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SPHINGOMYELINASE

Product Name
SPHINGOMYELINASE
CAS No.
9031-54-3
Chemical Name
SPHINGOMYELINASE
Synonyms
EC 3.1.4.12;SPHINGOMYELINASE;Sphingomyelinase C;SPHINGOMYELIN PHOSPHODIESTERASE;sphingomyelinase from human placenta;SPHINGOMYELINASE FROM BACILLUS CEREUS;SPHINGOMYELINASE FROM STREPTOMYCES SP.;SPHINGOMYELIN CHOLINE PHOSPHOHYDROLASE;SPHINGOMYELINASE, STAPHYLOCOCCUS AUREUS;Native Bacillus cereus Sphingomyelinase
CBNumber
CB4393078
Formula Weight
0
MOL File
Mol file
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SPHINGOMYELINASE Property

storage temp. 
2-8°C
form 
lyophilized powder
color 
White to off-white
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Safety

Hazard Codes 
B
Safety Statements 
23-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S9396
Product name
Sphingomyelinase from Bacillus cereus
Purity
buffered aqueous glycerol solution, ≥100?units/mg protein (Lowry)
Packaging
25units
Price
$227
Updated
2024/03/01
Sigma-Aldrich
Product number
S9396
Product name
Sphingomyelinase from Bacillus cereus
Purity
buffered aqueous glycerol solution, ≥100?units/mg protein (Lowry)
Packaging
50units
Price
$383
Updated
2024/03/01
Sigma-Aldrich
Product number
S8633
Product name
Sphingomyelinase from Staphylococcus aureus
Purity
buffered aqueous glycerol solution, 100-300?units/mg protein (Lowry)
Packaging
25units
Price
$215
Updated
2024/03/01
Sigma-Aldrich
Product number
S8633
Product name
Sphingomyelinase from Staphylococcus aureus
Purity
buffered aqueous glycerol solution, 100-300?units/mg protein (Lowry)
Packaging
50units
Price
$365
Updated
2024/03/01
Sigma-Aldrich
Product number
S7651
Product name
Sphingomyelinase from Bacillus cereus
Purity
lyophilized powder, ≥100?units/mg protein
Packaging
10units
Price
$37.32
Updated
2024/03/01
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SPHINGOMYELINASE Chemical Properties,Usage,Production

Uses

sphingomyelinase is a fluid that can enhance the skin’s moistureretention properties.

Uses

Sphingomyelinase from Bacillus cereus has been used:

  • in the measurement of membrane capacitance in brain slices
  • for testing and confirming its silkworm-killing activity
  • in enzyme activity assay and for elucidating its effect on hydrolysis of sphingomyelin in complex lipid mixtures

Uses

Sphingomyelinase from Staphylococcus aureus has been used to:

  • induce neurotoxicity in rat cortical cultures to study the protective effects of minocycline
  • determine the concentration of sphingomyelin from serum samples
  • enhance sphingomyelinase activity to study PARK9-mediated exosome biogenesis

General Description

Sphingomyelinase from Bacillus cereus (Bc-Smase) is a Mg2+-containing metalloenzyme. Bacillus cereus sphingomyelinase induces hemolysis of sheep erythrocytes.

Biochem/physiol Actions

Initiates the formation of sphingomyelin-based second messengers. Activates MAPK (mitogen-activated protein kinase) and SAPKs (stress-activated protein kinases); generates ceramide from sphingomyelin.

SPHINGOMYELINASE Preparation Products And Raw materials

Raw materials

Preparation Products

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SPHINGOMYELINASE Suppliers

China 20 Germany 1 Switzerland 1 United Kingdom 1 United States 7 Global 30
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9031-54-3, SPHINGOMYELINASERelated Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Tris(2,4-pentanedionato)chroMiuM(III) Cupric acetylacetonate Ethyl isocyanoacetate TERT-BUTYL ISOCYANIDE N-BUTYLISOCYANIDE SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) PHENYLSELENOL Tosylmethyl isocyanide 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Benzyl isocyanide COBALT(II) ACETYLACETONATE 2,4-PENTANEDIONE, SILVER DERIVATIVE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Aluminum acetylacetonate METHYL ISOCYANOACETATE SPHINGOMYELIN

  • EC 3.1.4.12
  • SPHINGOMYELINASE
  • SPHINGOMYELINASE, STAPHYLOCOCCUS AUREUS
  • SPHINGOMYELIN CHOLINE PHOSPHOHYDROLASE
  • SPHINGOMYELIN PHOSPHODIESTERASE
  • sphingomyelinase from human placenta
  • Sphingomyelinase C
  • SPHINGOMYELINASE FROM STAPHYLOCOCCUS*AUR EUS
  • SPHINGOMYELINASE (SPHINGOMYELIN PHOSPHOD IESTERASE)
  • SPHINGOMYELINASE FROM BACILLUS CEREUS
  • SPHINGOMYELINASE FROM STREPTOMYCES SP.
  • Sphingomyelin choline phosphohydrolase, Sphingomyelin phosphodiesterase
  • Native Sphingomyelinase from Streptomyces sp.
  • Native Bacillus cereus Sphingomyelinase
  • Native Staphylococcus aureus Sphingomyelinase
  • Sphingomyelinase from Bacillus cereus lyophilized powder, >=100 units/mg protein
  • Sphingomyelinase from Bacillus cereus buffered aqueous glycerol solution, >=100 units/mg protein (Lowry)
  • 9031-54-3
  • Lipid Metabolism
  • Metabolomics
  • General Metabolic Enzymes
  • Biochemicals and Reagents
  • Application Index
  • BioChemical
  • Cell Dissociation
  • Cell Dissociation and Cell Lysis
  • Enzymes, Inhibitors, and Substrates