ChemicalBook > CAS DataBase List > 2,4-Dihydroxyacetophenone

2,4-Dihydroxyacetophenone

Product Name
2,4-Dihydroxyacetophenone
CAS No.
89-84-9
Chemical Name
2,4-Dihydroxyacetophenone
Synonyms
1-(2,4-dihydroxyphenyl)ethanone;Ethanone, 1-(2,4-dihydroxyphenyl)-;RESACETOPHENONE;2,4-DHAP;HyMechroMone;NSC 37559;NSC 10883;AKOS 90593;Resoacetophenone;4-Acetoresorcinol
CBNumber
CB4391766
Molecular Formula
C8H8O3
Formula Weight
152.15
MOL File
89-84-9.mol
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2,4-Dihydroxyacetophenone Property

Melting point:
143-144.5 °C(lit.)
Boiling point:
234.6°C (rough estimate)
Density 
1.18 g/mL at 25 °C(lit.)
refractive index 
1.4945 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
7.96±0.18(Predicted)
form 
Crystalline Powder or Crystals
color 
Off-white to pink to brown
PH
5 (1g/l, H2O, 20℃)
Sensitive 
Moisture Sensitive
Merck 
14,8140
BRN 
1282505
InChIKey
SULYEHHGGXARJS-UHFFFAOYSA-N
LogP
1.480 (est)
CAS DataBase Reference
89-84-9(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(2,4-dihydroxyphenyl)-(89-84-9)
EPA Substance Registry System
Ethanone, 1-(2,4-dihydroxyphenyl)- (89-84-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
2
RTECS 
AM7525000
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29145000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D107409
Product name
2′,4′-Dihydroxyacetophenone
Purity
99%
Packaging
100g
Price
$96.8
Updated
2025/07/31
Sigma-Aldrich
Product number
D107409
Product name
2′,4′-Dihydroxyacetophenone
Purity
99%
Packaging
500g
Price
$285
Updated
2025/07/31
TCI Chemical
Product number
D0561
Product name
2',4'-Dihydroxyacetophenone
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$47
Updated
2025/07/31
TCI Chemical
Product number
D0561
Product name
2',4'-Dihydroxyacetophenone
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$120
Updated
2025/07/31
TCI Chemical
Product number
D0561
Product name
2',4'-Dihydroxyacetophenone
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$462
Updated
2025/07/31
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2,4-Dihydroxyacetophenone Chemical Properties,Usage,Production

Chemical Properties

2,4-Dihydroxyacetophenone appears as a yellow-brown to reddish-brown fine crystalline powder. It slowly decomposes in water and can dissolve in hot alcohol, pyridine, and glacial acetic acid. In contrast, it is nearly insoluble in ether, benzene, and chloroform. A reaction with iron chloride causes it to adopt a red hue.

Uses

2,4-Dihydroxyacetophenone (cas# 89-84-9) is a compound useful in organic synthesis. It is also used as intermediate for pharmaceuticals. Reagent for iron as a 10% alcoholic solution. A red color is obtained with ferric ions in slightly acid solution: Cooper, Ind. Eng. Chem. Anal. Ed. 9, 334 (1937).

Definition

ChEBI: 2',4'-dihydroxyacetophenone is a dihydroxyacetophenone that is acetophenone carrying hydroxy substituents at positions 2' and 4'. It has a role as a plant metabolite. It is a member of resorcinols and a dihydroxyacetophenone.

Preparation

Preparation by reaction of acetic acid on resorcinol,
with zinc chloride (Nencki reaction) (94%)
with boron trifluoride
with Amberlite IR-120 (a cation exchange resin, sulfonic acid type) (87%)
with polyphosphoric acid (63%)
with 70% perchloric acid (33%).

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 428, 1948 DOI: 10.1021/ja01181a521

Safety Profile

Moderately toxic by ingestion. Experimental reproductive effects. A severe eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

2,4-Dihydroxyacetophenone is obtained by the acetylation of resorcinol and acetic acid. In addition, it can also be obtained by reacting resorcinol with chloroacetyl or acetic anhydride in the presence of zinc chloride.

target

Phospholipase (e.g. PLA)

2,4-Dihydroxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-Dihydroxyacetophenone Suppliers

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View Lastest Price from 2,4-Dihydroxyacetophenone manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2,4-Dihydroxyacetophenone 89-84-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-11
Hebei Chuanghai Biotechnology Co., Ltd
Product
2,4-Dihydroxyacetophenone 89-84-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 mt
Release date
2024-10-29
Hebei Zhuanglai Chemical Trading Co Ltd
Product
2,4-Dihydroxyacetophenone 89-84-9
Price
US $55.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-19

89-84-9, 2,4-DihydroxyacetophenoneRelated Search:


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