DBCO-PEG4-maleimide
- Product Name
- DBCO-PEG4-maleimide
- CAS No.
- 1480516-75-3
- Chemical Name
- DBCO-PEG4-maleimide
- Synonyms
- DBCO-PEG4-MAL;DBCO-dPEG??-MAL;DBCO-PEG4-Maleimid;DBCO-NHCO-PEG4-BMPA;DBCO-PEG4-maleimide;DBCO-NH-PEG4-Maleimide;DBCO-NHCO-PEG4-NH-Maleimide;DBCO-PEG4-Maleimide (CCT-A108P);Dibenzocyclooctyne-PEG4-maleimide;DBCO-PEG4-Maleimide?Chemical Structure
- CBNumber
- CB52925269
- Molecular Formula
- C36H42N4O9
- Formula Weight
- 674.74
- MOL File
- 1480516-75-3.mol
DBCO-PEG4-maleimide Property
- Boiling point:
- 965.2±65.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 15.01±0.46(Predicted)
- form
- Viscous liquid
- color
- Colorless to light yellow
- InChIKey
- VVFZXPZWVJMYPX-UHFFFAOYSA-N
- SMILES
- N1(CCC(NCCOCCOCCOCCOCCC(=O)NCCC(N2CC3=CC=CC=C3C#CC3=CC=CC=C23)=O)=O)C(=O)C=CC1=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
N-Bromosuccinimide Price
- Product number
- 760676
- Product name
- Dibenzocyclooctyne-PEG4-maleimide
- Purity
- for Copper-free Click Chemistry
- Packaging
- 1MG
- Price
- $39.63
- Updated
- 2025/07/31
- Product number
- 760676
- Product name
- Dibenzocyclooctyne-PEG4-maleimide
- Purity
- for Copper-free Click Chemistry
- Packaging
- 5MG
- Price
- $143
- Updated
- 2025/07/31
- Product number
- 760676
- Product name
- Dibenzocyclooctyne-PEG4-maleimide
- Purity
- for Copper-free Click Chemistry
- Packaging
- 50MG
- Price
- $492
- Updated
- 2025/07/31
- Product number
- D195015
- Product name
- DBCO-PEG4-Maleimide
- Packaging
- 1mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 35066
- Product name
- DBCO-PEG4-maleimide,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 5MG
- Price
- $56
- Updated
- 2021/12/16
DBCO-PEG4-maleimide Chemical Properties,Usage,Production
Description
DBCO-PEG4-Maleimide is PEG linker containing a maleimide group and a DBCO moiety. The hydrophilic PEG spacer arm improves solubility in aqueous buffers. Maleimide group specifically and efficiently reacts with thiols to form stable thioether bonds. The low mass weight will add minimal spacer to modified molecules and will enable simple and efficient incorporation of DBCO moiety onto cysteine-containing peptides or other thiol-containing biomolecules. DBCO is commonly used for copper-free Click Chemistry reactions.
Uses
Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG lipophilic spacer helps to reduce aggregation and precipitation problems when labeling biomolecules.
Applications Include:
- Protein-peptide conjugates
- Antibody-enzyme or antibody-drug conjugates
- Protein or peptide-oligonucleotide conjugates
- Surface modification
reaction suitability
reaction type: click chemistry
reagent type: cross-linking reagent
IC 50
Non-cleavable Linker
DBCO-PEG4-maleimide Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG4-maleimide Suppliers
- Tel
- 573-573-82623377 18967387295
- Fax
- +86 (573) 8262-3317
- sales@biomatrik.cn
- Country
- China
- ProdList
- 70
- Advantage
- 61
- Tel
- +86-028-82550498 +86-19102685862
- Fax
- 086-28-82550468
- sales@pu-kang.com
- Country
- China
- ProdList
- 497
- Advantage
- 58
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15873
- Advantage
- 55
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 021-58088081 Q2635253576
- Fax
- QQ3382968513
- hailey@shsendpharm.com
- Country
- China
- ProdList
- 2081
- Advantage
- 55
- Tel
- 526763801 13301653310
- Fax
- +86-21-51619052
- 526763801@qq.com
- Country
- China
- ProdList
- 9274
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- Fax
- -
- 13006575422@163.com
- Country
- China
- ProdList
- 6355
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12306
- Advantage
- 58
- Tel
- 025-58851090 15955137747
- Fax
- (6)02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 15949
- Advantage
- 58
View Lastest Price from DBCO-PEG4-maleimide manufacturers
- Product
- 1H-Pyrrole-1-propanamide, N-[19-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-15,19-dioxo-3,6,9,12-tetraoxa-16-azanonadec-1-yl]-2,5-dihydro-2,5-dioxo- (ACI) 1480516-75-3
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- DBCO-PEG4-Maleimide 1480516-75-3
- Price
- US $0.00/mg
- Min. Order
- 25mg
- Purity
- >99.00%
- Supply Ability
- 100
- Release date
- 2024-03-20