APETx2

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Product Name: APETx2
CAS No.: 713544-47-9
Chemical Name: APETx2
Synonyms: APETx2;Cys6-Cys30;Cys20-Cys38);APETx2 USP/EP/BP;H-Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp-OH(Disulfide bridge：Cys4-Cys37;2-[2-[[1-[2-[[52-[2-[[2-[(2-aminoacetyl)amino]-3-hydroxybutanoyl]amino]propanoylamino]-34-(4-aminobutyl)-40-(2-amino-2-oxoethyl)-19,69-dibenzyl-28-butan-2-yl-13,75,96-tris(3-carbamimidamidopropyl)-99-(carboxymethyl)-2~{a},60,87-tris(1-hydroxyethyl)-4,37,49,81-tetrakis(hydroxymethyl)-16,25,72,90-tetrakis[(4-hydroxyphenyl)methyl]-22-(1~{H}-indol-3-ylmethyl)-66-(2-methylpropyl)-1~{a},3,4~{a},6,10~{a},12,15,17~{a},18,21,24,27,30,33,36,39,42,45,48,51,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tetratriacontaoxo-12~{a},13~{a},19~{a},20~{a},54,55-hexathia-~{a},2,3~{a},5,9~{a},11,14,16~{a},17,20,23,26,2
CBNumber: CB44673963
Molecular Formula: C196H280N54O61S6
Formula Weight: 0
MOL File: Mol file

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APETx2 Property

storage temp.: Store at -20°C
form: Powder
Water Solubility: Soluble to 5 mg/ml in water

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 4804
Product name: APETx2
Packaging: 100U
Price: $363
Updated: 2021/12/16

Usbiological

Product number: 254652
Product name: APETx2
Packaging: 100ug
Price: $644
Updated: 2021/12/16

ApexBio Technology

Product number: B5720
Product name: APETx2
Packaging: 100ug
Price: $528
Updated: 2021/12/16

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APETx2 Chemical Properties,Usage,Production

Uses

APETx2 is a highly pure, synthetic and biologically active peptide toxin.

Biological Activity

APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible acid-sensing ion channel inhibitor of ASIC3 (acid-sensing ion channel) with IC50 of 63 nM. It acts outside the ASIC3 channel. APETx2 reverses acid-induced inflammatory pain.

in vitro

APETx2 (it or im application, 0.022 to 2.2 μM) resulted in a potent and complete reversal of established mechanical hypersensitivity in the complete Freund's adjuvant (CFA) inflammatory pain model.

storage

Store at -20°C

APETx2 Preparation Products And Raw materials

Raw materials

Preparation Products

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APETx2 Suppliers

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713544-47-9, APETx2Related Search:

TCS 184 D-Trp(34) neuropeptide Y AC-LEU-ASP-GLN-TRP-PHE-GLY-NH2 PTH (1-84) (HUMAN) Compstatin control peptide ECHISTATIN GATX2 ω-Agatoxin TK Cyclo[L-α-aspartyl-D-phenylalanyl-L-lysyl-N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-L-ornithylglycyl], 1,1-dimethylethyl ester MM 54 (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) Vosoritide acetate PDZ1 DOMAIN INHIBITOR PEPTIDE

APETx2

2-[2-[[1-[2-[[52-[2-[[2-[(2-aminoacetyl)amino]-3-hydroxybutanoyl]amino]propanoylamino]-34-(4-aminobutyl)-40-(2-amino-2-oxoethyl)-19,69-dibenzyl-28-butan-2-yl-13,75,96-tris(3-carbamimidamidopropyl)-99-(carboxymethyl)-2~{a},60,87-tris(1-hydroxyethyl)-4,37,49,81-tetrakis(hydroxymethyl)-16,25,72,90-tetrakis[(4-hydroxyphenyl)methyl]-22-(1~{H}-indol-3-ylmethyl)-66-(2-methylpropyl)-1~{a},3,4~{a},6,10~{a},12,15,17~{a},18,21,24,27,30,33,36,39,42,45,48,51,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tetratriacontaoxo-12~{a},13~{a},19~{a},20~{a},54,55-hexathia-~{a},2,3~{a},5,9~{a},11,14,16~{a},17,20,23,26,2

APETx2 USP/EP/BP

Cys20-Cys38)

Cys6-Cys30

H-Gly-Thr-Ala-Cys-Ser-Cys-Gly-Asn-Ser-Lys-Gly-Ile-Tyr-Trp-Phe-Tyr-Arg-Pro-Ser-Cys-Pro-Thr-Asp-Arg-Gly-Tyr-Thr-Gly-Ser-Cys-Arg-Tyr-Phe-Leu-Gly-Thr-Cys-Cys-Thr-Pro-Ala-Asp-OH(Disulfide bridge：Cys4-Cys37

713544-47-9

C196H280N54O61S6