Ozagrel hydrochloride

Product Name: Ozagrel hydrochloride
CAS No.: 78712-43-3
Chemical Name: Ozagrel hydrochloride
Synonyms: Vega;Ozag;Domenan;OKY-046 HCl;(e)-ohydrat;OZAGREL HCL;OzagrelHcl99%;oky046hydrochloride;Ozagrel Impurity 44;oky-046hydrochloride
CBNumber: CB4765488
Molecular Formula: C13H13ClN2O2
Formula Weight: 264.71
MOL File: 78712-43-3.mol

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Ozagrel hydrochloride Property

Melting point:: 214-217°
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: H₂O: soluble
form: solid
color: white to off-white
Merck: 14,6980
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
CAS DataBase Reference: 78712-43-3(CAS DataBase Reference)

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Safety

RIDADR: 3077
WGK Germany: 2
RTECS: UD3380000
HS Code: 29332900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: O1385
Product name: Ozagrel hydrochloride hydrate
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $132
Updated: 2024/03/01

Sigma-Aldrich

Product number: O1385
Product name: Ozagrel hydrochloride hydrate
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $354
Updated: 2022/05/15

TCI Chemical

Product number: O0419
Product name: Ozagrel Hydrochloride Hydrate
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $42
Updated: 2024/03/01

TCI Chemical

Product number: O0419
Product name: Ozagrel Hydrochloride Hydrate
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $124
Updated: 2024/03/01

Tocris

Product number: 1510
Product name: Ozagrelhydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $104
Updated: 2021/12/16

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Ozagrel hydrochloride Chemical Properties,Usage,Production

Description

Ozagrel HCl (78712-43-3) is a potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM).1?Does not inhibit prostacyclin (PGI2) synthase, cyclooxygenase or PGE2?isomerase (IC50 > 1 mM).1?Inhibits platelet aggregation2?in vitro?and arachidonate-induced arterial contraction?in vivo. Ozagrel HCl protects against arachidonate-induced sudden death in the rabbit3, and alleviates liver injury induced by acetaminophen overdose in mice4.

Uses

Ozagrel Hydrochloride is a selective thromboxane A2 synthase inhibitor, which alleviates liver injury induced by acetaminophen overdose in mice.

Uses

Antithrombotic;Thromboxane synthase inhibitor

Definition

ChEBI: Ozagrel hydrochloride is an organic molecular entity.

References

1) Hiraku?et al. (1986),?Pharmacological studies on the TXA2?synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046); Jpn. J. Pharmacol.,?41?393 2) Naito?et al. (1983), Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets; Eur. J. Pharmacol.,?91?41 3) Edmonds and Leffer (1984),?Protective actions of a new thromboxane synthetase inhibitor in arachidonate induced sudden death; Life Sci.,?35?1763 4) Tomishima?et al. (2013),?Ozagrel hydrochloride, a selective thromboxane A2?synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice; BMC Gastroenterol.,?30?13

Ozagrel hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ozagrel hydrochloride manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Ozagrel hydrochloride 78712-43-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: Ozagrel hydrochloride 78712-43-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Customized
Release date: 2018-12-19

78712-43-3, Ozagrel hydrochlorideRelated Search:

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OKY-046, (E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrate hydrochloride

Ozagrel hydrate hydrochloride

Domenan

OKY-046 HCl

Vega

Ozagrel hydrochloride hydrate,(E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate, OKY-046

(2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid,hydrochloride (1:1)

(E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate

Hydrochloride Ozagrel

(E)-3-(4-((1H-Imidazol-1-yl)methyl)phenyl)acrylic acid hydrochloride

Ozagrel hydrochloride hydrate, 99%, a selective thromboxane A(2) synthetase inhibitor

(E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propenoic acid hydrochloride

Ozag

(e)-3-(4-(1h-imidazol-1-ylmethyl)phenyl)-2-propenoicacidhydrochloridehydra

(e)-ohydrat

2-propenoicacid,3-(4-(1h-imidazol-1-ylmethyl)phenyl)-,monohydrochloride,mon

oky046hydrochloride

oky-046hydrochloride

OZAGREL HYDROCHLORIDE HYDRATE

OzagrelHcl99%

OzagrelHclC13H12N2O2.Hcl

(e)-3-[4-(imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride

(e)-3-(4-(1h-imidazol-1-ylmethyl)phenyl)-2-propenoic acid hydrochloride

OZAGREL HCL

OZAGREL HYDROCHLORIDE

(2E)-3-[4-(1H-IMIDAZOL-1-YLMETHYL)PHENYL]-2-PROPENOIC ACID HYDROCHLORIDE

OzagrelHydrochlorideHydrate&gt

Ozagrel Impurity 44

(E)-Ozagrel hydrochloride

trans-4-[(1-Imidazolyl)methyl]cinnamic Acid Hydrochloride

Ozagrel hydrochloride USP/EP/BP

Ozagrel HCl (OKY046 HCl

78712-43-3

C13H12N2O2ClH

C13H12N2O2HCl

C13H12N2O2HClxH2O

C13H12N2O2ClHH2O

R to Z

Thromboxane A2 synthase

Enzyme Inhibitors by Enzyme

Enzyme Inhibitors

Biochemicals and Reagents

BioChemical

Enzymes, Inhibitors, and Substrates

Inhibitors

Piperidones ,Piperidines ,Homopiperidines

Cardiovascular