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Ambient temperature

Product Name
Ambient temperature
CAS No.
1416711-60-8
Chemical Name
Ambient temperature
Synonyms
DBCO-mPEG, 5 kDa;DBCO-mPEG, 30 kDa;DBCO-mPEG, 20 kDa;DBCO-mPEG, 10 kDa;DBCO-PEG4-Hydroxyl;Ambient temperature;Sulfo DBCO-PEG4-Amine;DBCO-PEG4-OH (CCT-A104);DBCO-PEG4-alcohol, DBCO-PEG4-OH;DBCO-PEG4-Hydroxyl,DBCO-PEG4-OH
CBNumber
CB83339237
Molecular Formula
C29H36N2O6
Formula Weight
508.60594
MOL File
1416711-60-8.mol
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Ambient temperature Property

Boiling point:
785.8±60.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO
pka
14.36±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Chem-Impex
Product number
35075
Product name
DBCO-PEG-OH
Purity
≥ 95% (HPLC)
Packaging
1MG
Price
$50
Updated
2021/12/16
BroadPharm
Product number
BP-22800
Product name
DBCO-PEG4-alcohol
Purity
95%
Packaging
25mg
Price
$95
Updated
2021/12/16
Chem-Impex
Product number
35075
Product name
DBCO-PEG-OH
Purity
≥ 95% (HPLC)
Packaging
5MG
Price
$180
Updated
2021/12/16
Iris Biotech GmbH
Product number
RL-2530
Product name
DBCO-mPEG(5kDa)
Packaging
25mg
Price
$229.5
Updated
2021/12/16
Iris Biotech GmbH
Product number
RL-2550
Product name
DBCO-mPEG(20kDa)
Packaging
25mg
Price
$229.5
Updated
2021/12/16
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Ambient temperature Chemical Properties,Usage,Production

Description

DBCO-PEG4-alcohol is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

DBCO-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-alcohol is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Definition

The temperature of the environment in which an experiment is conducted or in which any physical or chemical event occurs.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Ambient temperature Preparation Products And Raw materials

Raw materials

Preparation Products

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Ambient temperature Suppliers

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
3936
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55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
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China
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6355
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58
Shanghai 9i Technology Co., Ltd.
Tel
021-33555271 18201009191
Fax
021-33555271
Email
MWen@9iLab.com
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China
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Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
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58
Alfa Chemistry
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+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
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United States
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32435
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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13892832556
Email
2440688701@qq.com
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China
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1994
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Shaanxi borno biotechnology co., LTD
Tel
+86-13759708231
Email
asherw9@hotmail.com
Country
China
ProdList
2373
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Shanghai Minhan Pharmaceutical Technology Co., Ltd.
Tel
17612188245
Fax
QQ 2816925681
Email
2816925681@qq.com
Country
China
ProdList
2989
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58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988941452
Fax
QQ:3283937693
Email
YN_research@163.com
Country
China
ProdList
3011
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58
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View Lastest Price from Ambient temperature manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
DBCO-PEG4-OH 1416711-60-8
Price
US $0.00/mg
Min. Order
50mg
Purity
>97.00%
Supply Ability
250mg
Release date
2024-03-20