Trifluoroacetophenone is the starting material for the synthesis of f 3-trifluoromethyl-3-phenyldiazirine. It undergoes asymmetric reduction with optically active Grignard reagent to form 2,2,2-trifluoro-1-phenylethanol. It undergoes condensation with biphenyl, terphenyl, a mixture of biphenyl with terphenyl, phenyl ether and diphenoxybenzophenone to form new aromatic 3F polymers.

Trifluoroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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Trifluoroacetophenone Suppliers

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View Lastest Price from Trifluoroacetophenone manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Trifluoroacetophenone 434-45-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-06
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Trifluoroacetophenone 434-45-7
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-05
Henan Aochuang Chemical Co.,Ltd.
Product
Trifluoroacetophenone 434-45-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09

434-45-7, TrifluoroacetophenoneRelated Search:

3'-Fluoroacetophenone 3-Aminoacetophenone 4'-Hydroxyacetophenone 4-Fluoroacetophenone 2',4'-Dichloroacetophenone Acetophenone 4-Nitroacetophenone 4'-Bromoacetophenone 2-Bromoacetophenone 3-Nitroacetophenone 4'-(Trifluoromethyl)acetophenone Trifluoroacetamide Trifluoroacetic acid Trifluoroacetic anhydride Trifluoroacetamidine Trifluoroacetyl chloride 4'-METHYL-2,2,2-TRIFLUOROACETOPHENONE 4-Carboxy-alpha,alpha,alpha-trifluoroacetophenone

  • α,α,α-Trifluoroacetophenone, Phenyl trifluoromethyl ketone
  • 1-Phenyl-2,2,2-trifluoroethanone
  • alpha,alpha,alpha-Trifluoroacetophenone,99%
  • 2,2,2-Trifluoro-1-phenyl-1-ethanone
  • 2,2,2-trifluroacetophenone
  • NSC 42752
  • A,A,A-TRIFLUOROACETOPHENONE FOR SYNTHESI
  • 1-Phenyl-2,2,2-trifluoroethan-1-one
  • alpha,alpha,alpha-Trifluoroacetophenone, 99% 5GR
  • a,a,a-Trifluoroacetophenone for synthesis
  • A,A,A-TRIFLUOROACETOPHENONE
  • ALPHA,ALPHA,ALPHA-TRIFLUOROACETOPHENONE
  • 2,2,2-TRIFLUORO-1-PHENYLETHANONE
  • 2,2,2-TRIFLUORO-1-PHENYLETHAN-1-ONE
  • 2,2,2-TRIFLUOROACETOPHENONE
  • 1,1,1-Trifluoroacetophenone
  • Phenyl trifluoromethyl ketone~2,2,2-Trifluoroacetophenone
  • alpha,alpha,alpha-Trifluoroacethophenone
  • Ethanone, 2,2,2-trifluoro-1-phenyl- (9CI)
  • Ethanone, 2,2,2-trifluoro-1-phenyl-
  • 2,2,2-Trifluoroacetophenone 99%
  • 2,2,2-Trifluoroacetophenone99%
  • PHENYL TRIFLUOROMETHYL KETONE
  • TRIFLUOROACETOPHENONE
  • TRIFLUOROACETYLBENZENE
  • 2,2,2-Trifluoro-1-phenylethanoate
  • 2,2,2-trifluoro-1-phenyl-ethanon
  • Acetophenone, 2,2,2-trifluoro-
  • Ethanone, 1,1,1-trifluoro,2-phenyl-
  • omega,omega,omega-Trifluoroacetophenone
  • Trifluoromethyl phenyl ketone
  • 2,2,2-Trifluoroacetophenone &gt
  • 2,2,2-Trifluoroacetophenone, 99%, for synthesis
  • 2,2,2-Trifluoro-1-Phenylethanone,98%
  • 2,2,2-Trifluoracetophenon
  • 2-Fluoro-4,6-dimethoxybenzoic acid
  • Trifluoroacetophenone 2,2,2-trifluroacetophenone,Ethanone, 2,2,2-trifluoro-1-phenyl-,2,2,2-Trifluoro-1-Phenylethanone,PHENYL TRIFLUOROMETHYL
  • 2,2,2-Trifluoroacetophenone, 98%
  • α,α,α-Trifluorobenzophenone
  • 434-45-7
  • CF3COC6H5
  • Building Blocks
  • Carbonyl Compounds
  • C7 to C8
  • Organic Building Blocks
  • Ketones
  • Aromatic Acetophenones & Derivatives (substituted)
  • ketone
  • ACETYLHALIDE