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DBCO-PEG1

Product Name
DBCO-PEG1
CAS No.
1839049-33-0
Chemical Name
DBCO-PEG1
Synonyms
DBCO-PEG1;DBCO-C2-OH;DBCO-C2-alcohol;Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-(2-hydroxyethyl)-γ-oxo-
CBNumber
CB68054696
Molecular Formula
C21H20N2O3
Formula Weight
348.4
MOL File
1839049-33-0.mol
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DBCO-PEG1 Property

Boiling point:
716.8±60.0 °C(Predicted)
Density 
1.30±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO, DCM, DMF
pka
14.45±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-24380
Product name
DBCO-C2-alcohol
Purity
98%
Packaging
50mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-24380
Product name
DBCO-C2-alcohol
Purity
98%
Packaging
100mg
Price
$460
Updated
2021/12/16
BroadPharm
Product number
BP-24380
Product name
DBCO-C2-alcohol
Purity
98%
Packaging
250mg
Price
$890
Updated
2021/12/16
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DBCO-PEG1 Chemical Properties,Usage,Production

Description

DBCO-C2-alcohol is a linker containing a DBCO moiety and a terminal primary hydroxyl group. DBCO group can react with azides in copper-free Click Chemistry reactions. The hydroxyl can react with a variety of functional groups.

Uses

DBCO-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG1 Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG1 Suppliers

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
3935
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Alfa Chemistry
Tel
+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Henan Lien Chemical Products Co., Ltd.
Tel
0371-63357898 15378766539
Email
535046669@qq.com
Country
China
ProdList
4641
Advantage
58
Shanghai Minhan Pharmaceutical Technology Co., Ltd.
Tel
17612188245
Fax
QQ 2816925681
Email
2816925681@qq.com
Country
China
ProdList
2989
Advantage
58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988941452
Fax
QQ:3283937693
Email
YN_research@163.com
Country
China
ProdList
3011
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
9947
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9681
Advantage
58
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View Lastest Price from DBCO-PEG1 manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
DBCO-C2-alcohol 1839049-33-0
Price
US $0.00/mg
Min. Order
50mg
Purity
>99.00%
Supply Ability
250mg
Release date
2024-03-20