ChemicalBook > CAS DataBase List > ESTRONE 3-O-SULFAMATE
ESTRONE 3-O-SULFAMATE
- Product Name
- ESTRONE 3-O-SULFAMATE
- CAS No.
- 148672-09-7
- Chemical Name
- ESTRONE 3-O-SULFAMATE
- Synonyms
- EMATE;ESTRONE SULFAMATE;ESTRONE O-SULFAMATE;ESTRONE 3-SULFAMATE;ESTRONE 3-O-SULFAMATE;1,3,5(10)-Estratrien-17-one 3-sulfamate;Estrone sulfamate (Estrone 3-O-Sulfamate;1,3,5[10]-ESTRATRIEN-3-OL-17-ONE SULFAMATE;3-HYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE 3-SULFAMATE;3-[(AMinosulfonyl)oxy]estra-1,3,5(10)-trien-17-one
- CBNumber
- CB4739432
- Molecular Formula
- C18H23NO4S
- Formula Weight
- 349.44
- MOL File
- 148672-09-7.mol
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ESTRONE 3-O-SULFAMATE Property
- Melting point:
- 195-197°C
- Boiling point:
- 530.9±60.0 °C(Predicted)
- Density
- 1.314±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO, Ethanol, Methanol
- form
- Solid
- pka
- 8.86±0.70(Predicted)
- color
- Pale Beige
- Stability:
- Hygroscopic
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
TRC
- Product number
- E889060
- Product name
- Estrone3-O-Sulfamate
- Packaging
- 1mg
- Price
- $110
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 9910
- Product name
- Estrone3-O-Sulfamate
- Packaging
- 1mg
- Price
- $290
- Updated
- 2021/12/16
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ESTRONE 3-O-SULFAMATE Chemical Properties,Usage,Production
Chemical Properties
White to Off-White Crystalline Solid
Uses
A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM.
Purification Methods
Estrone 3-O-sulfamate [148672-09-7] M 349.5. Estrone 3-O-sulfamate is purified by silica gel flash chromatography to give a product with one spot on TLC. It is an active site-directed inhibitor of estrone sulfatase, i.e. a time-dependent enzyme inactivator. [Woo et al. J Med Chem 39 1349 1996, Purohit et al. Biochemistry 34 11508 1995.]
ESTRONE 3-O-SULFAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
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ESTRONE 3-O-SULFAMATE Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
148672-09-7, ESTRONE 3-O-SULFAMATERelated Search:
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