DBCO-maleimide

Product Name: DBCO-maleimide
CAS No.: 1395786-30-7
Chemical Name: DBCO-maleimide
Synonyms: Dibenzocyclooctyne-maleimide;DBCO-MAL;DBCO-maleimide;DBCO-Maleimide,Dibenzocyclooctyne-maleimide;DBCO-maleimide (This product is unavailable in the U.S.);DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5);Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.);1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-;N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide;N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
CBNumber: CB92985649
Molecular Formula: C25H21N3O4
Formula Weight: 427.45
MOL File: 1395786-30-7.mol

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DBCO-maleimide Property

Melting point:: 162 °C
Boiling point:: 790.5±60.0 °C(Predicted)
Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO, DCM, DMF
form: Solid
pka: 15.03±0.46(Predicted)
color: Off-white to Gray

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Safety

Hazard Codes: N
Risk Statements: 50
Safety Statements: 61

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H400Very toxic to aquatic life
Precautionary statements: P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 1MG
Price: $32.8
Updated: 2023/06/20

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 5MG
Price: $101
Updated: 2023/06/20

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 50MG
Price: $393
Updated: 2023/06/20

TRC

Product number: A939575
Product name: Dbco-Maleimide
Packaging: 1mg
Price: $40
Updated: 2021/12/16

Chem-Impex

Product number: 35063
Product name: DBCOmaleimide,95%(HPLC)
Purity: 95%(HPLC)
Packaging: 5MG
Price: $56
Updated: 2021/12/16

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DBCO-maleimide Chemical Properties,Usage,Production

Description

DBCO-Maleimide is a sulfhydryl reactive reagent containing a maleimide group and a DBCO moiety. Maleimide group specifically and efficiently reacts with thiols to form thioether bonds. The low mass weight will add minimal spacer to modified molecules and will enable simple and efficient incorporation of DBCO moiety into cysteine-containing peptides or other thiol-containing biomolecules. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

Protein-peptide conjugates
Antibody-enzyme or antibody-drug conjugates
Protein or peptide-oligonucleotide conjugates
Surface modification

Uses

Dbco-Maleimide is used in preparation of radioactive metal indicator-chelating peptide derivative-conjugated antibodies for medical imaging.

DBCO-maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-maleimide Suppliers

China 67 Europe 1 India 1 Japan 1 United States 7 Global 77

TCI (Shanghai) Development Co., Ltd.

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Adamas Reagent, Ltd.

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Shandong Xiya Chemical Co., Ltd

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TOKYO CHEMICAL INDUSTRY CO., LTD.

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TCI Europe

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Sigma-Aldrich

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Shanghai Send Pharmaceutical Technology Co., Ltd.

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Jinan elephant international trading co., LTD

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View Lastest Price from DBCO-maleimide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-Maleimide 1395786-30-7
Price: US $0.00/mg
Min. Order: 25mg
Purity: >98.00%
Supply Ability: 250
Release date: 2024-03-20

1395786-30-7, DBCO-maleimideRelated Search:

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DBCO-maleimide

Dibenzocyclooctyne-maleimide

Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.)

1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-

DBCO-Maleimide,Dibenzocyclooctyne-maleimide

DBCO-maleimide (This product is unavailable in the U.S.)

DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5)

N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide

DBCO-MAL

N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide

1395786-30-7

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