4-THIOURACIL

ChemicalBook > CAS DataBase List > 4-THIOURACIL

Product Name: 4-THIOURACIL
CAS No.: 591-28-6
Chemical Name: 4-THIOURACIL
Synonyms: KC 135;4-thiouracyl;4-THIOURACIL;4-Thiouracil97%;Uracil, 4-thio-;4-Thiouracil 97%;4-Thiouracil ,98%;4-mercaptopyrimidin-2-ol;4-Thioxo-1H-pyrimidin-2-one;2-HYDROXY-4-MERCAPTOPYRIMIDINE
CBNumber: CB4469328
Molecular Formula: C4H4N2OS
Formula Weight: 128.15
MOL File: 591-28-6.mol

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4-THIOURACIL Property

Melting point:: 295 °C (dec.) (lit.)
Density: 1.368 (estimate)
refractive index: 1.7000 (estimate)
storage temp.: Store at -20°C
solubility: 1 M NaOH: soluble50mg/mL
form: Powder
pka: 5.38±0.20(Predicted)
color: Yellow
CAS DataBase Reference: 591-28-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36
WGK Germany: 3
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 440736
Product name: 4-Thiouracil
Purity: 97%
Packaging: 1g
Price: $105
Updated: 2024/03/01

TCI Chemical

Product number: T2757
Product name: 4-Thiouracil
Purity: >97.0%(HPLC)(T)
Packaging: 1g
Price: $137
Updated: 2024/03/01

Alfa Aesar

Product number: H61919
Product name: 4-Thiouracil, 97%
Packaging: 1g
Price: $80.65
Updated: 2024/03/01

Alfa Aesar

Product number: H61919
Product name: 4-Thiouracil, 97%
Packaging: 250mg
Price: $29.1
Updated: 2023/06/20

Cayman Chemical

Product number: 16952
Product name: 4-Thiouracil
Purity: ≥98%
Packaging: 1g
Price: $88
Updated: 2024/03/01

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4-THIOURACIL Chemical Properties,Usage,Production

Description

4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts. It absorbs ultraviolet light >300 nm and, in the presence of oxygen, acts as an energy donor to produce singlet oxygen by triplet-triplet energy transfer. The highly reactive oxygen species then reacts readily with 4-thiouracil, leading to the production of uracil and uracil-6-sulfonate, which is fluorescent at a wavelength of ~390 nm. 4-Thiouracil is used as a T. gondii uracil phosphoribosyltransferase substrate to produce 4-thiouridine monophosphate, which can ultimately be incorporated into RNA.

Chemical Properties

yellow powder

Uses

4-Thiouracil is suitable reagent employed in Schneider′s media for the embryos during RNA extraction. It may be employed as reagent for the Northwestern blotting technique.

Uses

4-Thiouracil is a derivative of Uracil (U801000), which is a nitrogenous base in RNA nucleic acid. 4-Thiouracil is used for tagging in cell type-specific RNA isolation from intact complex tissues.

Synthesis Reference(s)

Synthesis, p. 256, 1987 DOI: 10.1055/s-1987-27906

4-THIOURACIL Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Ethanol Phosphorus oxychloride 2-Thiouracil Benzene Hydrochloric acid Ethylene glycol Acetic acid Sodium hydroxide Sodium hydrosulfide Magnesium sulfate Iodomethane Carbon

Preparation Products

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View Lastest Price from 4-THIOURACIL manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Thiouracil 591-28-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-14

Career Henan Chemical Co

Product: 4-THIOURACIL 591-28-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-24

591-28-6, 4-THIOURACILRelated Search:

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4-Thiouracil97%

4-Thiouracil 97%

2(1H)-Pyrimidinone, 3,4-dihydro-4-thioxo- (9CI)

4-Thiouracil ,98%

4-Thioxo-1H-pyrimidin-2-one

2-HYDROXY-4-MERCAPTOPYRIMIDINE / 4-THIOURACIL

4-thiouracyl

4-sulfanylidene-1,2,3,4-tetrahydropyriMidin-2-one

2-Hydroxy-4-mercaptopyrimidine 3,4-Dihydro-4-thioxo-2(1H)-pyrimidinone

4-thioxo-3,4-dihydropyriMidin-2(1H)-one

4-mercaptopyrimidin-2-ol

2(1H)-Pyrimidinone, 3,4-dihydro-4-thioxo-

KC 135

Uracil, 4-thio-

4-THIOURACIL

2-HYDROXY-4-MERCAPTOPYRIMIDINE

3,4-Dihydro-4-thioxo-2(1H)-pyrimidinone

4-sulfanylidene-1H-pyrimidin-2-one

2-hydroxypyrimidine-4(3H)-thione

591-28-6

C4H4N2OS

Building Blocks

Heterocyclic Building Blocks

Pyrimidines

PYRIMIDINE