ChemicalBook > CAS DataBase List > TYRPHOSTIN A1

TYRPHOSTIN A1

Product Name
TYRPHOSTIN A1
CAS No.
2826-26-8
Chemical Name
TYRPHOSTIN A1
Synonyms
AG 9;TYRPHOSTINA;TYRPHOSTIN 1;TYRPHOSTIN A1;TYRPHOSTIN AG 9;AKOS USSH-4110227;TYRPHOSTIN A1 99+%;RARECHEM AL BX 0083;Tyrphostin A1, 10 mM in DMSO;4-METHOXYBENZLIDENEMALONONITRILE
CBNumber
CB4415002
Molecular Formula
C11H8N2O
Formula Weight
184.19
MOL File
2826-26-8.mol
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TYRPHOSTIN A1 Property

Melting point:
113-116 °C(lit.)
Boiling point:
352.4±27.0 °C(Predicted)
Density 
1.169±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
chloroform: soluble50mg/mL, clear, light yellow
form 
Yellow solid
color 
Light orange to Yellow to Green
λmax
350nm(H2O)(lit.)
Sensitive 
Light Sensitive
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36/37
RIDADR 
UN 3439 6.1/PG III
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T7040
Product name
Tyrphostin 1
Purity
≥98%
Packaging
25mg
Price
$196
Updated
2025/07/31
TCI Chemical
Product number
T3074
Product name
Tyrphostin A1
Purity
>98.0%(GC)
Packaging
200mg
Price
$178
Updated
2025/07/31
TCI Chemical
Product number
T3074
Product name
Tyrphostin A1
Purity
>98.0%(GC)
Packaging
1g
Price
$535
Updated
2025/07/31
TRC
Product number
T947963
Product name
Tyrphostin A1
Packaging
50mg
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-3182
Product name
Tyrphostin A1
Purity
99.50%
Packaging
100mg
Price
$242
Updated
2021/12/16
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TYRPHOSTIN A1 Chemical Properties,Usage,Production

Chemical Properties

light yellow crystalline needles or crystals

Uses

Tyrphostin A1 is an inactive Tyrphostin used as a negative control for Tyrphostin A23.

Definition

ChEBI: Tyrphostin 1 is a member of methoxybenzenes. It has a role as a geroprotector.

Synthesis Reference(s)

Synthetic Communications, 21, p. 1163, 1991 DOI: 10.1080/00397919108021035
Synthesis, p. 23, 1970

Biological Activity

Tyrphostin 1 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain. Tyrphostin 1 is also known to block EGF-dependent receptor autophosphorylation,. Furthermore, studies have reported th at tyrphostin 1 can block Ca2+ channels and inhibit growth in vascular smooth muscle cells,.', 'EGFR tyrosine kinase inhibitor.

TYRPHOSTIN A1 Preparation Products And Raw materials

Raw materials

Preparation Products

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TYRPHOSTIN A1 Suppliers

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