YANGONIN
Uses- Product Name
- YANGONIN
- CAS No.
- 500-62-9
- Chemical Name
- YANGONIN
- Synonyms
- Yan;Y100550;YANGONIN;Yangonin-RM;11-METHOXYYANGONIN;Yangoninpproved, it should be;4-methoxy-6-(p-methoxystyryl)-2h-pyran-2-on;Yangonin, 98%, from Piper methysticum Forst;4-methoxy-6-(p-methoxystyryl)-2h-pyran-2-one;4-Methoxy-6-((E)-4-methoxystyryl)pyran-2-one
- CBNumber
- CB4393593
- Molecular Formula
- C15H14O4
- Formula Weight
- 258.27
- MOL File
- 500-62-9.mol
YANGONIN Property
- Melting point:
- 155-157°
- Boiling point:
- 487.6±45.0 °C(Predicted)
- Density
- 1.325 g/cm3
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Pale Yellow to Pale Green
- BRN
- 230710
- Stability:
- Light Sensitive
- LogP
- 1.750 (est)
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 75575
- Product name
- Yangonin
- Purity
- analytical standard
- Packaging
- 5MG
- Price
- $501
- Updated
- 2022/05/15
- Product number
- 14351
- Product name
- Yangonin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 14351
- Product name
- Yangonin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $180
- Updated
- 2024/03/01
- Product number
- 14351
- Product name
- Yangonin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $270
- Updated
- 2024/03/01
- Product number
- 14351
- Product name
- Yangonin
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $595
- Updated
- 2024/03/01
YANGONIN Chemical Properties,Usage,Production
Uses
A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
Description
Yangonin is a natural kavalactone from the kava plant, P. methysticum. It enhances the binding of bicuculline at the γ-amino butyric acid (GABA) receptor GABAA at 1.0 μM. Yangonin also binds the central cannabinoid (CB1) receptor with a Ki value of 0.72 μM, but whether it serves as an agonist or antagonist at this receptor remains to be determined. Yangonin blocks the activation of NF-κB by TNF-α. It also inhibits anchorage-dependent and independent growth of bladder cancer cell lines through induction of autophagic cell death (IC50s = 15-59 mg/mL).
Uses
A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
Uses
A lactone isolated from the Kava plant (Piper methysticum). rokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety d isorders. a supplements.
Definition
ChEBI: Yangonin is a member of 2-pyranones and an aromatic ether.
YANGONIN Preparation Products And Raw materials
Raw materials
Preparation Products
YANGONIN Suppliers
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View Lastest Price from YANGONIN manufacturers
- Product
- Yangonin 500-62-9
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-02-25
- Product
- YANGONIN 500-62-9
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-25