3,4-METHYLENEDIOXYPHENYLBORONIC ACID
- Product Name
- 3,4-METHYLENEDIOXYPHENYLBORONIC ACID
- CAS No.
- 94839-07-3
- Chemical Name
- 3,4-METHYLENEDIOXYPHENYLBORONIC ACID
- Synonyms
- BENZO[D][1,3]DIOXOL-5-YLBORONIC ACID;1,3-BENZODIOXOL-5-YLBORONIC ACID;enedioxy)phenyL;TIMTEC-BB SBB003898;RARECHEM AH PB 0145;3,4-Methylenedioxyphenylboroni;1,3-Benzodioxole-5-boronic acid;1,3-Benzodioxole-5-boronic acid 98%;3,4-METHYLENEDIOXYPHENYLBORONIC ACID;Boronic acid, B-1,3-benzodioxol-5-yl-
- CBNumber
- CB4379973
- Molecular Formula
- C7H7BO4
- Formula Weight
- 165.94
- MOL File
- 94839-07-3.mol
3,4-METHYLENEDIOXYPHENYLBORONIC ACID Property
- Melting point:
- 224-229 °C(lit.)
- Boiling point:
- 347.3±52.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 8.48±0.20(Predicted)
- form
- Powder
- color
- White to off-white
- BRN
- 5523347
- InChI
- InChI=1S/C7H7BO4/c9-8(10)5-1-2-6-7(3-5)12-4-11-6/h1-3,9-10H,4H2
- InChIKey
- CMHPUBKZZPSUIQ-UHFFFAOYSA-N
- SMILES
- B(C1=CC=C2OCOC2=C1)(O)O
- CAS DataBase Reference
- 94839-07-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 499994
- Product name
- 3,4-(Methylenedioxy)phenylboronic acid
- Purity
- ≥95%
- Packaging
- 5g
- Price
- $94
- Updated
- 2022/05/15
- Product number
- M2035
- Product name
- 3,4-(Methylenedioxy)phenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $87
- Updated
- 2025/07/31
- Product number
- M2035
- Product name
- 3,4-(Methylenedioxy)phenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 25g
- Price
- $305
- Updated
- 2025/07/31
- Product number
- M304408
- Product name
- 3,4-(Methylenedioxy)phenylboronic acid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 011004
- Product name
- 3,4-(Methylenedioxy)benzeneboronicacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
3,4-METHYLENEDIOXYPHENYLBORONIC ACID Chemical Properties,Usage,Production
Chemical Properties
3,4-METHYLENEDIOXYPHENYLBORONIC ACID is white powder
Uses
Reactant involved in:• ;Petasis reaction between glyoxylic acid, α-amino phosphonates, and organylboronic acids1• ;Mannich-type multicomponent assembly and 1,3-dipolar cycloaddition for synthesis of tetrahydroisoquinoline fused isoxazolidine scafford2• ;Suzuki-Miyaura cross-coupling of aryl and heteroaryl halides3,4• ;Oxidative Heck reaction for synthesis of functionalized cinnamaldehyde derivatives5• ;Intramolecular Alder-ene and Pictet-Spengler reactions for synthesis of crinine6
Uses
suzuki reaction
Uses
Reactant involved in:
- Petasis reaction between glyoxylic acid, α-amino phosphonates, and organylboronic acids
- Mannich-type multicomponent assembly and 1,3-dipolar cycloaddition for synthesis of tetrahydroisoquinoline fused isoxazolidine scafford
- Suzuki-Miyaura cross-coupling of aryl and heteroaryl halides
- Oxidative Heck reaction for synthesis of functionalized cinnamaldehyde derivatives
- Intramolecular Alder-ene and Pictet-Spengler reactions for synthesis of crinine
Synthesis
2635-13-4
5419-55-6
94839-07-3
General procedure for the synthesis of benzo[d][1,3]dioxol-5-ylboronic acid from 4-bromo-1,2-methylenedioxybenzene and triisopropyl borate: In a 100 mL three-necked round-bottomed flask under nitrogen protection, 5-bromobenzo[d][1,3]dioxolene (2 g, 9.95 mmol, 1.00 eq.) and THF (20 mL) were added, and the flask was cooled to -78 °C. Butyl lithium (BuLi, 5.6 mL, 1.40 eq.) was slowly added dropwise, followed by triisopropyl borate (1.96 g, 14.00 mmol). The reaction mixture was stirred at -78 °C for 1 hour and then slowly warmed to room temperature and continued stirring for 4 hours. Upon completion of the reaction, the reaction was quenched with 10 mL of water and acidified with sulfuric acid (4.9 g, 50.00 mmol, 5.00 equiv). The mixture was heated to reflux overnight. After cooling, it was extracted with ethyl acetate (3 x 50 mL), the organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting solid was washed with ethyl acetate (3 x 3 mL) to give 0.5 g (30% yield) of benzo[d][1,3]dioxol-5-ylboronic acid as a white solid.
References
[1] Patent: US2014/128392, 2014, A1. Location in patent: Paragraph 0311; 0312
3,4-METHYLENEDIOXYPHENYLBORONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
3,4-METHYLENEDIOXYPHENYLBORONIC ACID Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 3,4-METHYLENEDIOXYPHENYLBORONIC ACID manufacturers
- Product
- 1,3-Benzodioxol-5-ylboronic acid 94839-07-3
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-07-03
- Product
- 3,4-METHYLENEDIOXYPHENYLBORONIC ACID 94839-07-3
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10
- Release date
- 2024-08-19
- Product
- 3,4-Methylenedioxyphenyl boronic acid 94839-07-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- kgs
- Release date
- 2023-01-03