4-Iodo-2-(trifluoromethyl)pyridine

Product Name: 4-Iodo-2-(trifluoromethyl)pyridine
CAS No.: 590371-73-6
Chemical Name: 4-Iodo-2-(trifluoromethyl)pyridine
Synonyms: 4-lodo-2-(trifluoromethyl)pyridine;4-IODO-2-(TRIFLUOROMETHYL)PYRIDINE;4-IODE-2-(TRIFLUOROMETHYL)PYRIDINE;2-(trifluoroMethyl)-4-iodopyridine;Pyridine,4-iodo-2-(trifluoromethyl)-;4-Iodo-2-(trifluoromethyl)pyridine97%;4-Iodo-2-(trifluoromethyl)pyridine 97%;4-Iodo-2-(trifluoromethyl)pyridine ISO 9001：2015 REACH;4-Iode-2-(trifluoromethyl)pyridine (not restricted/prohibited)(lab chemical)
CBNumber: CB4722177
Molecular Formula: C6H3F3IN
Formula Weight: 272.99
MOL File: 590371-73-6.mol

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4-Iodo-2-(trifluoromethyl)pyridine Property

Melting point:: 24-26 °C
Boiling point:: 206.2±35.0 °C(Predicted)
Density: 1.974g/ml
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: liquid
pka: -0.82±0.20(Predicted)
color: Clear, colourless to pale yellow

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: I724775
Product name: 4-Iodo-2-(trifluoromethyl)pyridine
Packaging: 5G
Price: $295
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-K-42
Product name: 4-Iodo-2-(trifluoromethyl)pyridine
Purity: 95%
Packaging: 5G
Price: $341
Updated: 2021/12/16

Apolloscientific

Product number: PC8981
Product name: 4-Iodo-2-(trifluoromethyl)pyridine
Purity: 95%
Packaging: 5g
Price: $213
Updated: 2021/12/16

Apolloscientific

Product number: PC8981
Product name: 4-Iodo-2-(trifluoromethyl)pyridine
Purity: 95%
Packaging: 250mg
Price: $20
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-K-42
Product name: 4-Iodo-2-(trifluoromethyl)pyridine
Purity: 95%
Packaging: 250mg
Price: $32
Updated: 2021/12/16

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4-Iodo-2-(trifluoromethyl)pyridine Chemical Properties,Usage,Production

Uses

4-Iodo-2-(trifluoromethyl)pyridine is used as a reagent in the synthesis of aminoisoindoles as β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors which exhibit in vivo brain reduction of β-amyloid peptides.

Reactivity Profile

4-Iodo-2-(trifluoromethyl)pyridine could be cleanly deprotonated by LIDA in tetrahydrofuran at –75 °C[1]. Trapping of the organometallic intermediates with dry ice followed by neutralization gave the 4-iodo-2-(trifluoromethyl)pyridine-3-carboxylic acid (16, 31%). a: LIDA in THF at –75 °C for 2 h; b: (1.) Excess solid carbon dioxide, (2.) Hydrochloric acid.

References

[1] Schlosser M, et al. Further Metalations and Functionalizations of Chloro-, Bromo- and Iodo(trifluoromethyl)pyridines. Synthesis, 2004; 10: 1619-1624.

4-Iodo-2-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Iodo-2-(trifluoromethyl)pyridine Suppliers

China 84 Germany 3 India 2 United Kingdom 2 United States 12 Global 103

J & K SCIENTIFIC LTD.

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Aemon Chemical

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View Lastest Price from 4-Iodo-2-(trifluoromethyl)pyridine manufacturers

Dideu Industries Group Limited

Product: 4-Iodo-2-(trifluoromethyl)pyridine 590371-73-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-27

Career Henan Chemical Co

Product: 4-Iodo-2-(trifluoromethyl)pyridine 590371-73-6
Price: US $6.00/KG
Min. Order: 1KG
Purity: 95%-98%
Supply Ability: 100
Release date: 2019-09-04

590371-73-6, 4-Iodo-2-(trifluoromethyl)pyridine Related Search:

2,4,6-Collidine (Trifluoromethyl)trimethylsilane 2-(Trifluoromethyl)pyridine 4-Methylpyridine 2-Chloro-5-chloromethylpyridine 3-(Trifluoromethyl)benzaldehyde Azamethiphos Trimethylsulfoxonium iodide Trifluoromethanesulfonic anhydride 4-(Trifluoromethyl)pyridine 3-（trifluoromethyl) Cinnamaldehyde Pyridine 3-Trifluoromethylpyridine 4-Iodo-2-methylpyridine 2-Iodo-5-trifluoromethylpyridine 2-CHLORO-4-IODO-6-(TRIFLUOROMETHYL)PYRIDINE Trifluoromethyl 3-Chloro-2-iodo-5-(trifluoromethyl)pyridine

4-Iodo-2-(trifluoromethyl)pyridine97%

4-Iodo-2-(trifluoromethyl)pyridine 97%

4-IODO-2-(TRIFLUOROMETHYL)PYRIDINE

Pyridine,4-iodo-2-(trifluoromethyl)-

2-(trifluoroMethyl)-4-iodopyridine

4-IODE-2-(TRIFLUOROMETHYL)PYRIDINE

4-Iodo-2-(trifluoromethyl)pyridine ISO 9001：2015 REACH

4-Iode-2-(trifluoromethyl)pyridine (not restricted/prohibited)(lab chemical)

4-lodo-2-(trifluoromethyl)pyridine

590371-73-6

1250277-69-2

Pyridine

Pyridine series

Halides

Pyridines

Heterocycle

Fluorine series