ChemicalBook > CAS DataBase List > DBCO-PEG4-Acid

DBCO-PEG4-Acid

Product Name
DBCO-PEG4-Acid
CAS No.
1537170-85-6
Chemical Name
DBCO-PEG4-Acid
Synonyms
DBCO-PEG4-C2-acid;DBCO-PEG4-COOH;DBCO-PEG4-Acid;ADIBO-PEG4-acid;Aurumpharma u63872;DBCO-CONH-PEG4-acid;DBCO-CONH-PEG4-CH2CH2COOH;ADIBO-PEG4-acid 90% (HPLC);Dibenzocyclooctyne-PEG4-acid;DBCO-PEG4-acid,DBCO-PEG4-COOH
CBNumber
CB92925267
Molecular Formula
C30H36N2O8
Formula Weight
552.62
MOL File
1537170-85-6.mol
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DBCO-PEG4-Acid Property

Boiling point:
839.7±65.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO, DCM, DMF
form 
Solid or Viscous Liquid
pka
4.28±0.10(Predicted)
color 
Yellow to Orange
InChIKey
LKSAMQQFMTVPKD-UHFFFAOYSA-N
SMILES
C(O)(=O)CCOCCOCCOCCOCCNC(=O)CCC(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
759902
Product name
Dibenzocyclooctyne-PEG4-acid
Purity
for Copper-free Click Chemistry
Packaging
5MG
Price
$71.7
Updated
2025/07/31
Sigma-Aldrich
Product number
797685
Product name
ADIBO-PEG4-acid
Purity
90% (HPLC)
Packaging
100mg
Price
$983
Updated
2025/07/31
Sigma-Aldrich
Product number
759902
Product name
Dibenzocyclooctyne-PEG4-acid
Purity
for Copper-free Click Chemistry
Packaging
50MG
Price
$451.89
Updated
2025/07/31
BroadPharm
Product number
BP-23809
Product name
DBCO-PEG4-acid
Purity
98%
Packaging
25mg
Price
$170
Updated
2021/12/16
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DBCO-PEG4-Acid Chemical Properties,Usage,Production

Description

DBCO-PEG4-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.

reaction suitability

reaction type: click chemistry
reagent type: linker

IC 50

PEGs

DBCO-PEG4-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from DBCO-PEG4-Acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
DBCO-PEG4-acid 1537170-85-6
Price
US $0.00/mg
Min. Order
50mg
Purity
>98.00%
Supply Ability
250mg
Release date
2024-03-20

1537170-85-6, DBCO-PEG4-AcidRelated Search:


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  • ADIBO-PEG4-acid 90% (HPLC)
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  • DBCO-CONH-PEG4-CH2CH2COOH
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