ESTRONE 3-O-SULFAMATE

Product Name: ESTRONE 3-O-SULFAMATE
CAS No.: 148672-09-7
Chemical Name: ESTRONE 3-O-SULFAMATE
Synonyms: EMATE;ESTRONE SULFAMATE;ESTRONE O-SULFAMATE;ESTRONE 3-SULFAMATE;ESTRONE 3-O-SULFAMATE;1,3,5(10)-Estratrien-17-one 3-sulfamate;Estrone sulfamate (Estrone 3-O-Sulfamate;1,3,5[10]-ESTRATRIEN-3-OL-17-ONE SULFAMATE;3-HYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE 3-SULFAMATE;3-[(AMinosulfonyl)oxy]estra-1,3,5(10)-trien-17-one
CBNumber: CB4739432
Molecular Formula: C18H23NO4S
Formula Weight: 349.44
MOL File: 148672-09-7.mol

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ESTRONE 3-O-SULFAMATE Property

Melting point:: 195-197°C
Boiling point:: 530.9±60.0 °C(Predicted)
Density: 1.314±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO, Ethanol, Methanol
form: Solid
pka: 8.86±0.70(Predicted)
color: Pale Beige
Stability:: Hygroscopic

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: E889060
Product name: Estrone3-O-Sulfamate
Packaging: 1mg
Price: $110
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 9910
Product name: Estrone3-O-Sulfamate
Packaging: 1mg
Price: $290
Updated: 2021/12/16

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ESTRONE 3-O-SULFAMATE Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Crystalline Solid

Uses

A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM.

Purification Methods

Estrone 3-O-sulfamate [148672-09-7] M 349.5. Estrone 3-O-sulfamate is purified by silica gel flash chromatography to give a product with one spot on TLC. It is an active site-directed inhibitor of estrone sulfatase, i.e. a time-dependent enzyme inactivator. [Woo et al. J Med Chem 39 1349 1996, Purohit et al. Biochemistry 34 11508 1995.]

ESTRONE 3-O-SULFAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ESTRONE 3-O-SULFAMATE Suppliers

Canada 1 China 19 Germany 1 India 3 Switzerland 1 United Kingdom 1 United States 4 Global 30

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148672-09-7, ESTRONE 3-O-SULFAMATERelated Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Tosylmethyl isocyanide Aluminum acetylacetonate SALCOMINE N-BUTYLISOCYANIDE Cupric acetylacetonate Ferric acetylacetonate TERT-BUTYL ISOCYANIDE 2,4-PENTANEDIONE, SILVER DERIVATIVE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) METHYL ISOCYANOACETATE Ethyl isocyanoacetate Benzyl isocyanide COBALT(II) ACETYLACETONATE PHENYLSELENOL Estrone

ESTRONE 3-O-SULFAMATE

ESTRONE 3-SULFAMATE

ESTRONE SULFAMATE

ESTRONE O-SULFAMATE

3-HYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE 3-SULFAMATE

Estrone 3-sulfamate, Estrone O-Sulfamate, Estrone Sulfamate

1,3,5[10]-ESTRATRIEN-3-OL-17-ONE SULFAMATE

1,3,5(10)-Estratrien-17-one 3-sulfamate

3-[(AMinosulfonyl)oxy]estra-1,3,5(10)-trien-17-one

EMATE

Estrone sulfamate (Estrone 3-O-Sulfamate

Estra-1,3,5(10)-trien-17-one, 3-[(aminosulfonyl)oxy]-

148672-09-7

BioChemical

Biochemicals and Reagents

Enzyme Inhibitors

D to K

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Enzyme

Estrone sulfatase

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids & Hormones - 13C & 2H

Inhibitors

Steroids