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DBCO-PEG4-Acid

Product Name
DBCO-PEG4-Acid
CAS No.
1537170-85-6
Chemical Name
DBCO-PEG4-Acid
Synonyms
DBCO-PEG4-C2-acid;DBCO-PEG4-COOH;DBCO-PEG4-Acid;ADIBO-PEG4-acid;Aurumpharma u63872;DBCO-CONH-PEG4-acid;DBCO-CONH-PEG4-CH2CH2COOH;ADIBO-PEG4-acid 90% (HPLC);Dibenzocyclooctyne-PEG4-acid;DBCO-PEG4-acid,DBCO-PEG4-COOH
CBNumber
CB92925267
Molecular Formula
C30H36N2O8
Formula Weight
552.62
MOL File
1537170-85-6.mol
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DBCO-PEG4-Acid Property

Boiling point:
839.7±65.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO, DCM, DMF
form 
Solid or Viscous Liquid
pka
4.28±0.10(Predicted)
color 
Yellow to Orange
InChIKey
LKSAMQQFMTVPKD-UHFFFAOYSA-N
SMILES
C(O)(=O)CCOCCOCCOCCOCCNC(=O)CCC(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
759902
Product name
Dibenzocyclooctyne-PEG4-acid
Purity
for Copper-free Click Chemistry
Packaging
5MG
Price
$71.7
Updated
2025/07/31
Sigma-Aldrich
Product number
797685
Product name
ADIBO-PEG4-acid
Purity
90% (HPLC)
Packaging
100mg
Price
$983
Updated
2025/07/31
Sigma-Aldrich
Product number
759902
Product name
Dibenzocyclooctyne-PEG4-acid
Purity
for Copper-free Click Chemistry
Packaging
50MG
Price
$451.89
Updated
2025/07/31
BroadPharm
Product number
BP-23809
Product name
DBCO-PEG4-acid
Purity
98%
Packaging
25mg
Price
$170
Updated
2021/12/16
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DBCO-PEG4-Acid Chemical Properties,Usage,Production

Description

DBCO-PEG4-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.

reaction suitability

reaction type: click chemistry
reagent type: linker

IC 50

PEGs

DBCO-PEG4-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG4-Acid Suppliers

Suzhou Derivative Biotechnology Co., Ltd.
Tel
13915541704
Email
2436368162@qq.com
Country
China
ProdList
554
Advantage
58
Zhejiang Rui 'ao Biological Technology Co.,LTD.
Tel
+86-573-82087565 15757883359
Email
yan@ruiaochem.cn
Country
China
ProdList
640
Advantage
58
Biomatrik (Jiaxing) Inc.
Tel
573-573-82623377 18967387295
Fax
+86 (573) 8262-3317
Email
sales@biomatrik.cn
Country
China
ProdList
70
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q2635253576
Fax
QQ3382968513
Email
hailey@shsendpharm.com
Country
China
ProdList
2081
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
8011
Advantage
55
Xiamen Yunfan Biotech Co., Ltd.
Tel
0592-7828678 18050056030
Fax
0592-7828678
Email
357187337@qq.com
Country
China
ProdList
65
Advantage
58
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View Lastest Price from DBCO-PEG4-Acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
DBCO-PEG4-acid 1537170-85-6
Price
US $0.00/mg
Min. Order
50mg
Purity
>98.00%
Supply Ability
250mg
Release date
2024-03-20

1537170-85-6, DBCO-PEG4-AcidRelated Search:


  • DBCO-PEG4-Acid
  • Dibenzocyclooctyne-PEG4-acid
  • ADIBO-PEG4-acid 90% (HPLC)
  • ADIBO-PEG4-acid
  • DBCO-PEG4-acid,DBCO-PEG4-COOH
  • DBCO-CONH-PEG4-acid
  • DBCO-PEG4-C2-acid
  • Aurumpharma u63872
  • 4,7,10,13-Tetraoxa-16-azaeicosanoic acid, 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-
  • DBCO-PEG4-COOH
  • 1-(4-{2-Azatricyclo[10.4.0.0.4,9]hexadeca-1(12),4(9),5,7,13,15-hexaen-10-yn-2-yl}-4-oxobutanamido)-3,6,9,12-tetraoxapentadecan-15-oic acid
  • DBCO-CONH-PEG4-CH2CH2COOH
  • 20-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaeicosanoic acid
  • 1537170-85-6
  • ADC-Linkers