DBCO-PEG4-triethoxysilane
- Product Name
- DBCO-PEG4-triethoxysilane
- CAS No.
- 2353410-02-1
- Chemical Name
- DBCO-PEG4-triethoxysilane
- Synonyms
- DBCO-PEG4-Silane;DBCO-PEG4-triethoxysilane;Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-(20,20-diethoxy-15-oxo-3,6,9,12,21-pentaoxa-16-aza-20-silatricos-1-yl)-γ-oxo-
- CBNumber
- CB04849577
- Molecular Formula
- C39H57N3O10Si
- Formula Weight
- 755.98
- MOL File
- 2353410-02-1.mol
DBCO-PEG4-triethoxysilane Property
- Boiling point:
- 900.0±65.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 15.14±0.46(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-24137
- Product name
- DBCO-PEG4-triethoxysilane
- Purity
- 98%
- Packaging
- 50mg
- Price
- $540
- Updated
- 2021/12/16
DBCO-PEG4-triethoxysilane Chemical Properties,Usage,Production
Description
DBCO-PEG4-triethoxysilane is a PEG linker containing a triethoxysilane moiety and a DBCO group. Triethoxysilane is commonly used for surface modifications. DBCO group can react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. The hydrophilic PEG chain increasse the water solubility of a compound in aqueous media.
Uses
DBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-triethoxysilane is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
DBCO-PEG4-triethoxysilane Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG4-triethoxysilane Suppliers
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View Lastest Price from DBCO-PEG4-triethoxysilane manufacturers
- Product
- DBCO-PEG4-Silane 2353410-02-1
- Price
- US $0.00/mg
- Min. Order
- 25mg
- Purity
- >99.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-20