DBCO-PEG1
- Product Name
- DBCO-PEG1
- CAS No.
- 1839049-33-0
- Chemical Name
- DBCO-PEG1
- Synonyms
- DBCO-PEG1;DBCO-C2-OH;DBCO-C2-alcohol;Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-(2-hydroxyethyl)-γ-oxo-
- CBNumber
- CB68054696
- Molecular Formula
- C21H20N2O3
- Formula Weight
- 348.4
- MOL File
- 1839049-33-0.mol
DBCO-PEG1 Property
- Boiling point:
- 716.8±60.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 14.45±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-24380
- Product name
- DBCO-C2-alcohol
- Purity
- 98%
- Packaging
- 50mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-24380
- Product name
- DBCO-C2-alcohol
- Purity
- 98%
- Packaging
- 100mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- BP-24380
- Product name
- DBCO-C2-alcohol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $890
- Updated
- 2021/12/16
DBCO-PEG1 Chemical Properties,Usage,Production
Description
DBCO-C2-alcohol is a linker containing a DBCO moiety and a terminal primary hydroxyl group. DBCO group can react with azides in copper-free Click Chemistry reactions. The hydroxyl can react with a variety of functional groups.
Uses
DBCO-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
DBCO-PEG1 Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG1 Suppliers
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- 0431-80534353 19917294565
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- Country
- China
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- +1-5166625404;
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- 1-516-927-0118
- Info@alfa-chemistry.com
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- United States
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- +1-781-999-5354; +17819995354
- marketing@targetmol.com
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- United States
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- QQ:3283937693
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- China
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- Tel
- 13303867194
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- Country
- China
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View Lastest Price from DBCO-PEG1 manufacturers
- Product
- DBCO-C2-alcohol 1839049-33-0
- Price
- US $0.00/mg
- Min. Order
- 50mg
- Purity
- >99.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-20