ChemicalBook > CAS DataBase List > 3,4-METHYLENEDIOXYPHENYLBORONIC ACID

3,4-METHYLENEDIOXYPHENYLBORONIC ACID

Product Name: 3,4-METHYLENEDIOXYPHENYLBORONIC ACID
CAS No.: 94839-07-3
Chemical Name: 3,4-METHYLENEDIOXYPHENYLBORONIC ACID
Synonyms: BENZO[D][1,3]DIOXOL-5-YLBORONIC ACID;1,3-BENZODIOXOL-5-YLBORONIC ACID;enedioxy)phenyL;TIMTEC-BB SBB003898;RARECHEM AH PB 0145;3,4-Methylenedioxyphenylboroni;1,3-Benzodioxole-5-boronic acid;1,3-Benzodioxole-5-boronic acid 98%;3,4-METHYLENEDIOXYPHENYLBORONIC ACID;Boronic acid, B-1,3-benzodioxol-5-yl-
CBNumber: CB4379973
Molecular Formula: C7H7BO4
Formula Weight: 165.94
MOL File: 94839-07-3.mol

Less

3,4-METHYLENEDIOXYPHENYLBORONIC ACID Property

Melting point:: 224-229 °C(lit.)
Boiling point:: 347.3±52.0 °C(Predicted)
Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 8.48±0.20(Predicted)
form: Powder
color: White to off-white
BRN: 5523347
InChI: InChI=1S/C7H7BO4/c9-8(10)5-1-2-6-7(3-5)12-4-11-6/h1-3,9-10H,4H2
InChIKey: CMHPUBKZZPSUIQ-UHFFFAOYSA-N
SMILES: B(C1=CC=C2OCOC2=C1)(O)O
CAS DataBase Reference: 94839-07-3(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29163990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 499994
Product name: 3,4-(Methylenedioxy)phenylboronic acid
Purity: ≥95%
Packaging: 5g
Price: $94
Updated: 2022/05/15

TCI Chemical

Product number: M2035
Product name: 3,4-(Methylenedioxy)phenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 5g
Price: $87
Updated: 2025/07/31

TCI Chemical

Product number: M2035
Product name: 3,4-(Methylenedioxy)phenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 25g
Price: $305
Updated: 2025/07/31

TRC

Product number: M304408
Product name: 3,4-(Methylenedioxy)phenylboronic acid
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Oakwood

Product number: 011004
Product name: 3,4-(Methylenedioxy)benzeneboronicacid
Purity: 97%
Packaging: 1g
Price: $10
Updated: 2021/12/16

Less

3,4-METHYLENEDIOXYPHENYLBORONIC ACID Chemical Properties,Usage,Production

Chemical Properties

3,4-METHYLENEDIOXYPHENYLBORONIC ACID is white powder

Uses

Reactant involved in:• ;Petasis reaction between glyoxylic acid, α-amino phosphonates, and organylboronic acids1• ;Mannich-type multicomponent assembly and 1,3-dipolar cycloaddition for synthesis of tetrahydroisoquinoline fused isoxazolidine scafford2• ;Suzuki-Miyaura cross-coupling of aryl and heteroaryl halides3,4• ;Oxidative Heck reaction for synthesis of functionalized cinnamaldehyde derivatives5• ;Intramolecular Alder-ene and Pictet-Spengler reactions for synthesis of crinine6

Uses

suzuki reaction

Uses

Reactant involved in:

Petasis reaction between glyoxylic acid, α-amino phosphonates, and organylboronic acids
Mannich-type multicomponent assembly and 1,3-dipolar cycloaddition for synthesis of tetrahydroisoquinoline fused isoxazolidine scafford
Suzuki-Miyaura cross-coupling of aryl and heteroaryl halides
Oxidative Heck reaction for synthesis of functionalized cinnamaldehyde derivatives
Intramolecular Alder-ene and Pictet-Spengler reactions for synthesis of crinine

Synthesis

2635-13-4

5419-55-6

94839-07-3

General procedure for the synthesis of benzo[d][1,3]dioxol-5-ylboronic acid from 4-bromo-1,2-methylenedioxybenzene and triisopropyl borate: In a 100 mL three-necked round-bottomed flask under nitrogen protection, 5-bromobenzo[d][1,3]dioxolene (2 g, 9.95 mmol, 1.00 eq.) and THF (20 mL) were added, and the flask was cooled to -78 °C. Butyl lithium (BuLi, 5.6 mL, 1.40 eq.) was slowly added dropwise, followed by triisopropyl borate (1.96 g, 14.00 mmol). The reaction mixture was stirred at -78 °C for 1 hour and then slowly warmed to room temperature and continued stirring for 4 hours. Upon completion of the reaction, the reaction was quenched with 10 mL of water and acidified with sulfuric acid (4.9 g, 50.00 mmol, 5.00 equiv). The mixture was heated to reflux overnight. After cooling, it was extracted with ethyl acetate (3 x 50 mL), the organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting solid was washed with ethyl acetate (3 x 3 mL) to give 0.5 g (30% yield) of benzo[d][1,3]dioxol-5-ylboronic acid as a white solid.

References

[1] Patent: US2014/128392, 2014, A1. Location in patent: Paragraph 0311; 0312

3,4-METHYLENEDIOXYPHENYLBORONIC ACID Preparation Products And Raw materials

Raw materials

Trimethyl borate 4-Bromo-1,2-(methylenedioxy)benzene Tetrahydrofuran Magnesium

Preparation Products

Less

3,4-METHYLENEDIOXYPHENYLBORONIC ACID Suppliers

Americas 1 Belgium 2 China 180 Europe 1 France 1 Germany 6 India 8 Japan 3 Jordan 1 Switzerland 1 Ukraine 1 United Kingdom 11 United States 41 Global 257

Dafeng Newti Pharmaceutical Technology Co., Ltd.

Tel: 0512-65916026; 18015586221
Email: 2760994703@qq.com
Country: China
ProdList: 265
Advantage: 55

Yuzhou Enthalpy Carbon Pharmaceutical Technology Co. LTD

Tel: 19963477321; 19963477321
Fax: QQ:2041275825
Email: 2041275825@qq.com
Country: China
ProdList: 1447
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9309
Advantage: 66

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

skychemical Co.Ltd

Tel: 021-20958197 20965099
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 1183
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4378
Advantage: 65

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 3997
Advantage: 55

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

Candia Thamtech Company Limited

Tel: 0371-86615086 18203638366 0371-86159066 13526786601
Fax: 0371-86159066
Country: China
ProdList: 2015
Advantage: 60

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

AllyChem Co., Ltd.

Tel: 0411-62313318 13942603642
Fax: 0411-87549748
Email: info@allychem.com
Country: China
ProdList: 1028
Advantage: 65

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 0371-0371-13526885213 15637198702
Fax: 0371-63709726
Email: hsyykjchem@163.com
Country: China
ProdList: 3852
Advantage: 58

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
Advantage: 60

Shanghai Boka-chem Tech. Inc.

Tel: 400-026-1533/(021) 6478-0600
Fax: +86 (21) 6459-2060
Email: sales@bokachem.com
Country: China
ProdList: 876
Advantage: 58

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Shanghai Rong Lin Medical Technology Co., Ltd.

Tel: 18602194589
Email: lincy-110@163.com
Country: China
ProdList: 863
Advantage: 58

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Chengdu Research Accelerators Technology Co., Ltd.

Tel: 028-64353063
Fax: 028-64353063 QQ:784253935
Email: reacchemical@163.com
Country: China
ProdList: 5253
Advantage: 58

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Wuhan Chemwish Technology Co.， Ltd

Tel: 027-67849912
Fax: 027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 9148
Advantage: 60

Less

View Lastest Price from 3,4-METHYLENEDIOXYPHENYLBORONIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1,3-Benzodioxol-5-ylboronic acid 94839-07-3
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-07-03

Shaanxi Dideu Medichem Co. Ltd

Product: 3,4-METHYLENEDIOXYPHENYLBORONIC ACID 94839-07-3
Price: US $0.10/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10
Release date: 2024-08-19

Capot Chemical Co.,Ltd.

Product: 3,4-Methylenedioxyphenyl boronic acid 94839-07-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: kgs
Release date: 2023-01-03

94839-07-3, 3,4-METHYLENEDIOXYPHENYLBORONIC ACIDRelated Search:

3,4-METHYLENEDIOXYPHENYLBORONIC ACID, PINACOL ESTER 9-phenanthrenylboronic acid 2,3-METHYLENEDIOXYPHENYLBORONIC ACID 3-Hydroxyphenylboronic acid 4-Hydroxyphenylboronic acid 3,4-METHYLENEDIOXYPHENYLBORONIC ACID 3-Methoxyphenylboronic acid 2,2-Difluoro-benzo[1,3]dioxole-5-boronic acid 2-FORMYL-4,5-METHYLENEDIOXYPHENYLBORONIC ACID

BENZO[D][1,3]DIOXOL-5-YLBORONIC ACID

RARECHEM AH PB 0145

TIMTEC-BB SBB003898

3,4-METHYLENEDIOXYBENZENEBORONIC ACID

3,4-METHYLENEDIOXYPHENYLBORONIC ACID

1,3-BENZODIOXOL-5-YLBORONIC ACID

1,3-Benzodioxole-5-boronic acid

3,4-Methylenedioxyphenylboroni

3,4-Methylenedioxyphenylboronic acid ,98%

3,4-(Methylenedioxy)phenylboronic Acid (contains varying amounts of Anhydride)

Boronic acid, B-1,3-benzodioxol-5-yl-

3,4-(Methylenedioxy)phenylboronic Acid&nbsp

3,4-Methylenedioxybenzeneboronic acid, 5-Borono-1,3-benzodioxole

(2H-1,3-benzodioxol-5-yl)boronic acid

1,3-Benzodioxole-5-boronic acid 98%

enedioxy)phenyL

3,4-(Methylenedioxy)BenzeneboronicAci

3,4-Methylenedioxyphenylboronic acid - [M4360]

94839-07-3

94839-04-3

BORONIC ACID

Organometallic Reagents

Aryl

Boronic Acids

Boronic Acids and Derivatives

Aryl Boronic Acids

Boronic Acids and Derivatives

Chemical Synthesis

Monosubstituted Aryl Boronic Acids

Organometallic Reagents

Boronic acids

Aryl

Boronic acid

Organoborons

Boronic Acids

Boronic Acids and Derivatives

blocks

BoronicAcids