SPHINGOMYELINASE

Product Name: SPHINGOMYELINASE
CAS No.: 9031-54-3
Chemical Name: SPHINGOMYELINASE
Synonyms: EC 3.1.4.12;SPHINGOMYELINASE;Sphingomyelinase C;SPHINGOMYELIN PHOSPHODIESTERASE;sphingomyelinase from human placenta;SPHINGOMYELINASE FROM BACILLUS CEREUS;SPHINGOMYELINASE FROM STREPTOMYCES SP.;SPHINGOMYELIN CHOLINE PHOSPHOHYDROLASE;SPHINGOMYELINASE, STAPHYLOCOCCUS AUREUS;Native Bacillus cereus Sphingomyelinase
CBNumber: CB4393078
Formula Weight: 0
MOL File: Mol file

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SPHINGOMYELINASE Property

storage temp.: 2-8°C
form: lyophilized powder
color: White to off-white

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Safety

Hazard Codes: B
Safety Statements: 23-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S9396
Product name: Sphingomyelinase from Bacillus cereus
Purity: buffered aqueous glycerol solution, ≥100?units/mg protein (Lowry)
Packaging: 25units
Price: $227
Updated: 2024/03/01

Sigma-Aldrich

Product number: S9396
Product name: Sphingomyelinase from Bacillus cereus
Purity: buffered aqueous glycerol solution, ≥100?units/mg protein (Lowry)
Packaging: 50units
Price: $383
Updated: 2024/03/01

Sigma-Aldrich

Product number: S8633
Product name: Sphingomyelinase from Staphylococcus aureus
Purity: buffered aqueous glycerol solution, 100-300?units/mg protein (Lowry)
Packaging: 25units
Price: $215
Updated: 2024/03/01

Sigma-Aldrich

Product number: S8633
Product name: Sphingomyelinase from Staphylococcus aureus
Purity: buffered aqueous glycerol solution, 100-300?units/mg protein (Lowry)
Packaging: 50units
Price: $365
Updated: 2024/03/01

Sigma-Aldrich

Product number: S7651
Product name: Sphingomyelinase from Bacillus cereus
Purity: lyophilized powder, ≥100?units/mg protein
Packaging: 10units
Price: $37.32
Updated: 2024/03/01

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SPHINGOMYELINASE Chemical Properties,Usage,Production

Uses

sphingomyelinase is a fluid that can enhance the skin’s moistureretention properties.

Uses

Sphingomyelinase from Bacillus cereus has been used:

in the measurement of membrane capacitance in brain slices
for testing and confirming its silkworm-killing activity
in enzyme activity assay and for elucidating its effect on hydrolysis of sphingomyelin in complex lipid mixtures

Uses

Sphingomyelinase from Staphylococcus aureus has been used to:

induce neurotoxicity in rat cortical cultures to study the protective effects of minocycline
determine the concentration of sphingomyelin from serum samples
enhance sphingomyelinase activity to study PARK9-mediated exosome biogenesis

General Description

Sphingomyelinase from Bacillus cereus (Bc-Smase) is a Mg²⁺-containing metalloenzyme. Bacillus cereus sphingomyelinase induces hemolysis of sheep erythrocytes.

Biochem/physiol Actions

Initiates the formation of sphingomyelin-based second messengers. Activates MAPK (mitogen-activated protein kinase) and SAPKs (stress-activated protein kinases); generates ceramide from sphingomyelin.

SPHINGOMYELINASE Preparation Products And Raw materials

Raw materials

Preparation Products

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SPHINGOMYELINASE Suppliers

China 20 Germany 1 Switzerland 1 United Kingdom 1 United States 7 Global 30

Sigma-Aldrich

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Shanghai Guchen Biotechnology Co., LTD

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9031-54-3, SPHINGOMYELINASERelated Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Tris(2,4-pentanedionato)chroMiuM(III) Cupric acetylacetonate Ethyl isocyanoacetate TERT-BUTYL ISOCYANIDE N-BUTYLISOCYANIDE SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) PHENYLSELENOL Tosylmethyl isocyanide 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Benzyl isocyanide COBALT(II) ACETYLACETONATE 2,4-PENTANEDIONE, SILVER DERIVATIVE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Aluminum acetylacetonate METHYL ISOCYANOACETATE SPHINGOMYELIN

EC 3.1.4.12

SPHINGOMYELINASE

SPHINGOMYELINASE, STAPHYLOCOCCUS AUREUS

SPHINGOMYELIN CHOLINE PHOSPHOHYDROLASE

SPHINGOMYELIN PHOSPHODIESTERASE

sphingomyelinase from human placenta

Sphingomyelinase C

SPHINGOMYELINASE FROM STAPHYLOCOCCUS*AUR EUS

SPHINGOMYELINASE (SPHINGOMYELIN PHOSPHOD IESTERASE)

SPHINGOMYELINASE FROM BACILLUS CEREUS

SPHINGOMYELINASE FROM STREPTOMYCES SP.

Sphingomyelin choline phosphohydrolase, Sphingomyelin phosphodiesterase

Native Sphingomyelinase from Streptomyces sp.

Native Bacillus cereus Sphingomyelinase

Native Staphylococcus aureus Sphingomyelinase

Sphingomyelinase from Bacillus cereus lyophilized powder, >=100 units/mg protein

Sphingomyelinase from Bacillus cereus buffered aqueous glycerol solution, >=100 units/mg protein (Lowry)

9031-54-3

Lipid Metabolism

Metabolomics

General Metabolic Enzymes

Biochemicals and Reagents

Application Index

BioChemical

Cell Dissociation

Cell Dissociation and Cell Lysis

Enzymes, Inhibitors, and Substrates