ChemicalBook > CAS DataBase List > 5-BROMO-2-FLUORO-6-PICOLINE

5-BROMO-2-FLUORO-6-PICOLINE

Product Name
5-BROMO-2-FLUORO-6-PICOLINE
CAS No.
375368-83-5
Chemical Name
5-BROMO-2-FLUORO-6-PICOLINE
Synonyms
3-Bromo-6-fluoro-2-methylpyridine;5-BROMO-2-FLUORO-6-PICOLINE;5-Bromo-2-flouro-6-picoline;5-Bromo-2-fluoro-6-methylpyridine;Pyridine,3-bromo-6-fluoro-2-methyl-;5-BROMO-2-FLUORO-6-PICOLINE ISO 9001：2015 REACH
CBNumber
CB4754716
Molecular Formula
C6H5BrFN
Formula Weight
190.01
MOL File
375368-83-5.mol
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5-BROMO-2-FLUORO-6-PICOLINE Property

Boiling point:
189.5±35.0 °C(Predicted)
Density 
1.592±0.06 g/cm3(Predicted)
refractive index 
1.5270-1.5310
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
clear liquid
pka
-2.07±0.10(Predicted)
color 
Colorless to Light yellow
InChI
InChI=1S/C6H5BrFN/c1-4-5(7)2-3-6(8)9-4/h2-3H,1H3
InChIKey
GUYGQQWIKZLHTP-UHFFFAOYSA-N
SMILES
C1(C)=NC(F)=CC=C1Br
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-37/38-41
Safety Statements 
26-39
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5135
Product name
3-Bromo-6-fluoro-2-methylpyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$40
Updated
2025/07/31
TCI Chemical
Product number
B5135
Product name
3-Bromo-6-fluoro-2-methylpyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$160
Updated
2025/07/31
TRC
Product number
B692663
Product name
3-Bromo-6-fluoro-2-methylpyridine
Packaging
250mg
Price
$55
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
B10104
Product name
3-Bromo-6-fluoro-2-methylpyridine
Purity
95%
Packaging
1g
Price
$5
Updated
2021/12/16
Apolloscientific
Product number
PC7144
Product name
3-Bromo-6-fluoro-2-methylpyridine
Purity
98%
Packaging
1g
Price
$10
Updated
2021/12/16
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5-BROMO-2-FLUORO-6-PICOLINE Chemical Properties,Usage,Production

Chemical Properties

Light yellow powder

Uses

5-Bromo-2-fluoro-6-methylpyridine is a Light yellow powder, it is used as an intermediate in organic synthesis and is widely used in the fields of pesticide, medicine and materials science.

Synthesis

42753-71-9

375368-83-5

The general procedure for the synthesis of 3-bromo-2-methyl-6-fluoropyridine from 2-amino-5-bromo-6-methylpyridine was as follows: 5-bromo-2-amino-6-methylpyridine (5 g) was dissolved in pyridine hydrogen fluoride (35 mL). The reaction system was cooled to -20°C, followed by the slow addition of potassium nitrite (KNO2, 2.7 g). The reaction was continued by keeping the temperature low. Once the reaction was complete, it was slowly warmed to room temperature and stirred continuously for 4 hours. The reaction mixture was slowly poured into ice water (200 mL) and extracted with a solvent mixture of dichloromethane (50 mL) and ethyl acetate (EtOAc). The organic phases were combined, washed with 1N hydrochloric acid solution and concentrated under reduced pressure to give 5-bromo-2-fluoro-6-methylpyridine (4 g, 78% yield).

References

[1] Patent: CN108341769, 2018, A. Location in patent: Paragraph 0021-0023; 0025-0027
[2] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 22, p. 3979 - 3982

5-BROMO-2-FLUORO-6-PICOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-FLUORO-6-PICOLINE Suppliers

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View Lastest Price from 5-BROMO-2-FLUORO-6-PICOLINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
5-BROMO-2-FLUORO-6-PICOLINE 375368-83-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-29
Henan Fengda Chemical Co., Ltd
Product
3-Bromo-6-fluoro-2-methylpyridine 375368-83-5
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Dideu Industries Group Limited
Product
5-BROMO-2-FLUORO-6-PICOLINE 375368-83-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-25

375368-83-5, 5-BROMO-2-FLUORO-6-PICOLINERelated Search:

2-Fluoro-6-methylpyridine 5-BROMO-2-FLUORO-3-PICOLINE,5-BROMO-2-FLUORO-3-PICOLINE (5-BROMO-2-FLUORO-3-METHYLPYRIDINE) 3-BROMO-2-FLUORO-5-PICOLINE,3-BROMO-2-FLUORO-5-PICOLINE (3-BROMO-2-FLUORO-5-METHYLPYRIDINE) 5-Bromo-2-fluoropyridine 5-Chloro-2-fluoropyridine 2-Fluoropyridine-6-carboxylic acid 2-Fluoro-3-nitropyridine 5-Bromo-2-fluoro-4-methyl-pyridine 5-Chloro-2-fluoro-3-methylpyridine 2-CHLORO-6-FLUOROPYRIDINE 4-Bromo-2-fluoropyridine 2-Fluoro-3-methylpyridine 3-Amino-2-fluoropyridine 3-Chloro-2-fluoro-pyridine 2-Fluoro-5-methylpyridine 2-Fluoro-4-methylpyridine 3-BROMO-5-CHLORO-2-FLUOROPYRIDINE 3-Chloro-2-iodopyridine

  • 5-BROMO-2-FLUORO-6-PICOLINE
  • 5-Bromo-2-fluoro-6-methylpyridine
  • 3-Bromo-6-fluoro-2-methylpyridine
  • Pyridine,3-bromo-6-fluoro-2-methyl-
  • 5-Bromo-2-flouro-6-picoline
  • 5-BROMO-2-FLUORO-6-PICOLINE ISO 9001：2015 REACH
  • 375368-83-5
  • Fluorine series
  • Pyridine Series
  • Organohalides
  • Pyridine
  • Variety of halogenated heterocyclic series
  • Heterocycles