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Ambient temperature

Product Name
Ambient temperature
CAS No.
1416711-60-8
Chemical Name
Ambient temperature
Synonyms
DBCO-mPEG, 5 kDa;DBCO-mPEG, 30 kDa;DBCO-mPEG, 20 kDa;DBCO-mPEG, 10 kDa;DBCO-PEG4-Hydroxyl;Ambient temperature;Sulfo DBCO-PEG4-Amine;DBCO-PEG4-OH (CCT-A104);DBCO-PEG4-alcohol, DBCO-PEG4-OH;DBCO-PEG4-Hydroxyl,DBCO-PEG4-OH
CBNumber
CB83339237
Molecular Formula
C29H36N2O6
Formula Weight
508.60594
MOL File
1416711-60-8.mol
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Ambient temperature Property

Boiling point:
785.8±60.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO
pka
14.36±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Chem-Impex
Product number
35075
Product name
DBCO-PEG-OH
Purity
≥ 95% (HPLC)
Packaging
1MG
Price
$50
Updated
2021/12/16
BroadPharm
Product number
BP-22800
Product name
DBCO-PEG4-alcohol
Purity
95%
Packaging
25mg
Price
$95
Updated
2021/12/16
Chem-Impex
Product number
35075
Product name
DBCO-PEG-OH
Purity
≥ 95% (HPLC)
Packaging
5MG
Price
$180
Updated
2021/12/16
Iris Biotech GmbH
Product number
RL-2530
Product name
DBCO-mPEG(5kDa)
Packaging
25mg
Price
$229.5
Updated
2021/12/16
Iris Biotech GmbH
Product number
RL-2550
Product name
DBCO-mPEG(20kDa)
Packaging
25mg
Price
$229.5
Updated
2021/12/16
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Ambient temperature Chemical Properties,Usage,Production

Description

DBCO-PEG4-alcohol is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

DBCO-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-alcohol is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Definition

The temperature of the environment in which an experiment is conducted or in which any physical or chemical event occurs.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Ambient temperature Preparation Products And Raw materials

Raw materials

Preparation Products

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Ambient temperature Suppliers

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View Lastest Price from Ambient temperature manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
DBCO-PEG4-OH 1416711-60-8
Price
US $0.00/mg
Min. Order
50mg
Purity
>97.00%
Supply Ability
250mg
Release date
2024-03-20