RUSCOGENIN

Product Name: RUSCOGENIN
CAS No.: 472-11-7
Chemical Name: RUSCOGENIN
Synonyms: RUSCOGENINE;HeModren;FlebopoM;Ruscogeni;RUSCOGENIN;Rectolander;Ruscorectal;RUSCOGENIN(P);Ruscogenins CRS;RUSCOGENIN USP/EP/BP
CBNumber: CB4411307
Molecular Formula: C27H42O4
Formula Weight: 430.63
MOL File: 472-11-7.mol

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RUSCOGENIN Property

Melting point:: 198-202℃
Boiling point:: 563.1±50.0 °C(Predicted)
Density: 1.18
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka: 14.56±0.70(Predicted)
form: Solid
color: White
InChIKey: QMQIQBOGXYYATH-ORLFXEBYNA-N

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Safety

Safety Statements: 24/25
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00295
Product name: Ruscogenin
Purity: ≥98% (HPLC)
Packaging: 5 mg
Price: $330
Updated: 2025/07/31

Cayman Chemical

Product number: 25217
Product name: Ruscogenin
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 25217
Product name: Ruscogenin
Purity: ≥98%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 25217
Product name: Ruscogenin
Purity: ≥98%
Packaging: 10mg
Price: $243
Updated: 2024/03/01

Cayman Chemical

Product number: 25217
Product name: Ruscogenin
Purity: ≥98%
Packaging: 25mg
Price: $533
Updated: 2024/03/01

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RUSCOGENIN Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner.

Definition

ChEBI: Ruscogenin is a triterpenoid.

Biological Activity

Ruscogenin is a well-known compound for down-regulating nuclear factor kappa B (NF-KB), intercellular adhesion molecule-1 (ICAM-1), tissue factor (TF), inducible NO synthase (iNOS), and modulating inflammatory pathways. It displays anti-inflammatory properties by inhibiting lipopolysaccharide (LPS)-induced acute lung injury (ALI), and improving diabetic nephropathy in in vivo studies. Ruscogenin also exerts neuroprotective properties and protects the brain against ischemic injury in mouse model. It elicits anti-tumor properties by inducing ferroptosis in pancreatic cancer cells in both in vitro and in vivo studies.

target

PGE | TNF-α | NF-kB | p65 | NO | NOS | COX | ERK | JNK | Akt | p38MAPK | PKA | cAMP | IL Receptor

RUSCOGENIN Preparation Products And Raw materials

Raw materials

Preparation Products

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RUSCOGENIN Suppliers

Canada 1 China 223 Germany 2 India 4 United Kingdom 3 United States 14 USA 1 Global 248

ALB Technology Limited

Tel: 702-983-3769
Fax: 702-983-3769
Email: sales@albtechnology.com
Country: United States
ProdList: 2993
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

ApexBio Technology

Tel: --
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Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

3B Scientific Corporation

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Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

Cayman Chemical Company

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Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

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Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

MedChemExpress

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Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

FortopChem Technology Limited

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Email: sales@fortopchem.com
Country: United States
ProdList: 1099
Advantage: 50

ChromaDex

Tel: --
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Email: sales@chromadex.com
Country: United States
ProdList: 2501
Advantage: 76

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View Lastest Price from RUSCOGENIN manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: RUSCOGENIN 472-11-7
Price: US $1.00-45.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 2000KG
Release date: 2024-08-01

Shanghai Standard Technology Co., Ltd.

Product: Ruscogenin 472-11-7
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-31

Career Henan Chemical Co

Product: RUSCOGENIN 472-11-7
Price: US $1.00/kg
Min. Order: 1g
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-25

472-11-7, RUSCOGENINRelated Search:

Centella asiatica extract 3-(1,3-Benzodioxol-5-ylmethyl)-3,4-dihydro-5,7-dihydroxy-8-methyl-4-oxo-2H-1-benzopyran-6-carboxaldehyde Ophiopogonanone B Ophiopogonis Extract Diosgenin FORSYTHIN lithospermic acid B AURANTIO-OBTUSIN SENEGENIN Ophiopogonin A RUSCOGENIN NEORUSCOGENIN ophiopogonin B S-Ruscogenin,(25S)-Ruscogenin OPHIOPOGONIN D OPHIOPOGONIN C ruscogenin-1-yl xylopyranosyl-1-3-(glucopyranosyl-1-2)fucopyranoside RUSCOGENIN(PRIMARY STANDARD)

FlebopoM

HeModren

Rectolander

Ruscogenin, froM Ophiopogon japonicus

(1B,3B,25R)-SPIROST-5-ENE-1,3-DIOL

RUSCOGENIN

RUSCOGENINE

(25R)-spirost-5-ene-1-beta,3-beta-diol

Spirost-5-ene-1,3-diol, (1.beta.,3.beta.,25R)-

RUSCOGENIN(P)

(1beta,3beta,25R)-Spirost-5-ene-1,3-diol

(1β,3β,25R)-Spirost-5-ene-1,3-diol

25D-Spirost-5-ene-1β,3β-diol

Ruscogenin, 98%, from Ophiopogon japonicus (Thunb.) Ker Gawl.

(25R)-Spirost-5-ene-1β,3β-diol

Ruscorectal

Ruscogenins CRS

Spirost-5-ene-1,3-diol, (1β,3β,25R)-

RUSCOGENIN USP/EP/BP

Ruscogeni

Ruscogenin (6CI, 7CI)

Ruscogenin, 10 mM in DMSO

(1β,3β,25R)-Spirost-5-ene-1,3-diol

(4R,5'R,6R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-Tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4,6-diol

472-11-7

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