ChemicalBook > CAS DataBase List > DBCO-C-PEG1

DBCO-C-PEG1

Product Name
DBCO-C-PEG1
CAS No.
2377004-09-4
Chemical Name
DBCO-C-PEG1
Synonyms
DBCO-C-PEG1;DBCO-C3-alcohol
CBNumber
CB48054692
Molecular Formula
C22H22N2O3
Formula Weight
362.42
MOL File
2377004-09-4.mol
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DBCO-C-PEG1 Property

Boiling point:
726.2±60.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO, DCM, DMF
pka
14.90±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-24379
Product name
DBCO-C3-alcohol
Purity
98%
Packaging
50mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-24379
Product name
DBCO-C3-alcohol
Purity
98%
Packaging
100mg
Price
$460
Updated
2021/12/16
BroadPharm
Product number
BP-24379
Product name
DBCO-C3-alcohol
Purity
98%
Packaging
250mg
Price
$890
Updated
2021/12/16
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DBCO-C-PEG1 Chemical Properties,Usage,Production

Description

DBCO-C3-alcohol is a linker containing a DBCO moiety and a terminal primary hydroxyl group. DBCO group can react with azides in copper-free Click Chemistry reactions. The hydroxyl can react with a variety of functional groups.

Uses

DBCO-C-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-C-PEG1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-C-PEG1 Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-C-PEG1 Suppliers

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
3935
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55
Alfa Chemistry
Tel
+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Henan Lien Chemical Products Co., Ltd.
Tel
0371-63357898 15378766539
Email
535046669@qq.com
Country
China
ProdList
4642
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
9947
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9681
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Hangzhou Medicine Link Biotechnology Co., LTD
Tel
15088318933 19357585311
Email
wxq6505168@163.com
Country
China
ProdList
43
Advantage
58
Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564 13854185395;
Email
info@easycdmo.com
Country
China
ProdList
10024
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29496
Advantage
58