DBCO-PEG4-triethoxysilane

Product Name: DBCO-PEG4-triethoxysilane
CAS No.: 2353410-02-1
Chemical Name: DBCO-PEG4-triethoxysilane
Synonyms: DBCO-PEG4-Silane;DBCO-PEG4-triethoxysilane;Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-(20,20-diethoxy-15-oxo-3,6,9,12,21-pentaoxa-16-aza-20-silatricos-1-yl)-γ-oxo-
CBNumber: CB04849577
Molecular Formula: C39H57N3O10Si
Formula Weight: 755.98
MOL File: 2353410-02-1.mol

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DBCO-PEG4-triethoxysilane Property

Boiling point:: 900.0±65.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: 15.14±0.46(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24137
Product name: DBCO-PEG4-triethoxysilane
Purity: 98%
Packaging: 50mg
Price: $540
Updated: 2021/12/16

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DBCO-PEG4-triethoxysilane Chemical Properties,Usage,Production

Description

DBCO-PEG4-triethoxysilane is a PEG linker containing a triethoxysilane moiety and a DBCO group. Triethoxysilane is commonly used for surface modifications. DBCO group can react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. The hydrophilic PEG chain increasse the water solubility of a compound in aqueous media.

Uses

DBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-triethoxysilane is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG4-triethoxysilane Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG4-triethoxysilane Suppliers

China 17 United States 3 Global 20

Xi'an Confluore Biological Technology Co., Ltd.

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View Lastest Price from DBCO-PEG4-triethoxysilane manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-PEG4-Silane 2353410-02-1
Price: US $0.00/mg
Min. Order: 25mg
Purity: >99.00%
Supply Ability: 100mg
Release date: 2024-03-20

2353410-02-1, DBCO-PEG4-triethoxysilaneRelated Search:

Propanoic acid, 3-[2-[2-[[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester DBCO-PEG3-OH 4,7,10,13,16,19,22,25-Octaoxa-28-azadotricosanoic acid, 32-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-29,32-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester DBCO-C6-acid DBCO-PEG2-amine DBCO-PEG4-maleimide DBCO-PEG3-Mal 4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester DBCO-Acid DBCO-PEG1 DBCO-PEG4-biotin DBCO-NHCO-PEG2-Biotin Ambient temperature 1H-Pyrrole-1-propanamide, N-[2-[2-[3-[[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethyl]-2,5-dihydro-2,5-dioxo- DBCO-PEG4-Acid N-(6-aminocaproyl)azadibenzocyclooctyne

DBCO-PEG4-triethoxysilane

Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-(20,20-diethoxy-15-oxo-3,6,9,12,21-pentaoxa-16-aza-20-silatricos-1-yl)-γ-oxo-

DBCO-PEG4-Silane

2353410-02-1