DBCO-maleimide

Product Name: DBCO-maleimide
CAS No.: 1395786-30-7
Chemical Name: DBCO-maleimide
Synonyms: Dibenzocyclooctyne-maleimide;DBCO-MAL;DBCO-maleimide;DBCO-Maleimide,Dibenzocyclooctyne-maleimide;DBCO-maleimide (This product is unavailable in the U.S.);DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5);Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.);1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-;N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide;N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
CBNumber: CB92985649
Molecular Formula: C25H21N3O4
Formula Weight: 427.45
MOL File: 1395786-30-7.mol

More

Less

DBCO-maleimide Property

Melting point:: 162 °C
Boiling point:: 790.5±60.0 °C(Predicted)
Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO, DCM, DMF
form: Solid
pka: 15.03±0.46(Predicted)
color: Off-white to Gray

More

Less

Safety

Hazard Codes: N
Risk Statements: 50
Safety Statements: 61

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H400Very toxic to aquatic life
Precautionary statements: P273Avoid release to the environment.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 1MG
Price: $32.8
Updated: 2023/06/20

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 5MG
Price: $101
Updated: 2023/06/20

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 50MG
Price: $393
Updated: 2023/06/20

TRC

Product number: A939575
Product name: Dbco-Maleimide
Packaging: 1mg
Price: $40
Updated: 2021/12/16

Chem-Impex

Product number: 35063
Product name: DBCOmaleimide,95%(HPLC)
Purity: 95%(HPLC)
Packaging: 5MG
Price: $56
Updated: 2021/12/16

More

Less

DBCO-maleimide Chemical Properties,Usage,Production

Description

DBCO-Maleimide is a sulfhydryl reactive reagent containing a maleimide group and a DBCO moiety. Maleimide group specifically and efficiently reacts with thiols to form thioether bonds. The low mass weight will add minimal spacer to modified molecules and will enable simple and efficient incorporation of DBCO moiety into cysteine-containing peptides or other thiol-containing biomolecules. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

Protein-peptide conjugates
Antibody-enzyme or antibody-drug conjugates
Protein or peptide-oligonucleotide conjugates
Surface modification

Uses

Dbco-Maleimide is used in preparation of radioactive metal indicator-chelating peptide derivative-conjugated antibodies for medical imaging.

DBCO-maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DBCO-maleimide Suppliers

China 66 Europe 1 India 1 Japan 1 United States 7 Global 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
Email: cb6@aikonchem.com
Country: China
ProdList: 16684
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q3382968513
Fax: QQ3382968513
Email: danping@shsendpharm.com
Country: China
ProdList: 3128
Advantage: 55

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

More

Less

View Lastest Price from DBCO-maleimide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-Maleimide 1395786-30-7
Price: US $0.00/mg
Min. Order: 25mg
Purity: >98.00%
Supply Ability: 250
Release date: 2024-03-20

1395786-30-7, DBCO-maleimideRelated Search:

Oleic-DBCO DBCO-C-PEG1 DBCO-C6-acid DBCO-(CH2)2-NH2-CO-(CH2)2COOH DBCO-NHS Ester DBCO-(CH2)2-NH2-CO-(CH2)3COOH DBCO-(CH2)3-Acid DBCO-PEG11-amine 3-Maleimidopropionic acid DBCO-PEG4-Acid DBCO-PEG3-amine DBCO-amine 2-(4-Ethyl-1-piperazinyl)-4-[4-(4-ethyl-1-piperazinyl)phenyl]-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine DBCO-PEG4-amine DBCO-PEG4-maleimide BDP FL DBCO DBCO-PEG4-TAMRA DBCO-PEG5-CH2CH2COOH

DBCO-maleimide

Dibenzocyclooctyne-maleimide

Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.)

1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-

DBCO-Maleimide,Dibenzocyclooctyne-maleimide

DBCO-maleimide (This product is unavailable in the U.S.)

DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5)

N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide

DBCO-MAL

N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide

1395786-30-7

ADC LINKER