VASICINONE
- Product Name
- VASICINONE
- CAS No.
- 486-64-6
- Chemical Name
- VASICINONE
- Synonyms
- VASICINONE;l-Vasicinone;Vasicinone-RM;2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one;(3R)-2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one;(3R)-2,3-Dihydro-3β-hydroxypyrrolo[2,1-b]quinazoline-9(1H)-one;Pyrrolo[2,1-b]quinazolin-9(1H)-one,2,3-dihydro-3-hydroxy-, (3S)-
- CBNumber
- CB4385271
- Molecular Formula
- C11H10N2O2
- Formula Weight
- 202.21
- MOL File
- 486-64-6.mol
VASICINONE Property
- Melting point:
- 200-202℃
- Boiling point:
- 320.7°C (rough estimate)
- Density
- 1.50
- refractive index
- 1.5300 (estimate)
- solubility
- Soluble in chloroform and ethanol;
- form
- powder
- pka
- 12.76±0.20(Predicted)
- color
- White
- Water Solubility
- 1.597g/L(25 ºC)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 11761
- Product name
- Vasicinone
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 11761
- Product name
- Vasicinone
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $161
- Updated
- 2024/03/01
- Product number
- 11761
- Product name
- Vasicinone
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $283
- Updated
- 2024/03/01
- Product number
- W1012
- Product name
- Vasicinone
- Packaging
- 10mg
- Price
- $413
- Updated
- 2021/12/16
- Product number
- CD32001262
- Product name
- Vasicinone
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $530
- Updated
- 2021/12/16
VASICINONE Chemical Properties,Usage,Production
Description
A further alkaloid present in Adhatoda vasica and Peganum harmala, this base forms colourless crystals from 95 per cent EtOH. It has [α]22D - 100° (c 0.5, CHCL3) and the ultraviolet spectrum has absorption maxima at 227, 272, 302 and 315 mfJ.. The alkaloid yields a series of crystalline salts with mineral acids, e.g. the hydrochloride, m.p. 232-4°C; hydro bromide, m.p. 254-5°C (dec.); hydriodide, m.p. 222-6°C (dec.); nitrate, m.p. 138-9° C (dec.) and the sulphate, m.p. l82-5°C (dec.). The optically inactive form of the base has been prepared synthetically, m.p. 211- 2°C. The alkaloid is an active bronchodilator.
Definition
ChEBI: Vasicinone is a member of quinazolines.
target
P450 (e.g. CYP17)
References
Ghose et al., J. Chem. Soc., 2740 (1932)
Morris, Horford, Adams., J. Amer. Chem. Soc., 57,951 (1935)
Mehta, Naravane, Desai., J. Org. Chem., 28, 445 (1963)
VASICINONE Preparation Products And Raw materials
Raw materials
Preparation Products
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